MICROBIOTA ( DrugBank: - )

1 disease

告示番号	疾患名（ページ内リンク）	臨床試験数
96	クローン病	23

96. クローン病

臨床試験数 : 2,442 / 薬物数 : 1,278 - (DrugBank : 248) / 標的遺伝子数 : 142 - 標的パスウェイ数 : 209

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03747718 (ClinicalTrials.gov)	December 1, 2022	8/3/2018	Randomized Trial Comparing Single vs. Maintenance Fecal MicrobiotaTransplant for Refractory Crohn's ...	A Study for Evaluation of Clinical Response to Single vs. Maintenance Fecal MicrobiotaTransplantatio ...	Crohn Disease	Biological: Fecal Microbiota Transplantation;Other: Placebo	Stanford University	NULL	Not yet recruiting	2 Years	25 Years	All	30	Phase 1	United States
2	NCT05248191 (ClinicalTrials.gov)	April 20, 2022	9/2/2022	FMT for Postop Crohn's Disease	Fecal Microbiota Transplant for Postoperative Crohn's Disease	Crohn Disease	Biological: Capsule fecal microbiotamaterial (cap-FMT);Biological: Colonoscopic fecal microbiotamate ...	University of Minnesota	NULL	Recruiting	18 Years	N/A	All	30	Phase 1	United States
3	NCT04924270 (ClinicalTrials.gov)	January 2022	7/6/2021	Safety and Efficacy of Faecal MicrobiotaTransplantation in Treatment-naïve Patients With Newly Diagn ...	Safety and Clinical Efficacy Associated With Faecal MicrobiotaTransplantation Performed in Treatment ...	Rheumatoid Arthritis;Reactive Arthritis;Ankylosing Spondylitis;Psoriatic Arthritis;Gouty Arthritis;P ...	Biological: Faecal microbiota transplantation;Other: Placebo	Torkell Ellingsen	Region of Southern Denmark;University of Southern Denmark	Not yet recruiting	18 Years	70 Years	All	200	Phase 2	NULL
4	NCT04970446 (ClinicalTrials.gov)	August 1, 2021	18/7/2021	The MIRO II Study: Microbial Restoration in Inflammatory Bowel Diseases	The MIRO II Study: Microbial Restoration in Inflammatory Bowel Diseases	Fecal Microbiota Transplantation;Crohn Disease;Inflammatory Bowel Diseases;Microbiome	Drug: Antibiotics;Dietary Supplement: Dietician designed diet;Drug: FMT;Other: Placebo	St Vincent's Hospital Melbourne	The Queen Elizabeth Hospital;BiomeBank Adelaide;The University of Queensland;Monash University	Not yet recruiting	18 Years	70 Years	All	120	Phase 2/Phase 3	NULL
5	NCT05386290 (ClinicalTrials.gov)	July 9, 2020	17/5/2022	A Multicentered Prospective Cohort Study of Chinese IBD Patients	A Multicentered Prospective Cohort Study of Chinese IBD Patients Concerning Cost-effectiveness Analy ...	Ulcerative Colitis;Crohn Disease	Drug: Infliximab;Drug: Vedolizumab;Drug: Ustekinumab;Drug: conventional treatment (glucocoticoid, im ...	Peking Union Medical College Hospital	NULL	Enrolling by invitation	14 Years	80 Years	All	200		China
6	NCT05321758 (ClinicalTrials.gov)	March 22, 2020	4/4/2022	Fecal Microbiota Transplantation as the First-line Treatment in Active Pediatric Crohn's Disease	Repeated and Multiple Fecal MicrobiotaTransplantations Plus Partial Enteral Nutrition as the First-l ...	Crohn Disease	Biological: Fecal Microbiota Transplantation;Other: PEN	Tongji Hospital	NULL	Recruiting	2 Years	16 Years	All	50	N/A	China
7	EUCTR2019-003816-29-FR (EUCTR)	16/12/2019	14/10/2019	Fecal microbiota transplantation in Crohn’s disease as relay after anti-TNF withdrawal	Fecal microbiota transplantation in Crohn’s disease as relay after anti-TNF withdrawal - MIRACLE	Adult patients with Crohn’s disease diagnosed for at least 6 months and healthy volunteers donors Me ...	Product Name: Fecal microbiota Product Name: Fecal microbiota	ASSISTANCE PUBLIQUE -HOPITAUX DE PARIS (AP-HP)	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	200	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	France
8	NCT03378167 (ClinicalTrials.gov)	December 1, 2018	12/12/2017	PediCRaFT: Pediatric Crohn's Disease Fecal Transplant Trial	PediCRaFT: Pediatric Crohn's Disease Fecal Microbiota Transplant Pilot Study	Crohn Disease;Pediatric Crohns Disease;Inflammatory Bowel Diseases;Colitis	Biological: MICROBIOTA;Biological: PLACEBO	McMaster Children's Hospital	McMaster Children's Hospital (McMaster University);Centre Hospitalier Universitaire Sainte-Justine ( ...	Recruiting	3 Years	17 Years	All	45	Phase 1	Canada
9	NCT03476317 (ClinicalTrials.gov)	July 12, 2018	8/1/2018	Pilot Study of Fundamental Modification of the Gut Microbiotain the Treatment of Refractory Crohn's ...	An Open-Label Pilot Study of Fundamental Modification of the Gut Microbiotain the Treatment of Refra ...	Crohn Disease	Drug: Vancomycin;Drug: Neomycin;Drug: Ciprofloxacin;Drug: Polyethylene Glycol 3350;Drug: Fluconazole ...	Children's Hospital of Philadelphia	University of Pennsylvania;National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Completed	6 Years	N/A	All	10	Phase 2	United States
10	NCT03477032 (ClinicalTrials.gov)	June 1, 2018	19/3/2018	FMT in Inflammatory Bowel Disease	Faecal Transplantation in Inflammatory Bowel Disease	Faecal Microbiota Transplantation;Crohn Disease;Ulcerative Colitis;Microscopic Colitis	Biological: Faecal Microbiota Transplantation	St Vincent's Hospital Melbourne	NULL	Recruiting	18 Years	65 Years	All	50		Australia

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