Pentoxifylline ( DrugBank: Pentoxifylline )

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12 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
26	HTLV-1関連脊髄症	1
56	ベーチェット病	2
84	サルコイドーシス	1
86	肺動脈性肺高血圧症	1
93	原発性胆汁性胆管炎	1
96	クローン病	1
97	潰瘍性大腸炎	2
113	筋ジストロフィー	2
220	急速進行性糸球体腎炎	1
222	一次性ネフローゼ症候群	1
296	胆道閉鎖症	1
298	遺伝性膵炎	1

26. HTLV-1関連脊髄症

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臨床試験数 : 29 /  薬物数 : 47 - (DrugBank : 29) / 標的遺伝子数 : 34 - 標的パスウェイ数 : 119

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01472263 (ClinicalTrials.gov)	September 2009	11/11/2011	Use of Pentoxifylline in Human T-lymphotropic Virus Type-1 (HTLV-1) Diseases	Effectiveness of Pentoxifylline in Attenuating Neurological Disease Associated With HTLV-1 and Negative Modulator of Pathological Immune Response.	HTLV-1;Tropical Spastic Paraparesis;Immune System Diseases;Physical Disability;Pentoxifylline	Drug: Pentoxifylline;Drug: Placebo	Hospital Universitário Professor Edgard Santos	NULL	Completed	18 Years	80 Years	Both	48	Phase 3	Brazil

56. ベーチェット病

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臨床試験数 : 81 /  薬物数 : 107 - (DrugBank : 30) / 標的遺伝子数 : 36 - 標的パスウェイ数 : 116

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04186559 (ClinicalTrials.gov)	February 2020	2/12/2019	Topical Pentoxifylline Gel on Behcet's Disease Genital Ulcers	Clinical Protocol to Evaluate Use of Topical Pentoxifylline Gel on Behcet's Disease Genital Ulcers	Behcet Syndrome;Behcet Disease	Drug: Topical Pentoxifylline Gel (Vehicle +PTX);Drug: Topical Placebo Gel (Vehicle)	Silk Road Therapies, Inc.	NULL	Not yet recruiting	18 Years	N/A	All	60	Phase 2	United States
2	NCT03888846 (ClinicalTrials.gov)	March 25, 2019	21/3/2019	Topical Pentoxifylline Gel on Behcet's Disease Oral Ulcers	Clinical Protocol for Administration of Topical Pentoxifylline Gel on Behcet's Disease Oral Ulcers	Behçet Disease Affecting Oral Mucosa	Drug: Pentoxifylline;Drug: Colchicine	Ipekyolu Ilac Ltd. Sti	Istanbul University-Cerrahpasa School of Medicine	Recruiting	18 Years	N/A	All	60	Phase 2	Turkey

84. サルコイドーシス

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臨床試験数 : 149 /  薬物数 : 202 - (DrugBank : 78) / 標的遺伝子数 : 66 - 標的パスウェイ数 : 169

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00001877 (ClinicalTrials.gov)	February 1999	3/11/1999	Treatment of Pulmonary Sarcoidosis With Pentoxifylline	Treatment of Pulmonary Sarcoidosis With Pentoxifylline	Pulmonary Sarcoidosis	Drug: Pentoxifylline	National Heart, Lung, and Blood Institute (NHLBI)	NULL	Completed	N/A	N/A	Both	100	Phase 2	United States

86. 肺動脈性肺高血圧症

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臨床試験数 : 1,205 /  薬物数 : 684 - (DrugBank : 124) / 標的遺伝子数 : 100 - 標的パスウェイ数 : 193

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05611268 (ClinicalTrials.gov)	June 3, 2022	24/8/2022	Pentoxifylline as an Adjunct Therapy for Patients With Eisenmenger Syndrome	Pentoxifylline as an Adjunct Therapy for Patients With Eisenmenger Syndrome: a Randomized Study	Eisenmenger Syndrome	Drug: Pentoxifylline	University of Sao Paulo General Hospital	InCor Heart Institute	Recruiting	10 Years	80 Years	All	48	N/A	Brazil

93. 原発性胆汁性胆管炎

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臨床試験数 : 298 /  薬物数 : 252 - (DrugBank : 59) / 標的遺伝子数 : 35 - 標的パスウェイ数 : 115

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01249092 (ClinicalTrials.gov)	November 2010	24/11/2010	Pentoxifylline for Primary Biliary Cirrhosis	A Pilot Study of Pentoxifylline for the Treatment of Primary Biliary Cirrhosis	Primary Biliary Cirrhosis	Drug: Pentoxifylline	The Cleveland Clinic	NULL	Completed	18 Years	76 Years	All	20	Phase 2	United States

96. クローン病

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臨床試験数 : 2,442 /  薬物数 : 1,278 - (DrugBank : 248) / 標的遺伝子数 : 142 - 標的パスウェイ数 : 209

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02953275 (ClinicalTrials.gov)	April 13, 2017	31/10/2016	Synergistic Effect of Vedolizumab and Pentoxifylline	Synergistic Effect of Vedolizumab and Pentoxifylline in the Management of Patients With Inflammatory Bowel Disease	Crohn Disease	Drug: vedolizumab;Drug: Pentoxifylline;Drug: placebo	University of Miami	Takeda	Completed	18 Years	80 Years	All	37	Early Phase 1	United States

97. 潰瘍性大腸炎

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臨床試験数 : 2,630 /  薬物数 : 1,459 - (DrugBank : 265) / 標的遺伝子数 : 144 - 標的パスウェイ数 : 202

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05575505 (ClinicalTrials.gov)	February 2, 2023	8/10/2022	Phosphodiesterase Inhibitors, Pentoxifylline, as Adjunctive Therapy in Patients With Ulcerative Colitis.	Phosphodiesterase Inhibitors, Pentoxifylline, as Adjunctive Therapy in Patients With Ulcerative Colitis.	Inflammatory Bowel Diseases	Drug: Pentoxifylline 400 MG	Tanta University	NULL	Recruiting	18 Years	75 Years	All	44	Phase 2	Egypt
2	NCT05558761 (ClinicalTrials.gov)	October 10, 2022	25/9/2022	Pentoxifylline as Adjunctive Therapy in Patients With Ulcerative Colitis	Clinical Study to Evaluate the Possible Efficacy of Pentoxifylline in Patients With Ulcerative Colitis Treated With Mesalamine	Inflammatory Bowel Diseases	Drug: Pentoxifylline 400 MG	Tanta University	NULL	Recruiting	18 Years	75 Years	All	50	Phase 2	Egypt

113. 筋ジストロフィー

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臨床試験数 : 646 /  薬物数 : 471 - (DrugBank : 105) / 標的遺伝子数 : 59 - 標的パスウェイ数 : 170

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00243789 (ClinicalTrials.gov)	September 2005	21/10/2005	Study of Daily Pentoxifylline as a Rescue Treatment in Duchenne Muscular Dystrophy	A Double-Blinded Randomized Placebo Controlled Study of Daily Pentoxifylline as a Rescue Treatment in DMD	Muscular Dystrophy, Duchenne	Drug: Pentoxifylline	Cooperative International Neuromuscular Research Group	NULL	Completed	7 Years	N/A	Male	64	Phase 1/Phase 2	United States;Argentina;Australia;Canada;Israel;Italy
2	NCT00102453 (ClinicalTrials.gov)	March 2002	29/1/2005	Pentoxifylline in Duchenne Muscular Dystrophy	An Open-Label Pilot Study of Pentoxifylline in Steroid-naive Duchenne Muscular Dystrophy	Muscular Dystrophy, Duchenne	Drug: Pentoxifylline	Cooperative International Neuromuscular Research Group	NULL	Completed	4 Years	7 Years	Male	17	Phase 1/Phase 2	United States

220. 急速進行性糸球体腎炎

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臨床試験数 : 2 /  薬物数 : 4 - (DrugBank : 2) / 標的遺伝子数 : 1 - 標的パスウェイ数 : 1

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00354198 (ClinicalTrials.gov)	August 2006	18/7/2006	Efficacy of Pentoxifylline on Rapidly Progressive Glomerulonephritis	Clinical Efficacy of Combined Pentoxifylline and Conventional Immunosuppressive Regimens on Patients With Rapidly Progressive Glomerulonephritis	Glomerulonephritis	Drug: pentoxifylline;Drug: corticosteroids	National Taiwan University Hospital	National Science Council, Taiwan	Terminated	20 Years	80 Years	Both	7	Phase 3	Taiwan

222. 一次性ネフローゼ症候群

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臨床試験数 : 310 /  薬物数 : 295 - (DrugBank : 117) / 標的遺伝子数 : 63 - 標的パスウェイ数 : 194

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00354731 (ClinicalTrials.gov)	August 2006	18/7/2006	Efficacy of Pentoxifylline on Primary Nephrotic Syndrome	Clinical Efficacy of Pentoxifylline on Patients With Primary Nephrotic Syndrome	Nephrotic Syndrome	Drug: pentoxifylline;Drug: Corticosteroid	National Taiwan University Hospital	National Science Council, Taiwan	Completed	20 Years	80 Years	Both	62	Phase 3	Taiwan

296. 胆道閉鎖症

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臨床試験数 : 71 /  薬物数 : 70 - (DrugBank : 39) / 標的遺伝子数 : 35 - 標的パスウェイ数 : 60

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01774487 (ClinicalTrials.gov)	February 4, 2013	22/1/2013	Pentoxifylline Therapy in Biliary Atresia	A Phase II Trial of Pentoxifylline in Newly-Diagnosed Biliary Atresia	Biliary Atresia	Drug: Pentoxifylline	Baylor College of Medicine	NULL	Terminated	N/A	180 Days	All	17	Phase 2	United States

298. 遺伝性膵炎

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臨床試験数 : 95 /  薬物数 : 148 - (DrugBank : 51) / 標的遺伝子数 : 53 - 標的パスウェイ数 : 142

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02487225 (ClinicalTrials.gov)	May 2015	29/6/2015	Pentoxifylline Treatment in Acute Pancreatitis (AP)	Pentoxifylline Treatment in Acute Pancreatitis: A Double-Blind Placebo - Controlled Randomized Trial	Acute Pancreatitis (AP);Gallstone Pancreatitis;Alcoholic Pancreatitis;Trauma Acute Pancreatitis;Hypertriglyceridemia Acute Pancreatitis;Idiopathic (Unknown) Acute Pancreatitis;Medication Induced Acute Pancreatitis;Cancer Acute Pancreatitis;Miscellaneous (i.e. Acute on Chronic Pancreatitis)	Drug: Pentoxifylline;Drug: Placebo	Mayo Clinic	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Completed	18 Years	100 Years	All	83	Phase 3	United States

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