Talampanel ( DrugBank: Talampanel )


2 diseases
告示番号疾患名(ページ内リンク)臨床試験数
2筋萎縮性側索硬化症9
6パーキンソン病2

2. 筋萎縮性側索硬化症


臨床試験数 : 645 薬物数 : 589 - (DrugBank : 163) / 標的遺伝子数 : 150 - 標的パスウェイ数 : 225
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00982150
(ClinicalTrials.gov)
September 200922/9/2009Extension Study of Talampanel for Amyotrophic Lateral Sclerosis (ALS)A Multinational, Multicenter, Open Label Phase to Assess Tolerability and Safety of Talampanel 50mg Tid in Subjects With Amyotrophic Lateral Sclerosis (ALS)Amyotrophic Lateral SclerosisDrug: TalampanelTeva Pharmaceutical IndustriesNULLTerminated18 Years80 YearsBoth446Phase 2United States;Belgium;Canada;France;Germany;Hungary;Israel;Italy;Netherlands;Spain
2EUCTR2008-002062-62-NL
(EUCTR)
14/10/200802/06/2008A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS)A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) Amyotrophic lateral sclerosis (ALS).
MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Teva Pharmaceutical Industries, LtdNULLNot RecruitingFemale: yes
Male: yes
540Hungary;Germany;Netherlands;Belgium;France;Spain;Italy
3EUCTR2008-002062-62-FR
(EUCTR)
22/09/200819/06/2008A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS)A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) Amyotrophic lateral sclerosis (ALS).
MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Teva Pharmaceutical Industries, LtdNULLNot RecruitingFemale: yes
Male: yes
540Phase 2France;Hungary;Belgium;Spain;Germany;Netherlands;Italy
4EUCTR2008-002062-62-HU
(EUCTR)
17/09/200817/12/2008A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS).A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). Amyotrophic lateral sclerosis (ALS).
MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Teva Pharmaceutical Industries, LtdNULLNot RecruitingFemale: yes
Male: yes
540Hungary;Germany;Netherlands;Belgium;France;Spain;Italy
5EUCTR2008-002062-62-DE
(EUCTR)
08/09/200819/01/2009A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). - ALSTARA Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). - ALSTAR Amyotrophic lateral sclerosis (ALS).
MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Teva Pharmaceutical Industries, LtdNULLNot RecruitingFemale: yes
Male: yes
540Hungary;Germany;Netherlands;Belgium;France;Spain;Italy
6NCT00696332
(ClinicalTrials.gov)
September 200810/6/2008Talampanel for Amyotrophic Lateral Sclerosis (ALS)A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of Talampanel in Subjects With Amyotrophic Lateral Sclerosis (ALS)ALSDrug: Talampanel;Other: placeboTeva Pharmaceutical IndustriesNULLCompleted18 Years80 YearsBoth559Phase 2United States;Belgium;Canada;France;Germany;Hungary;Israel;Italy;Netherlands;Spain
7EUCTR2008-002062-62-ES
(EUCTR)
13/08/200826/06/2008Estudio multinacional, multicéntrico, randomizado, doble ciego, controlado con placebo y de grupos paralelos para evaluar la eficacia, tolerabilidad y seguridad de Talampanel en pacientes con Esclerosis Lateral Amiotrófica (ELA)A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS)Estudio multinacional, multicéntrico, randomizado, doble ciego, controlado con placebo y de grupos paralelos para evaluar la eficacia, tolerabilidad y seguridad de Talampanel en pacientes con Esclerosis Lateral Amiotrófica (ELA)A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) Esclerosis Lateral Amiotrófica (ELA).Amyotrophic lateral sclerosis (ALS).
MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Teva Pharmaceutical Industries, LtdNULLNot RecruitingFemale: yes
Male: yes
540Phase 2France;Hungary;Belgium;Spain;Germany;Netherlands;Italy
8EUCTR2008-002062-62-BE
(EUCTR)
31/07/200811/07/2008A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS).A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS).ALS-TAL-201-OL is added as an open label extension of the ALS-TAL-201 trial: A Multinational, Multicenter, Open label phase to Assess Tolerability and Safety of Talampanel 50mg tid in Subjects with Amyotrophic Lateral Sclerosis (ALS). Amyotrophic lateral sclerosis (ALS).
MedDRA version: 9.1;Level: PT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Product Name: talampanel
Product Code: TV-7110
INN or Proposed INN: Not available yet
Other descriptive name: talampanel
Teva Pharmaceutical Industries, LtdNULLNot RecruitingFemale: yes
Male: yes
540Hungary;Germany;Netherlands;Belgium;France;Spain;Italy
9EUCTR2008-002062-62-IT
(EUCTR)
16/06/200827/06/2008A Multinational, Multicenter, Randomized, Double-Blind, Placebo- Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) - ALSTARA Multinational, Multicenter, Randomized, Double-Blind, Placebo- Controlled, Parallel-Group Study to Assess the Efficacy, Tolerability and Safety of talampanel in Subjects with Amyotrophic Lateral Sclerosis (ALS) - ALSTAR Amyotrophic Lateral Sclerosis
MedDRA version: 9.1;Level: LLT;Classification code 10052653;Term: Amyotrophic lateral sclerosis gene carrier
Product Name: tallampanel
Product Code: TV-7110
Product Name: talampanel
Teva Pharmaceutical Industries,LtdNULLNot RecruitingFemale: yes
Male: yes
540Hungary;Germany;Netherlands;Belgium;France;Spain;Italy

6. パーキンソン病


臨床試験数 : 2,307 薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00036296
(ClinicalTrials.gov)
December 20068/5/2002Effects of Talampanel on Patients With Advanced Parkinson's DiseaseEffects of Talampanel on Patients With Advanced Parkinson's Disease Who Have Been on Sinemet for More Than 5 Years and Have Dyskinesia (Abnormal Involuntary Movements)Dyskinesias;Parkinson Disease;Movement DisordersDrug: talampanelTeva Pharmaceutical IndustriesNULLCompleted40 Years85 YearsBoth22Phase 1/Phase 2United States;Canada
2NCT00108667
(ClinicalTrials.gov)
April 200515/4/2005Talampanel to Treat Parkinson's DiseaseAMPA Receptor Antagonist Treatment of Parkinson's DiseaseParkinson DiseaseDrug: IV Levodopa;Drug: TalampanelNational Institute of Neurological Disorders and Stroke (NINDS)NULLCompletedN/AN/ABoth40Phase 2United States