Bryostatin 1 ( DrugBank: Bryostatin 1 )


1 disease
告示番号疾患名(ページ内リンク)臨床試験数
62発作性夜間ヘモグロビン尿症1

62. 発作性夜間ヘモグロビン尿症


臨床試験数 : 292 薬物数 : 151 - (DrugBank : 49) / 標的遺伝子数 : 22 - 標的パスウェイ数 : 108
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agemin
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agemax
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PhaseCountries
1NCT00012376
(ClinicalTrials.gov)
March 20013/3/2001Chemotherapy Plus Sargramostim in Treating Patients With Refractory Myeloid CancerDose Finding Study of Bryostatin-1 and GM-CSF in Refractory Myeloid MalignanciesAccelerated Phase Chronic Myelogenous Leukemia;Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;Adult Acute Myeloid Leukemia With Del(5q);Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);Adult Acute Myeloid Leukemia With t(16;16)(p13;Adult Acute Myeloid Leukemia With t(8;21)(q22;Blastic Phase Chronic Myelogenous Leukemia;Chronic Myelomonocytic Leukemia;Chronic Phase Chronic Myelogenous Leukemia;Paroxysmal Nocturnal Hemoglobinuria;Previously Treated Myelodysplastic Syndromes;Recurrent Adult Acute Myeloid Leukemia;Refractory Anemia;Refractory Anemia With Ringed Sideroblasts;Relapsing Chronic Myelogenous Leukemia;Thrombocytopenia;Untreated Adult Acute Myeloid LeukemiaDrug: bryostatin 1;Biological: sargramostim;Other: laboratory biomarker analysis;Other: pharmacological studyNational Cancer Institute (NCI)NULLCompleted18 YearsN/ABoth35Phase 1United States