Sitagliptin ( DrugBank: Sitagliptin )


4 diseases
告示番号疾患名(ページ内リンク)臨床試験数
6パーキンソン病1
75クッシング病1
233ウォルフラム症候群1
299嚢胞性線維症4

6. パーキンソン病


臨床試験数 : 2,307 薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1ChiCTR2000029465
2020-04-062020-02-02Comparison of effects of sitagliptin and metformin on motor function and cognitive function in patients with Parkinson's disease complicated with type 2 diabetesComparison of effects of sitagliptin and metformin on motor function and cognitive function in patients with Parkinson's disease complicated with type 2 diabetes Type 2 DiabetesSitagliptin group:Sitagliptin 100mg/d for 52 weeks;metformin group:metformin 1000-1500mg/d for 52 weeks;Peking Union Medical College HospitalNULLPending1875BothSitagliptin group:20;metformin group:20;Phase 4China

75. クッシング病


臨床試験数 : 205 薬物数 : 176 - (DrugBank : 45) / 標的遺伝子数 : 61 - 標的パスウェイ数 : 127
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT02060383
(ClinicalTrials.gov)
May 23, 201410/2/2014Study of Management of Pasireotide-induced Hyperglycemia in Adult Patients With Cushing's Disease or AcromegalyA Multi-center, Randomized, Open-label, Phase IV Study to Investigate the Management of Pasireotide-induced Hyperglycemia With Incretin Based Therapy or Insulin in Adult Patients With Cushing's Disease or AcromegalyCushing's Disease;AcromegalyDrug: Pasireotide s.c.;Drug: Sitagliptin;Drug: Liraglutide;Drug: Insulin;Drug: Pasireotide LAR;Drug: MetforminNovartis PharmaceuticalsNULLCompleted18 YearsN/AAll249Phase 4United States;Belgium;Brazil;China;Denmark;Germany;India;Peru;Poland;Russian Federation;Thailand;Turkey

233. ウォルフラム症候群


臨床試験数 : 11 薬物数 : 17 - (DrugBank : 8) / 標的遺伝子数 : 12 - 標的パスウェイ数 : 41
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT02882477
(ClinicalTrials.gov)
December 201617/7/2016Treatment of Wolfram Syndrome Type 2 With the Chelator Deferiprone and Incretin Based TherapyTreatment of Wolfram Syndrome Type 2 With the Chelator Deferiprone, and Incretin Based TherapyDiabetes Mellitus;Iron Metabolism Disorders;Gastroduodenal Ulcer;Optic Atrophy;Sensorineural Hearing Loss;Platelet DysfunctionDrug: Deferiprone;Drug: Acetylcysteine;Drug: Sitagliptin and MetforminHadassah Medical OrganizationNULLNot yet recruiting3 YearsN/ABoth20Phase 2/Phase 3Israel

299. 嚢胞性線維症


臨床試験数 : 1,695 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT01879228
(ClinicalTrials.gov)
June 201312/6/2013Effect of Chronic Incretin-based Therapy in Cystic FibrosisA Randomized, Double-blind, Placebo Controlled Study of the Effectiveness of Chronic Incretin-based Therapy on Insulin Secretion in Cystic FibrosisCystic Fibrosis;Pancreatic InsufficiencyDrug: SitagliptinUniversity of PennsylvaniaChildren's Hospital of PhiladelphiaCompleted18 YearsN/AAll26N/AUnited States
2NCT01721382
(ClinicalTrials.gov)
November 201226/10/2012Treatment of Dysglycemia Using Sitagliptin in Adolescents With Cystic FibrosisTreatment of Dysglycemia Using Sitagliptin in Adolescents With Cystic Fibrosis.Cystic FibrosisDrug: SitagliptinNemours Children's ClinicNULLCompleted13 Years20 YearsBoth6Phase 1United States
3NCT01257464
(ClinicalTrials.gov)
September 20102/12/2010Sitagliptin in Cystic Fibrosis-Related DiabetesThe Effects of the DPPIV Inhibitor Sitagliptin in Cystic Fibrosis-related DiabetesCystic FibrosisDrug: Sitagliptin;Drug: PlaceboUniversity of British ColumbiaNULLTerminated19 YearsN/ABoth3Phase 2Canada
4NCT00967798
(ClinicalTrials.gov)
May 201027/8/2009Prevention of Cystic Fibrosis DiabetesA Randomized, Double-blind, Placebo-controlled Study to Determine Whether Chronic Treatment of Cystic Fibrosis Subjects With Impaired Glucose Tolerance Using Sitagliptin (Januvia) Prevents the Development of DiabetesCystic Fibrosis;PrediabetesDrug: SitagliptinEmory UniversityNULLTerminated13 YearsN/AAll33Phase 3United States;Canada