GLP-1 ( DrugBank: - )

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1 disease

告示番号	疾患名（ページ内リンク）	臨床試験数
299	嚢胞性線維症	3

299. 嚢胞性線維症

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臨床試験数 : 1,695 /  薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04731272 (ClinicalTrials.gov)	April 20, 2021	26/1/2021	GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance	Effect of GLP-1 Agonist Therapy on Insulin Secretion in Adults With Pancreatic Insufficient Cystic Fibrosis and Abnormal Glucose Tolerance: a Randomized, Open-label, Cross-over Trial	Cystic Fibrosis;Pancreatic Insufficiency;Abnormal Glucose Tolerance;Diabetes	Drug: Dulaglutide 0.75Mg/0.5Ml Inj Pen	University of Pennsylvania	Children's Hospital of Philadelphia	Recruiting	18 Years	N/A	All	30	Phase 2	United States
2	NCT01975259 (ClinicalTrials.gov)	December 2013	11/9/2013	Investigating the Incretin Effect in Cystic Fibrosis	Investigating the Incretin Effect in Cystic Fibrosis	Cystic Fibrosis	Drug: Oral Glucose Tolerance test (75g 2-hour);Drug: Modified Oral Glucose Tolerance Test (50g 4-hours);Drug: Matched isoglycemic clamp;Drug: Hyperglycemic clamp with concurrent GLP-1 infusion;Drug: Hyperglycemic Clamp with concurrent GIP infusion;Drug: Hyperglycemic clamp with placebo infusion;Other: Liquid Meal Test (Carbohydrate-rich);Other: Liquid Meal Test (Fat-rich);Other: Liquid Meal Test (Mixed);Device: Continuous Glucose Monitoring	Liverpool Heart and Chest Hospital NHS Foundation Trust	NULL	Completed	17 Years	50 Years	Both	50	N/A	United Kingdom
3	NCT01851694 (ClinicalTrials.gov)	May 2013	8/5/2013	Beta-cell Response to Incretin Hormones in Cystic Fibrosis	Determination of Beta-cell Responsiveness to the Incretin Hormones GLP-1 and GIP in Cystic Fibrosis	Cystic Fibrosis;Pancreatic Insufficiency	Drug: GLP-1;Drug: GIP	University of Pennsylvania	Children's Hospital of Philadelphia	Recruiting	18 Years	N/A	All	45	N/A	United States