Botulinum toxin type B (Myobloc) ( DrugBank: Botulinum toxin type B )

2 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
2	筋萎縮性側索硬化症	1
6	パーキンソン病	1

2. 筋萎縮性側索硬化症

臨床試験数 : 645 / 薬物数 : 589 - (DrugBank : 163) / 標的遺伝子数 : 150 - 標的パスウェイ数 : 225

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00125203 (ClinicalTrials.gov)	July 2003	27/7/2005	Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS)	A Randomized, Double-Blind, Placebo-Controlled Study of Safety and Efficacy of Botulinum Toxin Type B (Myobloc) in Sialorrhea in Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis;Sialorrhea	Drug: Botulinum toxin type B (Myobloc);Procedure: Injection of salivary glands	The University of Texas Health Science Center at San Antonio	ALS Association;University of Kansas;Carolinas MDA Neuromuscular/ALS Center-Carolinas Medical System	Completed	21 Years	85 Years	Both	20	Phase 2/Phase 3	United States

6. パーキンソン病

臨床試験数 : 2,307 / 薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00515437 (ClinicalTrials.gov)	July 2007	10/8/2007	A Multi-Center Study of MYOBLOC for the Treatment of Sialorrhea in Parkinson's Disease Patients	A Multi-Center, Randomized, Double-blind, Placebo-Controlled,Sequential Dose Escalation, Safety, Tolerability, and Preliminary Efficacy Study of MYOBLOC for the Treatment of Sialorrhea in Parkinson's Disease Patients	Drooling	Biological: Botulinum Toxin Type B (Myobloc);Biological: Matched placebo to Myobloc	Solstice Neurosciences	NULL	Completed	18 Years	85 Years	All	54	Phase 2	United States