Rilzabrutinib ( DrugBank: - )
2 diseases
| 告示番号 | 疾患名（ページ内リンク） | 臨床試験数 |
|---|---|---|
| 61 | 自己免疫性溶血性貧血 | 4 |
| 300 | IgG4関連疾患 | 1 |
61. 自己免疫性溶血性貧血
臨床試験数 : 146 / 薬物数 : 131 - (DrugBank : 59) / 標的遺伝子数 : 28 - 標的パスウェイ数 : 158
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05002777 (ClinicalTrials.gov) | December 7, 2021 | 5/8/2021 | Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic Anemia (wAIHA) | A Multicenter, Open-label, Phase IIb Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic Anemia | Warm Autoimmune Hemolytic Anemia (wAIHA) | Drug: rilzabrutinib | Sanofi | NULL | Recruiting | 18 Years | N/A | All | 20 | Phase 2 | United States;China;Denmark;Italy;Spain;United Kingdom |
| 2 | EUCTR2021-001671-16-DK (EUCTR) | 15/11/2021 | 16/07/2021 | Efficacy, safety and pharmacokinetics of rilzabrutinib in patients with warm autoimmune hemolytic anemia | A multicenter, open-label, Phase IIb study to evaluate the efficacy, safety and pharmacokinetics of rilzabrutinib in patients with warm autoimmune hemolytic anemia | Warm autoimmune hemolytic anemia MedDRA version: 20.0;Level: PT;Classification code 10073785;Term: Autoimmune haemolytic anaemia;System Organ Class: 10005329 - Blood and lymphatic system disorders;Therapeutic area: Diseases [C] - Immune System Diseases [C20] | Product Name: Rilzabrutinib Product Code: SAR444671 INN or Proposed INN: Rilzabrutinib Other descriptive name: PRN1008 | Sanofi aventis recherche et developpement | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 25 | Phase 2 | France;United States;Hungary;Spain;Austria;Denmark;Germany;United Kingdom;Italy;China | ||
| 3 | EUCTR2021-001671-16-ES (EUCTR) | 08/10/2021 | 23/06/2021 | Efficacy, safety and pharmacokinetics of rilzabrutinib in patients with warm autoimmune hemolytic anemia | A multicenter, open-label, Phase IIb study to evaluate the efficacy, safety and pharmacokinetics of rilzabrutinib in patients with warm autoimmune hemolytic anemia | Warm autoimmune hemolytic anemia MedDRA version: 20.0;Level: PT;Classification code 10073785;Term: Autoimmune haemolytic anaemia;System Organ Class: 10005329 - Blood and lymphatic system disorders;Therapeutic area: Diseases [C] - Immune System Diseases [C20] | Product Name: Rilzabrutinib Product Code: SAR444671 INN or Proposed INN: Rilzabrutinib Other descriptive name: PRN1008 | Sanofi aventis recherche et developpement | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 25 | Phase 2 | United States;Spain;Denmark;United Kingdom;Italy;China | ||
| 4 | EUCTR2021-001671-16-IT (EUCTR) | 24/09/2021 | 12/10/2021 | Efficacy, safety and pharmacokinetics of rilzabrutinib in patients with warmautoimmune hemolytic anemia | A multicenter, open-label, Phase IIb study to evaluate the efficacy, safety and pharmacokinetics of rilzabrutinib in patients with warm autoimmune hemolytic anemia - . | Warm autoimmune hemolytic anemia MedDRA version: 20.0;Level: PT;Classification code 10073785;Term: Autoimmune haemolytic anaemia;System Organ Class: 10005329 - Blood and lymphatic system disorders;Therapeutic area: Diseases [C] - Immune System Diseases [C20] | Product Name: Rilzabrutinib Product Code: [SAR444671] INN or Proposed INN: Rilzabrutinib Other descriptive name: PRN1008 | SANOFI-AVENTIS RECHERCHE E DEVELOPPEMENT | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 25 | Phase 2 | United States;Spain;Denmark;United Kingdom;China;Italy |
300. IgG4関連疾患
臨床試験数 : 40 / 薬物数 : 47 - (DrugBank : 21) / 標的遺伝子数 : 18 - 標的パスウェイ数 : 141
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04520451 (ClinicalTrials.gov) | August 22, 2020 | 11/8/2020 | Open Label Two-Arm Study to Evaluate Rilzabrutinib in IgG4-Related Disease Patients | An Open Label, Two-Arm Study to Evaluate the Effect of Rilzabrutinib (PRN1008/SAR444671) on Safety and Disease Activity in Patients With IgG4-Related Disease | Immunoglobulin G4 Related Disease | Drug: rilzabrutinib;Drug: Glucocorticoids | Principia Biopharma, a Sanofi Company | Massachusetts General Hospital | Recruiting | 18 Years | N/A | All | 25 | Phase 2 | United States;Canada |