Tetrahydrocannabinol ( DrugBank: Tetrahydrocannabinol )

4 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
8	ハンチントン病	1
13	多発性硬化症／視神経脊髄炎	28
36	表皮水疱症	1
298	遺伝性膵炎	2

8. ハンチントン病

臨床試験数 : 242 / 薬物数 : 205 - (DrugBank : 62) / 標的遺伝子数 : 85 - 標的パスウェイ数 : 159

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01502046 (ClinicalTrials.gov)	September 2011	29/12/2011	Neuroprotection by Cannabinoids in Huntington's Disease	A Double Blind, Randomized, Cross Over, Placebo Controlled Phase 2 Clinical Trial to Asses Neuroprot ...	Huntington's Disease	Drug: delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD);Drug: Placebo	Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal	GW Pharmaceuticals Ltd.	Completed	18 Years	N/A	Both	25	Phase 2	Spain

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13. 多発性硬化症／視神経脊髄炎

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05269628 (ClinicalTrials.gov)	March 25, 2022	13/2/2022	Mechanisms of Cannabidiol in Persons With MS: the Role of Sleep and Pain Phenotype	Mechanisms of Cannabidiol (CBD) in Persons With Multiple Sclerosis (MS): the Role of Sleep and Pain ...	Multiple Sclerosis;Sleep;Pain	Drug: Cannabidiol (CBD);Drug: Tetrahydrocannabinol (THC);Drug: Placebo CBD;Drug: Placebo THC	Tiffany J. Braley, MD, MS	National Center for Complementary and Integrative Health (NCCIH)	Recruiting	18 Years	65 Years	All	166	Phase 2	United States
2	EUCTR2020-004306-58-LT (EUCTR)	28/01/2022	25/11/2021	A study to asses the effects of Nabiximols on spasticity associated with multiple sclerosis.	A randomized double-blind placebo-controlled study of nabiximols in patients with spasticity in mult ...	Symptomatic treatment of spasticity in patients with MS MedDRA version: 20.1;Level: PT;Classificatio ...	Product Name: Nabiximols - Sativex INN or Proposed INN: TetrahydrocannabinolBotanical Drug Substance ...	GW Pharma Limited	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	575	Phase 3	United States;Hungary;Canada;Spain;Lithuania;Bulgaria;United Kingdom;Italy
3	EUCTR2020-003271-18-ES (EUCTR)	01/07/2021	05/07/2021	A trial to test how efficient Nabiximols is for treatment of spacticity in patients with Multiple Sc ...	A Randomized, Double-blind, Placebo-controlled, 2-way Crossover Trial to Evaluate the Effect of Nabi ...	Symptomatic treatment of spasticity in patients with multiple sclerosis (MS) MedDRA version: 20.0;Le ...	Trade Name: Sativex 2,7mg/2,5 mg Solucion para pulverizacion bucal Product Name: Nabiximols - Sativex ...	GW Pharma Limited	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	190	Phase 3	Czechia;Czech Republic;Poland;Belgium;Spain;Australia;United Kingdom;Sweden
4	EUCTR2020-003271-18-CZ (EUCTR)	07/06/2021	07/04/2021	A trial to test how efficient Nabiximols is for treatment of spacticity in patients with Multiple Sc ...	A Randomized, Double-blind, Placebo-controlled, 2-way Crossover Trial to Evaluate the Effect of Nabi ...	Symptomatic treatment of spasticity in patients with multiple sclerosis (MS) MedDRA version: 20.0;Le ...	Trade Name: Sativex Oromucosal Spray Product Name: Nabiximols - Sativex INN or Proposed INN: Tetrahydr ...	GW Pharma Limited	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	190	Phase 3	United States;Czechia;Czech Republic;Spain;Poland;United Kingdom
5	EUCTR2019-002625-29-CZ (EUCTR)	18/05/2021	10/03/2021	A trial to test how efficient Nabiximols is for treatment of spacticity in patients with Multiple Sc ...	A Randomized, Double-blind, Placebo-controlled, 2-way Crossover Trial to Evaluate the Effect of Nabi ...	Symptomatic treatment of spasticity in patients with multiple sclerosis (MS) MedDRA version: 20.0;Le ...	Trade Name: Sativex Oromucosal Spray Product Name: Nabiximols - Sativex INN or Proposed INN: Tetrahydr ...	GW Pharma Limited	NULL	Not Recruiting			Female: yes Male: yes	104	Phase 3	Czechia;Czech Republic;Poland;United Kingdom
6	EUCTR2019-002623-14-PL (EUCTR)	15/04/2020	21/01/2020	A study to evaluate the efficacy and safety of nabiximols oromucosal spray as add-on therapy in pati ...	A Double-blind, Randomized, Placebo-controlled, Parallel-group Trial of the Efficacy and Safety of N ...	Symptomatic relief of spasticity in Multiple Sclerosis MedDRA version: 20.1;Level: PT;Classification ...	Trade Name: Sativex INN or Proposed INN: TetrahydrocannabinolBotanical Drug Substance (THC BDS) Other ...	GW Pharma Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	446	Phase 3	United States;Czechia;Czech Republic;Poland;Romania;United Kingdom
7	EUCTR2019-002623-14-CZ (EUCTR)	17/03/2020	19/12/2019	A study to evaluate the efficacy and safety of nabiximols oromucosal spray as add-on therapy in pati ...	A Double-blind, Randomized, Placebo-controlled, Parallel-group Trial of the Efficacy and Safety of N ...	Symptomatic relief of spasticity in Multiple Sclerosis MedDRA version: 20.1;Level: PT;Classification ...	Trade Name: Sativex Oromucosal Spray (non-marketed) INN or Proposed INN: TetrahydrocannabinolBotanica ...	GW Pharma Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	446	Phase 3	United States;Czechia;Czech Republic;Poland;Romania;United Kingdom
8	EUCTR2019-002625-29-GB (EUCTR)	16/03/2020	18/06/2020	A trial to test how efficient Nabiximols is for treatment of spacticity in patients with Multiple Sc ...	A Randomized, Double-blind, Placebo-controlled, 2-way Crossover Trial to Evaluate the Effect of Nabi ...	Symptomatic treatment of spasticity in patients with multiple sclerosis (MS) MedDRA version: 20.0;Le ...	Trade Name: Sativex Oromucosal Spray Product Name: Sativex Oromucosal Spray INN or Proposed INN: Tetra ...	GW Pharma Limited	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	52	Phase 3	Poland;United Kingdom
9	EUCTR2019-002623-14-GB (EUCTR)	24/02/2020	18/03/2020	A study to evaluate the efficacy and safety of nabiximols oromucosal spray as add-on therapy in pati ...	A Double-blind, Randomized, Placebo-controlled, Parallel-group Trial of the Efficacy and Safety of N ...	Symptomatic relief of spasticity in Multiple Sclerosis MedDRA version: 20.1;Level: PT;Classification ...	Trade Name: UK: Sativex Oromucosal Spray Product Name: UK: Sativex Oromucosal Spray INN or Proposed IN ...	GW Pharma Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	446	Phase 3	United States;Czech Republic;Poland;Romania;United Kingdom
10	EUCTR2019-002625-29-PL (EUCTR)	14/01/2020	21/11/2019	A trial to test how efficient Nabiximols is for treatment of spacticity in patients with Multiple Sc ...	A Randomized, Double-blind, Placebo-controlled, 2-way Crossover Trial to Evaluate the Effect of Nabi ...	Symptomatic treatment of spasticity in patients with multiple sclerosis (MS) MedDRA version: 20.0;Le ...	Trade Name: Sativex Oromucosal Spray Product Name: Nabiximols - Sativex INN or Proposed INN: Tetrahydr ...	GW Pharma Limited	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	52	Phase 3	Czechia;Czech Republic;Poland;United Kingdom

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36. 表皮水疱症

臨床試験数 : 163 / 薬物数 : 185 - (DrugBank : 46) / 標的遺伝子数 : 50 - 標的パスウェイ数 : 125

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2021-000103-20-NL (EUCTR)		15/07/2021	A study on the effect of Transvamix on pain in adults with epidermolysis bullosa.	An explorative randomized, placebo-controlled and double-blind intervention crossover study: Transva ...	Genetic Epidermolysis Bullosa;Therapeutic area: Diseases [C] - Symptoms and general pathology [C23]	Product Name: Transvamix (100mg/mL THC, 50mg/mL CBD) INN or Proposed INN: THC Other descriptive name: ...	University Medical Center Groningen	NULL	NA			Female: yes Male: yes	16	Phase 2	Netherlands

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298. 遺伝性膵炎

臨床試験数 : 95 / 薬物数 : 148 - (DrugBank : 51) / 標的遺伝子数 : 53 - 標的パスウェイ数 : 142

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01551511 (ClinicalTrials.gov)	October 2012	7/2/2012	?9-THC (Namisol®) in Chronic Pancreatitis Patients Suffering From Persistent Abdominal Pain	?9-THC (Namisol®) in Chronic Pancreatitis Patients Suffering From Persistent Abdominal Pain: a Rando ...	Pancreatitis, Chronic;Abdominal Pain;Chronic Pain	Drug: Tetrahydrocannabinol;Drug: Placebo	Radboud University	European Union	Completed	18 Years	N/A	Both	29	Phase 2	Netherlands
2	NCT01318369 (ClinicalTrials.gov)	October 2011	9/3/2011	Efficacy Study of ?9-THC to Treat Chronic Abdominal Pain	The Safety, Tolerability, and Analgesic Efficacy of ?9-THC (Namisol®) in Chronic Pancreatitis Patien ...	Cannabinoid;Tetrahydrocannabinol;Chronic Pancreatitis;Abdominal Pain	Drug: Namisol;Drug: Diazepam	Radboud University	NULL	Completed	18 Years	N/A	Both	24	Phase 2	Netherlands

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