GSK1070806 ( DrugBank: - )


2 diseases
告示番号疾患名(ページ内リンク)臨床試験数
56ベーチェット病1
96クローン病2

56. ベーチェット病


臨床試験数 : 81 薬物数 : 107 - (DrugBank : 30) / 標的遺伝子数 : 36 - 標的パスウェイ数 : 116
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03522662
(ClinicalTrials.gov)
August 1, 20181/5/2018Anti IL-18 (GSK1070806) in Behcet's DiseaseAn Experimental Medicine Study to Characterise the Importance of IL-18 Production and to Evaluate the Therapeutic Potential of IL-18 Blockade With GSK1070806 in Subjects With Behcet's DiseaseBehcet's DiseaseDrug: GSK1070806Cambridge University Hospitals NHS Foundation TrustNULLUnknown status18 YearsN/AAll12Phase 2United Kingdom

96. クローン病


臨床試験数 : 2,442 薬物数 : 1,278 - (DrugBank : 248) / 標的遺伝子数 : 142 - 標的パスウェイ数 : 209
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03681067
(ClinicalTrials.gov)
February 20, 201920/8/2018A Clinical Trial of Antibody GSK1070806 in the Treatment of Patients With Moderate to Severe Crohn's DiseaseA Phase Ib/IIb, Randomised, Double Blind, Placebo-Controlled Trial to Investigate the Safety, Tolerability and Clinical Activity of Humanised Antibody GSK1070806 in the Treatment of Patients With Moderate-to-Severe Crohn's DiseaseCrohn DiseaseDrug: GSK1070806;Drug: Placebo- sodium chlorideUniversity of BirminghamGlaxoSmithKline;University Hospital BirminghamCompleted16 YearsN/AAll5Phase 1/Phase 2United Kingdom
2EUCTR2018-002001-65-GB
(EUCTR)
13/12/201801/10/2018A clinical trial of antibody GSK1070806 in the treatment of patients with moderate to severe Crohn’s DiseaseA Phase Ib/IIb, Randomised, Double Blind, Placebo-Controlled Trial to Investigate the Safety, Tolerability and Clinical Activity of Humanised Antibody GSK1070806 in the Treatment of Patients with Moderate-to-Severe Crohn’s Disease - CDAID GSK1070806 Crohn's disease
MedDRA version: 20.0;Level: LLT;Classification code 10013099;Term: Disease Crohns;System Organ Class: 100000004856 ;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: GSK1070806
INN or Proposed INN: GSK1070806
Other descriptive name: fully humanised, recombinant monoclonal antibody (IgG1)
University of BirminghamNULLAuthorised-recruitment may be ongoing or finished Female: yes
Male: yes
36 Human pharmacology (Phase 1): yes Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): noUnited Kingdom