Vitamin D ( DrugBank: Vitamin D )


5 diseases
告示番号疾患名(ページ内リンク)臨床試験数
46悪性関節リウマチ19
49全身性エリテマトーデス10
96クローン病35
97潰瘍性大腸炎13
299嚢胞性線維症16

46. 悪性関節リウマチ


臨床試験数 : 4,356 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04909931
(ClinicalTrials.gov)
June 15, 202111/5/2021Vitamin D Supplementation on Outcome and Disease Activity.Vitamin D Supplementation on Outcome and Disease Activity in Rheumatoid Arthritis Patients at Rajavithi Hospital : A Randomized Clinical TrialRheumatoid Arthritis, Vitamin D , Disease Activity, DAS28ESRDrug: Vitamin D 2;Drug: PlaceboRajavithi HospitalNULLRecruiting18 YearsN/AAll60N/AThailand
2NCT05078502
(ClinicalTrials.gov)
June 1, 20214/10/2021Role of Vitamin D3 Supplementation With Conventional Synthetic Disease Modifying Antirheumatic Drugs(csDMARD) in Rheumatoid Arthritis PatientsRole of Vitamin D3 Supplementation With Conventional Synthetic Disease Modifying Antirheumatic Drugs (csDMARD) in Rheumatoid Arthritis Patients: Randomized Double-blind Placebo Controlled TrialRheumatoid ArthritisDietary Supplement: Vitamin D3Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshNULLCompleted18 Years70 YearsAll58N/ABangladesh
3NCT04472481
(ClinicalTrials.gov)
September 6, 20197/7/2020Vitamin D Effect in Rheumatoid Arthritis.Vitamin D: Does It Help Tregs in Active Rheumatoid Arthritis Patients.Active Rheumatoid ArthritisDrug: Ergocalciferol 1.25 mg tabletTanta UniversityNULLCompleted33 Years60 YearsAll20Phase 4Egypt
4NCT04344405
(ClinicalTrials.gov)
June 1, 20199/4/2020Vitamin D as a Key Player in Rheumatoid ArthritisVitamin D as a Key Player in Rheumatoid Arthritis Immune Responsethe Immunomodulatory EffectDrug: Vitamin D;Drug: Steroid DrugAssiut UniversityNULLCompleted20 Years70 YearsAll40Phase 3Egypt
5JPRN-UMIN000030828
2018/01/1515/01/2018The preventive effect for new vertebral fractures of zoledronic acid and denosumab combined with vitamin D in patients with rheumatoid arthritis.The preventive effect for new vertebral fractures of zoledronic acid and denosumab combined with vitamin D in patients with rheumatoid arthritis. - EVIDENCE study Rheumatoid ArthritisOsteoporosiszoledronic acid
denosumab
Osaka City University Graduate School of MedicineNULLRecruiting20years-oldNot applicableMale and Female500Not selectedJapan
6JPRN-UMIN000022364
2016/05/1020/05/2016Treatment strategy of minodronate in osteoporotic patients with rheumatoid arthritisTreatment strategy of minodronate in osteoporotic patients with rheumatoid arthritis - Effectiveness of minodronate in osteoporotic patients with rheumatoid arthritis Osteoprotic patients with rheumatoid arthritisThe selection criteria is based on which treatment each patient wants to take
Minodronate group: oral intake 50mg per month
Minodronate plus active vitamin D group: oral intake 50mg minodronate per month and eldecalcitol 0.75ug per day after breakfast
Department of Orthopaedic Surgery Shinshu University School of MedicineNULLComplete: follow-up complete50years-old100years-oldMale and Female140Not applicableJapan
7NCT02944799
(ClinicalTrials.gov)
December 201527/6/2016Alendronate Treatment of Osteoporosis in Rheumatoid ArthritisAlendronate Treatment of Osteoporosis in Rheumatoid Arthritis - Indication and Duration: A Randomized, Double-blind, Placebocontrolled Study to Evaluate the Effects of Discontinuation of Alendronate in Patients With Both Rheumatoid Arthritis and Low Bone MassRheumatoid Arthritis;OsteoporosisDrug: Placebo;Drug: Alendronate;Drug: Calcium;Drug: Vitamin DUniversity of AarhusNULLActive, not recruiting18 YearsN/AAll69Phase 2Denmark
8NCT02633332
(ClinicalTrials.gov)
February 201530/11/2015Use of Well Known Drugs for New Destination - RA Improvement (RANT)Observational Retrospective Study About the Use of Well Known Drugs in Combination to Obtain a New Drug to Improve Quality of Life/Health in Patient With Diagnosed Rheumatoid Arthritis Not Responding to Commonly Used TreatmentsRheumatoid Arthritis;Autoimmune Diseases;Disorder of Synovium;Sjogren's Syndrome;Acute and Chronic Inflammation;Disorder of Pleura and Pleural Cavity;Felty's Syndrome;Rheumatoid NodulesDrug: Vitamin D3;Drug: Lipitor®;Drug: Acycloguanosine;Drug: Tetracycline;Drug: methotrexate;Drug: etanerceptUniversità Popolare Homo & NaturaNULLCompleted18 Years75 YearsBoth15Phase 1Italy
9JPRN-UMIN000014737
2014/08/0101/08/2014The effects of denosumab compared with oral bisphosphonates (BP) in patients with RA complicated with osteoporosis on the progression of structural damage, BMD and disease activity.The effects of denosumab compared with oral bisphosphonates (BP) in patients with RA complicated with osteoporosis on the progression of structural damage, BMD and disease activity. - Two Birds trial rheumatoid arthritisDenosumab group: Denosumab 60mg is administered by subcutaneous injections every 6 months (at baseline, at 6 months and at 12 months). All patients are to take vitamin D.
BP group: Patients take BP continuously. All patients are to take vitamin D.
Yokohama City University Medical CenterNULLComplete: follow-up complete50years-old90years-oldMale and Female286Not selectedJapan
10NCT01400516
(ClinicalTrials.gov)
August 201121/7/2011Teriparatide for Joint Erosions in Rheumatoid Arthritis: The TERA TrialTeriparatide for Joint Erosions in Rheumatoid Arthritis: The TERA TrialRheumatoid ArthritisDrug: Teriparatide;Drug: calcium citrate;Drug: Vitamin D;Drug: TNF antagonistBrigham and Women's HospitalEli Lilly and CompanyCompleted45 YearsN/AAll26Phase 4United States
11EUCTR2009-012615-18-FR
(EUCTR)
16/02/201105/11/2010Efficacy and safety of cholecalciferol on rheumatoid arthritis activity in patients with vitamin D deficiency - SCORPIONEfficacy and safety of cholecalciferol on rheumatoid arthritis activity in patients with vitamin D deficiency - SCORPION Rheumatoid arthritis (RA)
MedDRA version: 12.1;Level: HLT;Classification code 10039075;Term: Rheumatoid arthritis and associated conditions
Trade Name: UVEDOSE
INN or Proposed INN: COLECALCIFEROL
CHU de Clermont-FerrandNULLNot RecruitingFemale: yes
Male: yes
France
12NCT01351805
(ClinicalTrials.gov)
January 20114/5/2011Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Knee PainVitamin D and Fish Oil for Autoimmune Disease, Inflammation and Knee PainAutoimmune Diseases;Systemic Inflammatory Process;Knee Pain Chronic;Osteoarthritis;Rheumatoid ArthritisDrug: Fish Oil;Dietary Supplement: Vitamin D;Other: placebo pillBrigham and Women's HospitalNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)Active, not recruiting50 YearsN/AAll25876N/AUnited States
13EUCTR2009-015835-34-IT
(EUCTR)
09/04/201029/03/2010VITAMIN D EFFECT ON T LYMPHOCYTES AND OSTEOCLASTOGENESIS IN RHEUMAOID ARTHRITIS - NDVITAMIN D EFFECT ON T LYMPHOCYTES AND OSTEOCLASTOGENESIS IN RHEUMAOID ARTHRITIS - ND Rheumatoid Arthritis
MedDRA version: 12.1;Level: LLT;Classification code 10003268;Term: Arthritis rheumatoid
Trade Name: DIBASE*IM OS 2F 1ML 300000UI/M
INN or Proposed INN: Colecalciferol
AZIENDA OSPEDALIERA ORDINE MAURIZIANONULLNot RecruitingFemale: yes
Male: no
Phase 3Italy
14NCT00279461
(ClinicalTrials.gov)
May 200917/1/2006Vitamin D Deficiency Causes Immune Dysfunction and Enables or Perpetuates the Development of Rheumatoid ArthritisVitamin D Deficiency Causes Immune Dysfunction and Enables or Perpetuates the Development of Rheumatoid Arthritis: Clinical Trial and Investigations on Dendritic CellsArthritis, Rheumatoid;Vitamin D DeficiencyDrug: Placebo in arm A and Vitamin D in arm B;Drug: vitamin D 3 for arm A ,and matching placebo for arm BIndiana UniversityNULLWithdrawn18 YearsN/ABoth0Phase 2United States
15NCT01426347
(ClinicalTrials.gov)
January 200929/8/2011Treatment of Vitamin D Deficiency in Patients With Rheumatoid ArthritisVitamin Therapy in Rheumatoid ArthritisRheumatoid Arthritis;Vitamin D DeficiencyDrug: Placebo sugar pill;Drug: ErgocalciferolJohns Hopkins UniversityNULLCompleted18 Years75 YearsAll139N/AUnited States
16NCT00427804
(ClinicalTrials.gov)
January 200725/1/2007Tumor Necrosis Factor Decreases Vitamin D Dependant Calcium AbsorptionTumor Necrosis Factor-a Induces Vitamin D Resistance in Small Intestinal Calcium AbsorptionRheumatoid Arthritis;Crohn's DiseaseDrug: calcitriolAtlanta VA Medical CenterEmory UniversityCompleted18 Years50 YearsMale9N/AUnited States
17NCT00423358
(ClinicalTrials.gov)
February 200517/1/2007Treatment of Hypovitaminosis D in Rheumatoid ArthritisTreatment of Hypovitaminosis D in Rheumatoid ArthritisRheumatoid Arthritis;Hypovitaminosis DDietary Supplement: Vitamin D;Dietary Supplement: placeboUniversity of Wisconsin, MadisonNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)Completed18 Years90 YearsAll22N/AUnited States
18NCT00138983
(ClinicalTrials.gov)
May 200029/8/2005Prevention of Glucocorticoid-Induced Osteoporosis in Rheumatic Diseases: Alendronate Versus Alfacalcidol.Prevention of Glucocorticoid-Induced Osteoporosis in Patients With Rheumatic Diseases. The STOP-Study: a Randomized Placebo Controlled Trial With Alendronate Versus Alfacalcidol.Rheumatoid Arthritis;Polymyalgia Rheumatica;Giant Cell Arteritis;Polymyositis;Wegener’s GranulomatosisDrug: Alendronate versus alfacalcidol (1-alpha OH vitamin D)UMC UtrechtDutch Health Care Insurance BoardCompleted18 Years90 YearsBoth200Phase 3Netherlands
19NCT00570934
(ClinicalTrials.gov)
March 19957/12/2007Supplementation With Vitamin D, Calcium or Both on Calcium Absorption and Bone Mineral Content in Children With JRAEffect of Supplementation With 2000 International Units (IU) Vitamin D, 1gm Calcium or Both on Calcium Absorption and Bone Mineralization in Children With Juvenile Rheumatoid ArthritisJuvenile Rheumatoid ArthritisDietary Supplement: Cholecalciferol;Dietary Supplement: Calcium;Dietary Supplement: Calcium and cholecalciferol;Drug: PlaceboUniversity of Missouri-ColumbiaNULLCompleted3 Years15 YearsBoth24Phase 3United States

49. 全身性エリテマトーデス


臨床試験数 : 993 薬物数 : 702 - (DrugBank : 184) / 標的遺伝子数 : 116 - 標的パスウェイ数 : 200
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT05326841
(ClinicalTrials.gov)
October 3, 202123/3/2022Effect of Cholecalciferol Supplementation on Disease Activity and Quality of Life of Systemic Lupus Erythematosus Patients .Effect of Cholecalciferol Supplementation on Disease Activity and Quality of Life of Systemic Lupus Erythematosus PatientsLupus Erythematosus, Systemic;Cholecalciferol Supplementation;Disease Activity;Quality of LifeDrug: Vitamin D3Dr Cipto Mangunkusumo General HospitalNULLCompleted18 Years60 YearsFemale60Phase 3Indonesia
2NCT05260255
(ClinicalTrials.gov)
June 15, 202112/5/2021Effect of Vitamin D Supplement on Disease Activity in SLEThe Effect of Vitamin D Supplementation on Disease Activity of Systemic Lupus Erythematosus Patients: A Randomized Clinical Trial in Rajavithi HospitalVitamin D Deficiency;Hypocalcemia;Hyperparathyroidism;Systemic Lupus Erythematosus (Disorder)Drug: vitamin D2 ( calciferol );Drug: PlaceboRajavithi HospitalNULLRecruiting18 YearsN/AAll100N/AThailand
3ChiCTR-INR-17011495
2017-05-252017-05-26Canceled by the investigator The efficacy and safety of metformin hydrochloride combined with atorvastatin in the treatment of primary mild to moderate systemic syThe efficacy and safety of metformin hydrochloride combined with atorvastatin in the treatment of primary mild to moderate systemic systemic lupus erythematosus Primary mild to moderate systemic systemic lupus erythematosusImmunomodulatory treatment group:The level of SELSNA-SLEDAI was evaluated at week 4, week 12 and week 24, the BILAG table, the SLE lesion index, and the SLE damage index were measured at 4 weeks, 12 weeks and 24 weeks. The levels of Th17, Treg and Th17 / Treg were measured.;Leflunomide treatment group:Leflunomide tablets 10m, 1 times / day, orally. The SELSNA-SLEDAI score table, BILAG worksheet, SLE damage index score were assessed at week 4, week 12 and week 24, and serum Th17, Treg and Th17 / Treg ratios were measured.;Immunomodulatory treatment group and Leflunomide treatment group :0 weeks to give prednisone acetate tablets 0.5-1mg / kg.d (or patients can choose to take the same dose of methylprednisolone tablets), 4 weeks after the beginning of the dose by 2 weeks to reduce the regular dose of 10% Reduction to prednisone acetate tablets 10mg / day to maintain.;Immunomodulatory treatment group and Leflunomide treatment group:All patients without contraindications plus hydroxychloroquine tablets 0.2,2 / day, orally; and according to the condition plus calcium (800-1200mg / day), vitamin D (200-800IU / day) and other treatment.;The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and TechnologyNULLRecruitingBothImmunomodulatory treatment group:15;Leflunomide treatment group:15;Immunomodulatory treatment group and Leflunomide treatment group :30;Immunomodulatory treatment group and Leflunomide treatment group:30;China
4NCT03155477
(ClinicalTrials.gov)
June 10, 201613/5/2017Effect Of Curcuma Xanthorrhiza and Vitamin D3 Supplementation in SLE Patients With Hypovitamin DEffect Of Curcuma Xanthorrhiza Supplementation In Systemic Lupus Erythematosus Patients (SLE) With Hypovitamin D Which Were Given Vitamin D3 Towards Disease Activity (SLEDAI), Interleukin-6 (IL-6) And Tumor Growth Factor-ß1 (TGF-ß1) SerumSLEDietary Supplement: Cholecalciferol and C. Xanthorrhiza;Dietary Supplement: Cholecalciferol and placeboSaiful Anwar HospitalNULLCompleted18 Years45 YearsFemale39N/ANULL
5NCT01709474
(ClinicalTrials.gov)
June 201316/10/2012Vitamin D3 Treatment in Pediatric Systemic Lupus ErythematosusVitamin D3 Effects on Immune Function in Pediatric Systemic Lupus Erythematosus (SLE)Systemic Lupus ErythematosusDrug: Vitamin D3 6000 IU;Drug: Vitamin D3 400 IUNational Institute of Allergy and Infectious Diseases (NIAID)Autoimmunity Centers of ExcellenceTerminated5 Years20 YearsAll7Phase 2United States
6NCT01911169
(ClinicalTrials.gov)
June 201122/7/2013Vitamin D to Improve Endothelial Function in SLEVitamin D Repletion to Improve Endothelial Function in Lupus PatientsAtherosclerosis;Systemic Lupus ErythematosusDrug: CholecalciferolMedical University of South CarolinaNULLCompleted18 Years80 YearsAll9Phase 2United States
7NCT01425775
(ClinicalTrials.gov)
April 201018/8/2011The Effect of Vitamin D Supplementation on Disease Activity Markers in Systemic Lupus Erythematosus (SLE)Systemic Lupus ErythematosusDrug: vitamin D 25(OH)D;Other: PlaceboFaculty of Medicine, University of AlexandriaNULLCompleted18 Years60 YearsBoth248N/AEgypt
8NCT01413230
(ClinicalTrials.gov)
January 201024/6/2011Vitamin D Supplementation in Systemic Lupus ErythematosusEvaluation of Immunologic Response After Vitamin D Supplementation in Patients With Systemic Lupus ErythematosusVitamin D DeficiencyDrug: cholecalciferolAssistance Publique - Hôpitaux de ParisNULLCompleted18 YearsN/ABoth20N/AFrance
9NCT00710021
(ClinicalTrials.gov)
November 20081/7/2008Vitamin D3 in Systemic Lupus ErythematosusEffect of Vitamin D3 on the IFN Alpha Signature in Patients With Systemic Lupus Erythematosus (ALE02)Systemic Lupus Erythematosus;SLE;LupusDrug: Vitamin D3;Drug: Vitamin D3 placeboNational Institute of Allergy and Infectious Diseases (NIAID)Autoimmunity Centers of ExcellenceCompleted18 YearsN/AAll57Phase 2United States
10NCT00418587
(ClinicalTrials.gov)
December 20064/1/2007Vitamin D Therapy in Patients With Systemic Lupus Erythematosus (SLE)Phase 1 Study of Vitamin D Therapy in Patients With Systemic Lupus Erythematosus (SLE)Systemic Lupus ErythematosusDrug: CholecalciferolMedical University of South CarolinaAmerican College of Rheumatology Research and Education Foundation;National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)Completed18 Years85 YearsAll18Phase 1United States

96. クローン病


臨床試験数 : 2,442 薬物数 : 1,278 - (DrugBank : 248) / 標的遺伝子数 : 142 - 標的パスウェイ数 : 209
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04991324
(ClinicalTrials.gov)
September 21, 202227/7/2021Cholecalciferol Comedication in IBD - the 5C-studyCholecalciferol Comedication in Patients With Chronic Inflammatory Bowel Diseases (Crohn's Disease or Ulcerative Colitis) - the 5C-studyInflammatory Bowel DiseasesDrug: Vitamin D3University Hospital, Basel, SwitzerlandNULLRecruiting18 YearsN/AAll150Phase 3Switzerland
2NCT04828031
(ClinicalTrials.gov)
July 1, 202129/3/2021Vitamin D Regulation of Gut Specific B Cells and Antibodies Targeting Gut Bacteria in Inflammatory Bowel DiseaseVitamin D Regulation of a4ß7+ B Cell Immunophenotypes and Mucosal Antibody Response to Commensal Gut Bacteria in Patients With Inflammatory Bowel DiseaseCrohn Disease;Inflammatory Bowel Diseases;Ulcerative ColitisDrug: Vitamin DStanford UniversityDoris Duke Charitable FoundationRecruiting18 YearsN/AAll50Phase 1United States
3NCT04225819
(ClinicalTrials.gov)
October 1, 20203/1/2020Adjunctive Treatment With Vitamin D3 in Patients With Active IBDAdjunctive Treatment With Vitamin D3 in Patients With Active IBD (ACTIVATED): A Randomized, Double-blind, Placebo-controlled TrialIBD;Inflammatory Bowel Diseases;Crohn Disease;Ulcerative Colitis;Vitamin D3 DeficiencyDietary Supplement: Vitamin D3;Other: PlaceboMassachusetts General HospitalNULLRecruiting18 YearsN/AAll100N/AUnited States
4NCT04308850
(ClinicalTrials.gov)
October 202024/2/2020Exploring the Effects of Vitamin D Supplementation on the Chronic Course of Patients With Crohn's Disease With Vitamin D DeficiencyExploring the Effects of Vitamin D Supplementation on the Chronic Course of Patients With Crohn's Disease With Vitamin D Deficiency,a Prospective Cohort StudyCrohn's Disease;Vitamin D Deficiency;Vitamin D SupplementDrug: Vitamin D dropsSecond Affiliated Hospital of Wenzhou Medical UniversityNULLNot yet recruitingN/AN/AAll60Early Phase 1China
5NCT04276636
(ClinicalTrials.gov)
October 202017/2/2020Exploring the Effects of Caltrate Supplement on the Chronic Course of Crohn's Disease Patients With Vitamin D DeficiencyExploring the Effects of Caltrate Supplement on the Chronic Course of Crohn's Disease Patients With Vitamin D Deficiency,a Prospective Cohort StudyCrohn's Disease;Vitamin D Deficiency;Vitamin D SupplementDrug: Caltrate PillSecond Affiliated Hospital of Wenzhou Medical UniversityNULLNot yet recruitingN/AN/AAll60Early Phase 1China
6NCT03999580
(ClinicalTrials.gov)
February 7, 202024/6/2019The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 )A Pragmatic Randomized Controlled Trial on High Dose Vitamin D to Prevent Relapses of Crohn's Disease in ChildrenCrohn DiseaseDrug: vitamin D3Jantchou PrevostNULLRecruiting4 Years18 YearsAll316Phase 3Canada
7NCT04134065
(ClinicalTrials.gov)
December 1, 201917/10/2019the Effect of Vitamin D in Crohn's Diseasethe Effect of Target-oriented Vitamin D Treatment in Refractory Crohn's DiseaseVitamin D Deficiency;Crohn DiseaseDrug: Vitamin D;Drug: Placebo oral capsuleNanjing University School of MedicineShanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityNot yet recruiting20 Years60 YearsAll30Early Phase 1NULL
8NCT03718182
(ClinicalTrials.gov)
September 17, 201923/10/2018Can Vitamin D Supplementation in People With Crohn's Disease Improve Symptoms as an Adjunct Therapy?Can Vitamin D Supplementation in People With Crohn's Disease Improve Symptoms as an Adjunct Therapy? D-CODE Feasibility Randomised Controlled TrialCrohn Disease;Vitamin D DeficiencyDietary Supplement: CholecalciferolUniversity Hospital Birmingham NHS Foundation TrustNational Institute for Health Research, United Kingdom;University of Birmingham;Clinical Trials Research CentreRecruiting18 YearsN/AAll50Phase 4United Kingdom
9NCT03615378
(ClinicalTrials.gov)
August 30, 201816/7/2018Maintenance Dosing of Vitamin D in Crohn's DiseaseA Randomized, Double Blind, Placebo Controlled Trial Evaluating Optimal Maintenance Strategies of Vitamin D Levels in Patients With Crohn's Disease in RemissionCrohns Disease;Vitamin D DeficiencyDietary Supplement: 5000 IU D3;Dietary Supplement: 1000 IU D3;Dietary Supplement: PlaceboCedars-Sinai Medical CenterNULLTerminated18 YearsN/AAll10Early Phase 1United States
10ChiCTR1800015174
2018-05-012018-03-12Effects of Vitamin D supplementation on clinical prognosis for patients with Crohn's diseaseEffects of Vitamin D supplementation on clinical prognosis for patients with Crohn's disease Crohn's diseasecontrol group:placebo;Vitamin D:800IU Vitamin D;Gudangdong General Hospital, Guangdong Academy of Medical SciencesNULLPending1875Bothcontrol group:32;Vitamin D:32;China
11NCT02704624
(ClinicalTrials.gov)
December 201624/2/2016Effects of Supplementation of Vitamin D in Patients With Crohn's DiseaseThe Impact of Serum Vitamin D and Calcium Levels on the Body Composition, Bone Mineral Density, Muscle Strength, Exercise Tolerance, Fatigue and Inflammatory Activity in Patients With Crohn's Disease: a Randomized Controlled TrialCrohn Disease;Vitamin D Deficiency;Fatigue;Sarcopenia;Muscle Weakness;Disorder of Bone Density and Structure, UnspecifiedDietary Supplement: Vitamin D;Other: PlaceboFederal University of Juiz de ForaFundação de Amparo à Pesquisa do estado de Minas GeraisEnrolling by invitation18 Years50 YearsAll110Phase 4Brazil
12NCT02186275
(ClinicalTrials.gov)
February 20164/7/2014The Vitamin D in Pediatric Crohn's DiseaseRandomized Controlled Trial of High Dose Vitamin D in Children With Newly Diagnosed Crohn's Disease for the Prevention of RelapsesCrohn's DiseaseDrug: Vitamin D3: 3000 or 4000 UI/day then 2,000 UI/day;Drug: Vitamin D3 800 UI/day then 800 UI/daySt. Justine's HospitalCanadian Institutes of Health Research (CIHR)Completed9 Years18 YearsAll25Phase 3Canada
13NCT02208310
(ClinicalTrials.gov)
April 20151/8/2014Trial of High Dose Vitamin D in Patient's With Crohn's DiseaseA Randomized Controlled Trial of High-Dose Vitamin D in Crohn's DiseaseCrohn's Disease;Vitamin D DeficiencyDrug: Cholecalciferol 10,000 IU;Drug: Cholecalciferol 400 IUUniversity of MichiganCrohn's and Colitis FoundationTerminated18 Years75 YearsAll11Phase 4United States
14EUCTR2013-002838-20-BE
(EUCTR)
09/12/201415/09/2014The effect of Vitamin D to prevent post-operative relapse of Crohn's DiseaseThe effect of Vitamin D3 to prevent post-operative relapse of Crohn’s Disease: a placebo-controlled randomized trial (DETECT) - DETECT Crohn's Disease
MedDRA version: 19.0;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Trade Name: D-CURA
Product Name: D-Cura
INN or Proposed INN: Cholecalciferol
Other descriptive name: CHOLECALCIFEROL CONCENTRATE (WATER-DISPERSIBLE FORM)
Academic Medical CenterNULLNot RecruitingFemale: yes
Male: yes
142Phase 3Belgium;Netherlands
15NCT04606017
(ClinicalTrials.gov)
January 1, 201425/10/2020Effect of Vitamin D Supplementation on Infliximab Response in Patients With Crohn's DiseaseInfluence of Vitamin D3 Supplementation on Infliximab Efficacy in Chinese Patients With Crohn's Disease: A Retrospective Cohort StudyCrohn Disease;Vitamin D Deficiency;Vitamin D SupplementDrug: Caltrate PillSecond Affiliated Hospital of Wenzhou Medical UniversityNULLCompleted18 YearsN/AAll70China
16NCT02615288
(ClinicalTrials.gov)
January 201423/11/2015High Dose Vitamin D3 in Crohn's DiseaseImpact of High Dose Vitamin D3 Supplementation in Treatment of Crohn's Disease in Remission: A Randomized Double-blind Controlled StudyCrohn's DiseaseDietary Supplement: Vitamin D3McMaster UniversityCanadian Association of GastroenterologyCompleted18 Years70 YearsBoth40N/ANULL
17EUCTR2013-002838-20-NL
(EUCTR)
12/11/201306/09/2013The effect of Vitamin D to prevent post-operative relapse of Crohn's DiseaseThe effect of Vitamin D3 to prevent post-operative relapse of Crohn’s Disease: a placebo-controlled randomized trial (DETECT) - DETECT Crohn's Disease
MedDRA version: 18.0;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Trade Name: InVita D3
INN or Proposed INN: Colecalciferol
Other descriptive name: CHOLECALCIFEROL CONCENTRATE
Academic Medical CenterNULLNot RecruitingFemale: yes
Male: yes
142Phase 3Belgium;Netherlands
18EUCTR2013-000971-34-DK
(EUCTR)
01/08/201301/08/2013High dose vitamin D treatment in Crohn's disease affects the gut immune cellsMucosal immune regulation by high dose vitamin D treatment in Crohn’s disease - MirViDiC Active Crohn's Disease in colon and/or terminal ileum
MedDRA version: 19.0;Level: LLT;Classification code 10011408;Term: Crohns disease aggravated;System Organ Class: 100000004856 ;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Trade Name: Dekristol 20.000 ie
INN or Proposed INN: cholecalciferol
Other descriptive name: CHOLECALCIFEROL
Trade Name: Remicade
INN or Proposed INN: INFLIXIMAB
Trade Name: Remsima
INN or Proposed INN: INFLIXIMAB
Jørgen AgnholtNULLNot Recruiting Female: yes
Male: yes
50 Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (Phase 3): yes Therapeutic use (Phase 4): noDenmark
19NCT01864616
(ClinicalTrials.gov)
July 201322/5/2013The Impact of Vitamin D on Disease Activity in Crohn's DiseaseCrohn DiseaseDietary Supplement: Vitamin D3University of SaskatchewanDania Alrefai;Dr.Jennifer Jones;Dr.Hani Jawa;Dr.Wael El-matary;Saudi Arabian Cultural BureauTerminated16 Years70 YearsAll9N/ACanada;Saudi Arabia
20NCT02010762
(ClinicalTrials.gov)
February 201310/12/2013The Effect of Vitamin D3 to Maintain Surgical Remission in Postoperative Crohn's DiseaseThe Effect of Vitamin D3 to Maintain Surgical Remission in Postoperative Crohn's Disease: a Placebo-controlled Randomized TrialCrohn's DiseaseDrug: Vitamin D;Drug: PlaceboAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NULLCompleted18 YearsN/AAll142Phase 4Netherlands
21NCT01692808
(ClinicalTrials.gov)
October 201217/9/2012Bioavailability of Vitamin D in Children and Adolescents With Crohn's DiseaseBioavailability of Vitamin D in Children and Adolescents With Crohn's Disease.Crohn's DiseaseDrug: Vitamin D3 3000 UI daily;Drug: Vitamin D3 4000 UI dailySt. Justine's HospitalNULLCompleted10 Years18 YearsBoth20Phase 2Canada
22NCT01877577
(ClinicalTrials.gov)
April 201211/6/2013Supplementation of Vitamin D3 in Patients With Inflammatory Bowel Diseases and Hypovitaminosis DSupplementation of Vitamin D3 (Cholecalciferol) in Patients With Inflammatory Bowel Diseases (IBD) and Hypovitaminosis D: A Prospective Randomized Controlled Trial.Crohn's Disease (CD);Ulcerative Colitis (UC)Dietary Supplement: Vitamin D3University of California, San FranciscoNULLCompleted18 YearsN/ABoth30N/AUnited States
23NCT01369667
(ClinicalTrials.gov)
April 20127/6/2011Vitamin D Supplementation in Adult Crohn's DiseaseVitamin D and Immunomodulation: Effects in Crohn's DiseaseCrohn's DiseaseDietary Supplement: Vitamin D3;Other: PlaceboUniversity of Dublin, Trinity CollegeQueen Mary University of LondonCompleted18 Years75 YearsBoth117Phase 4Ireland
24NCT01792388
(ClinicalTrials.gov)
December 201119/12/2012Vitd and Barrier Function in IBDVitamin D and Its Effects on Inflammation and Intestinal Permeability in Crohn's Disease in RemissionCrohn's DiseaseDietary Supplement: Vitamin D;Dietary Supplement: Soya Bean oilUniversity of Dublin, Trinity CollegeUniversity of Calgary;Queen Mary University of LondonCompleted18 Years70 YearsBoth30Phase 4Ireland
25NCT01187459
(ClinicalTrials.gov)
September 201020/8/2010Vitamin D in Pediatric Crohn's DiseaseVitamin D in Pediatric Crohn's DiseaseVitamin D DeficiencyDietary Supplement: Vitamin DUniversity of British ColumbiaMcMaster UniversityCompleted8 Years18 YearsBoth87Phase 4Canada
26NCT01215890
(ClinicalTrials.gov)
September 20105/10/2010Risedronate Therapy in the Treatment of Low Bone Mineral Density in Crohn's DiseaseA Randomized, Data Collection Program To Determine the Efficacy and Safety of Risedronate (Actonel) Therapy Plus Calcium and Vitamin D Supplementation Versus Placebo Plus Calcium and Vitamin D Supplementation in the Treatment of Low Bone Mineral Density in Crohn's Disease PatientsCrohn's Disease;Low Bone Mineral DensityDrug: risedronate;Drug: placeboUniversity of AlbertaNULLCompleted18 YearsN/ABothPhase 4Canada
27NCT01046773
(ClinicalTrials.gov)
January 201011/1/2010Vitamin D Supplementation as Non-toxic Immunomodulation in Children With Crohn's DiseaseVitamin D Supplementation as Non-toxic Immunomodulation in Children With Crohn's DiseaseCrohn's Disease;Vitamin D DeficiencyDrug: CholecalciferolUniversity of California, Los AngelesThe Broad FoundationTerminated8 Years18 YearsAll3Phase 1United States
28NCT00742781
(ClinicalTrials.gov)
May 200926/8/2008Vitamin D Supplementation in Crohn's PatientsVitamin D and Crohn's Disease From the Bench to the ClinicInflammatory Bowel DiseaseDietary Supplement: Vitamin DPenn State UniversityNULLCompleted18 Years70 YearsAll21Phase 1United States
29NCT00672763
(ClinicalTrials.gov)
May 20082/5/2008Adjuvant Vitamin D With Corticosteroids in Active Crohn's DiseaseThe Immunomodulatory Role of Vitamin D in Inflammatory Bowel Disease (The IBDVit Study): Double-Blind, Placebo-Controlled Trial of Adjuvant Vitamin D (Colecalciferol) With Corticosteroids in Active Crohn's DiseaseCrohn's DiseaseDrug: Colecalciferol D3 (Vigantol Oil);Drug: Medium chain triglyceridesImperial College LondonNULLWithdrawn18 YearsN/ABoth0Phase 4United Kingdom
30EUCTR2008-001467-10-GB
(EUCTR)
30/04/200828/03/2008Trial of Adjuvant Vitamin D with Standard Maintenance Therapy in Preventing Relapse of Inflammatory Bowel Disease - IBDVit3 Ulcerative colitis - in remissionCrohn's Disease - in remission
MedDRA version: 9.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis
MedDRA version: 9.1;Classification code 10011401;Term: Crohn's disease
Trade Name: Vigantol Oel
Product Name: Vigantol Oel TM
Imperial College LondonNULLNot RecruitingFemale: yes
Male: yes
120United Kingdom
31EUCTR2008-001466-93-GB
(EUCTR)
30/04/200828/03/2008Trial of adjuvant vitamin D with Infliximab in active Crohn's Disease (IBDVit2). - IBDVit2 Active Crohn's Disease
MedDRA version: 9.1;Level: LLT;Classification code 10011401;Term: Crohn's disease
Trade Name: Vigantol Oel
Product Name: Vigantol Oel TM
Imperial College LondonNULLNot RecruitingFemale: yes
Male: yes
40United Kingdom
32EUCTR2007-006692-37-GB
(EUCTR)
10/04/200825/01/2008 The Immunomodulatory Role of Vitamin D in Inflammatory Bowel Disease (IBDVit): IBDVit1 - Trial of Adjuvant Vitamin D with Corticosteroids in Active Crohn’s Disease; IBDVit2 - Trial of Adjuvant Vitamin D with Infliximab in Active Crohn's Disease; IBDVit3 - Trial of Adjuvant Vitamin D with standard maintenance therapy in preventing relapse of Inflammatory Bowel Disease. - IBDVit The Immunomodulatory Role of Vitamin D in Inflammatory Bowel Disease (IBDVit): IBDVit1 - Trial of Adjuvant Vitamin D with Corticosteroids in Active Crohn’s Disease; IBDVit2 - Trial of Adjuvant Vitamin D with Infliximab in Active Crohn's Disease; IBDVit3 - Trial of Adjuvant Vitamin D with standard maintenance therapy in preventing relapse of Inflammatory Bowel Disease. - IBDVit IBDVit1 - Active Crohn's Disease IBDVit2 - Active Crohn's Disease IBDVit3 - Crohn's Disease in remission / Ulcerative Colitis in remission
MedDRA version: 9.1;Level: LLT;Classification code 10011401;Term: Crohn's disease
MedDRA version: 9.1;Classification code 10045365;Term: Ulcerative colitis
Trade Name: Vigantol Oel
Product Name: Vigantol Oel TM
Imperial College LondonNULLNot Recruiting Female: yes
Male: yes
210 Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): yesUnited Kingdom
33NCT00621257
(ClinicalTrials.gov)
January 200811/2/2008Vitamin D Levels in Children With IBDOptimization of Vitamin D Stores and Its Impact on the Bone Health and Disease Outcomes of Children and Adolescents With IBD.Inflammatory Bowel Disease;Crohn's Disease;Ulcerative ColitisDietary Supplement: ergocalciferol;Dietary Supplement: CholecalciferolBoston Children’s HospitalNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);Crohn's and Colitis Foundation;NASPGHAN FoundationTerminated5 Years21 YearsAll134N/AUnited States
34NCT00427804
(ClinicalTrials.gov)
January 200725/1/2007Tumor Necrosis Factor Decreases Vitamin D Dependant Calcium AbsorptionTumor Necrosis Factor-a Induces Vitamin D Resistance in Small Intestinal Calcium AbsorptionRheumatoid Arthritis;Crohn's DiseaseDrug: calcitriolAtlanta VA Medical CenterEmory UniversityCompleted18 Years50 YearsMale9N/AUnited States
35NCT00132184
(ClinicalTrials.gov)
September 200518/8/2005Vitamin D Treatment for Crohn´s DiseaseRemission Keeping and Remission Inducing Effect by Vitamin-D in Crohns Disease, and in Vitro Vitamin-D Mediated T-Cell ImmunomodulationCrohns DiseaseDrug: Vitamin DUniversity of AarhusNULLActive, not recruiting18 Years90 YearsBoth110Phase 2/Phase 3Denmark

97. 潰瘍性大腸炎


臨床試験数 : 2,630 薬物数 : 1,459 - (DrugBank : 265) / 標的遺伝子数 : 144 - 標的パスウェイ数 : 202
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04991324
(ClinicalTrials.gov)
September 21, 202227/7/2021Cholecalciferol Comedication in IBD - the 5C-studyCholecalciferol Comedication in Patients With Chronic Inflammatory Bowel Diseases (Crohn's Disease or Ulcerative Colitis) - the 5C-studyInflammatory Bowel DiseasesDrug: Vitamin D3University Hospital, Basel, SwitzerlandNULLRecruiting18 YearsN/AAll150Phase 3Switzerland
2NCT04828031
(ClinicalTrials.gov)
July 1, 202129/3/2021Vitamin D Regulation of Gut Specific B Cells and Antibodies Targeting Gut Bacteria in Inflammatory Bowel DiseaseVitamin D Regulation of a4ß7+ B Cell Immunophenotypes and Mucosal Antibody Response to Commensal Gut Bacteria in Patients With Inflammatory Bowel DiseaseCrohn Disease;Inflammatory Bowel Diseases;Ulcerative ColitisDrug: Vitamin DStanford UniversityDoris Duke Charitable FoundationRecruiting18 YearsN/AAll50Phase 1United States
3NCT04225819
(ClinicalTrials.gov)
October 1, 20203/1/2020Adjunctive Treatment With Vitamin D3 in Patients With Active IBDAdjunctive Treatment With Vitamin D3 in Patients With Active IBD (ACTIVATED): A Randomized, Double-blind, Placebo-controlled TrialIBD;Inflammatory Bowel Diseases;Crohn Disease;Ulcerative Colitis;Vitamin D3 DeficiencyDietary Supplement: Vitamin D3;Other: PlaceboMassachusetts General HospitalNULLRecruiting18 YearsN/AAll100N/AUnited States
4NCT04309058
(ClinicalTrials.gov)
March 202024/2/2020Observation of the Effect of Vitamin D Supplementation on Chronic Course of Patients With Ulcerative Colitis Based on Vitamin D Receptor Fok I Gene PolymorphismObservation of the Effect of Vitamin D Supplementation on Chronic Course of Patients With Ulcerative Colitis Based on Vitamin D Receptor Fok I Gene Polymorphism,a Prospective Cohort StudyUlcerative Colitis;Vitamin D Deficiency;Vitamin D SupplementDrug: Vitamin D dropsSecond Affiliated Hospital of Wenzhou Medical UniversityNULLNot yet recruitingN/AN/AAll100Early Phase 1China
5NCT03594708
(ClinicalTrials.gov)
April 30, 201819/1/2018Immunonutrition in Ulcerative ColitisImpact of Immunonutrition Supplementation Combining Fermentable Fiber, Omega-3 Fatty Acids, Vitamin D, Vitamin E, and Zinc on Intestinal Inflammation, Gut Microbial Activity, and Severity of Symptoms in Ulcerative Colitis PatientsUlcerative ColitisDietary Supplement: Nutrition supplement;Dietary Supplement: Placebo supplementBaptist Memorial Health Care CorporationNULLUnknown status18 YearsN/AAll30N/AUnited States
6NCT04276649
(ClinicalTrials.gov)
January 1, 201517/2/2020A Retrospective Analysis: the Influence of Caltrate Supplement on the Effect of Mesalazine in Ulcerative ColitisA Retrospective Analysis on the Influence of Caltrate Supplement on the Clinical Effect of Mesalazine in Ulcerative ColitisUlcerative Colitis;Vitamin D Deficiency;Vitamin D SupplementDrug: CaltrateSecond Affiliated Hospital of Wenzhou Medical UniversityNULLCompleted18 YearsN/AAll74China
7NCT01846026
(ClinicalTrials.gov)
April 201330/4/2013Ulcerative Colitis and Vitamin D SupplementationImmunomodulating and Clinical Effects of Vitamin D on Remission Induction in Patients With Moderate and Severe Ulcerative Colitis, Undergoing Treatment With Infliximab.Ulcerative ColitisDrug: Vitamin D;Drug: placeboUniversity Hospital of North NorwayNULLWithdrawn18 YearsN/ABoth0Phase 1/Phase 2Norway
8NCT01640496
(ClinicalTrials.gov)
July 201211/7/2012Vitamin D Treatment in Ulcerative ColitisVitamin D Treatment in Ulcerative ColitisUlcerative Colitis;Inflammatory Bowel DiseaseDrug: Vitamin D3;Other: PlaceboUniversity of ChicagoNorth Shore University HospitalWithdrawn18 YearsN/ABoth0N/AUnited States
9NCT01877577
(ClinicalTrials.gov)
April 201211/6/2013Supplementation of Vitamin D3 in Patients With Inflammatory Bowel Diseases and Hypovitaminosis DSupplementation of Vitamin D3 (Cholecalciferol) in Patients With Inflammatory Bowel Diseases (IBD) and Hypovitaminosis D: A Prospective Randomized Controlled Trial.Crohn's Disease (CD);Ulcerative Colitis (UC)Dietary Supplement: Vitamin D3University of California, San FranciscoNULLCompleted18 YearsN/ABoth30N/AUnited States
10EUCTR2009-015649-21-NO
(EUCTR)
21/10/200916/09/2009Immunmodulating and clinical effect of vitamin D onthe induction of remission in the patients with moderate to severe ulcerative colitis under the treatment with Infliximab.Immunmodulating and clinical effect of vitamin D onthe induction of remission in the patients with moderate to severe ulcerative colitis under the treatment with Infliximab. Ulcerative colitisTrade Name: Dekristol
Product Name: cholecalciferol
Product Code: na
Medical clinic, University Hospital of North NorwayNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
200Norway
11EUCTR2008-001467-10-GB
(EUCTR)
30/04/200828/03/2008Trial of Adjuvant Vitamin D with Standard Maintenance Therapy in Preventing Relapse of Inflammatory Bowel Disease - IBDVit3 Ulcerative colitis - in remissionCrohn's Disease - in remission
MedDRA version: 9.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis
MedDRA version: 9.1;Classification code 10011401;Term: Crohn's disease
Trade Name: Vigantol Oel
Product Name: Vigantol Oel TM
Imperial College LondonNULLNot RecruitingFemale: yes
Male: yes
120United Kingdom
12EUCTR2007-006692-37-GB
(EUCTR)
10/04/200825/01/2008 The Immunomodulatory Role of Vitamin D in Inflammatory Bowel Disease (IBDVit): IBDVit1 - Trial of Adjuvant Vitamin D with Corticosteroids in Active Crohn’s Disease; IBDVit2 - Trial of Adjuvant Vitamin D with Infliximab in Active Crohn's Disease; IBDVit3 - Trial of Adjuvant Vitamin D with standard maintenance therapy in preventing relapse of Inflammatory Bowel Disease. - IBDVit The Immunomodulatory Role of Vitamin D in Inflammatory Bowel Disease (IBDVit): IBDVit1 - Trial of Adjuvant Vitamin D with Corticosteroids in Active Crohn’s Disease; IBDVit2 - Trial of Adjuvant Vitamin D with Infliximab in Active Crohn's Disease; IBDVit3 - Trial of Adjuvant Vitamin D with standard maintenance therapy in preventing relapse of Inflammatory Bowel Disease. - IBDVit IBDVit1 - Active Crohn's Disease IBDVit2 - Active Crohn's Disease IBDVit3 - Crohn's Disease in remission / Ulcerative Colitis in remission
MedDRA version: 9.1;Level: LLT;Classification code 10011401;Term: Crohn's disease
MedDRA version: 9.1;Classification code 10045365;Term: Ulcerative colitis
Trade Name: Vigantol Oel
Product Name: Vigantol Oel TM
Imperial College LondonNULLNot Recruiting Female: yes
Male: yes
210 Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): yesUnited Kingdom
13NCT00621257
(ClinicalTrials.gov)
January 200811/2/2008Vitamin D Levels in Children With IBDOptimization of Vitamin D Stores and Its Impact on the Bone Health and Disease Outcomes of Children and Adolescents With IBD.Inflammatory Bowel Disease;Crohn's Disease;Ulcerative ColitisDietary Supplement: ergocalciferol;Dietary Supplement: CholecalciferolBoston Children’s HospitalNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);Crohn's and Colitis Foundation;NASPGHAN FoundationTerminated5 Years21 YearsAll134N/AUnited States

299. 嚢胞性線維症


臨床試験数 : 1,695 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT05276960
(ClinicalTrials.gov)
February 22, 202221/2/2022Efficacy of Intensive Cholecalciferol Monitoring and Supplementation on Serum vitD Levels in Pediatric Patients With CFA Randomized, Double-blind Study of the Efficacy of Intensive Cholecalciferol Monitoring and Supplementation on Serum Vitamin D Levels in Pediatric Patients With Cystic FibrosisVitamin D Deficiency;Cystic Fibrosis;Bone Density, Low;Inflammation Chronic;Cystic Fibrosis in Children;Cystic Fibrosis Pulmonary ExacerbationDrug: Cholecalciferol PillHospital Infantil de Mexico Federico GomezNULLRecruiting5 Years18 YearsAll40Phase 4Mexico
2NCT04118010
(ClinicalTrials.gov)
March 13, 20204/10/2019Vitamin D and Prebiotics for Intestinal Health in Cystic FibrosisVitamin D and Prebiotics for Intestinal Health in Cystic FibrosisCystic Fibrosis;DysbiosisDrug: Vitamin D3;Drug: Placebo vitamin D3;Drug: Inulin;Drug: Placebo InulinEmory UniversityNULLCompleted18 YearsN/AAll40Phase 4United States
3NCT03734744
(ClinicalTrials.gov)
June 17, 20196/11/2018PK/PD of Vitamin D3 in Adults With CFA Pilot Study Evaluating Single, High-dose Pharmacokinetics/Pharmacodynamics of Vitamin D3 in CFVitamin D Deficiency;Cystic FibrosisDietary Supplement: Vitamin D3University of Southern CaliforniaNULLTerminated18 YearsN/AAll6N/AUnited States
4NCT04411901
(ClinicalTrials.gov)
March 1, 201822/5/2020The Role of Vitamin D3 in Pediatric Bronchiectasis SeverityThe Role of Vitamin D3 in Pediatric Bronchiectasis Severity( CF Versus Non CF Bronchioectasis)Cystic Fibrosis and Non CF BronchiectasisDrug: Cholecalciferol (vitaminD3)Heba OmaraNULLCompleted1 Year17 YearsAll40Phase 2/Phase 3Egypt
5NCT02613884
(ClinicalTrials.gov)
November 201620/11/2015Safety, Efficacy, and Feasibility of High-dose Cholecalciferol in Pediatric Patients With Cystic FibrosisSafety, Efficacy, and Feasibility of High-dose Cholecalciferol in Pediatric Patients With Cystic FibrosisVitamin D DeficiencyDrug: TreatmentJohns Hopkins All Children's HospitalNULLCompleted36 Months18 YearsAll30Phase 2United States
6NCT02589444
(ClinicalTrials.gov)
December 201520/10/2015Vitamin D and Microbiota in Cystic FibrosisPilot Study Evaluating the Role of Vitamin D Repletion on Gut and Lung Microbiota in Cystic FibrosisVitamin D Deficiency;Cystic FibrosisDietary Supplement: High-Dose Vitamin D3;Other: Stool Sample;Other: Sputum Sample;Other: Sham Comparator;Procedure: Blood drawEmory UniversityNULLCompleted18 YearsN/AAll41N/AUnited States
7NCT02507843
(ClinicalTrials.gov)
January 201522/7/2015Vitamin D as an Adjunctive Treatment in Patients With Non-Cystic Fibrosis BronchiectasisVitamin D as an Adjunctive Treatment in Patients With Non-Cystic Fibrosis Bronchiectasis: a Double-blind Randomised Controlled TrialBronchiectasisDrug: Cholecalciferol;Drug: PlaceboShanghai Pulmonary Hospital, Shanghai, ChinaNULLRecruiting18 YearsN/ABoth200Phase 4China
8NCT02043717
(ClinicalTrials.gov)
January 201412/1/2014Increased Vitamin D Reduces Pulmonary Exacerbations in CFIncreasing Vitamin D Serum Levels Reduces Pulmonary Exacerbations in Patients With Cystic FibrosisCystic FibrosisDietary Supplement: Vitamin DHadassah Medical OrganizationNULLCompleted4 YearsN/AAll90N/AIsrael
9NCT01880346
(ClinicalTrials.gov)
October 201312/6/2013Comparison of Absorption of Vitamin D in Cystic FibrosisVehicles for the Absorption of Vitamin D in Cystic Fibrosis: Comparison of Powder vs OilCystic FibrosisDietary Supplement: Vitamin D Powder;Dietary Supplement: Vitamin D OilEmory UniversityNULLCompleted18 Years59 YearsBoth17Phase 4United States
10NCT01426256
(ClinicalTrials.gov)
October 201129/8/2011Vitamin D for Enhancing the Immune System in Cystic Fibrosis (DISC Study)Vitamin D for Enhancing the Immune System in Cystic FibrosisCystic Fibrosis;Respiratory Tract InfectionsDietary Supplement: CholecalciferolEmory UniversityCystic Fibrosis Foundation TherapeuticsCompleted16 YearsN/AAll91Phase 3United States
11NCT01222273
(ClinicalTrials.gov)
September 201014/10/2010Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary AspergillosisOpen-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary AspergillosisCystic Fibrosis;Allergic Bronchopulmonary AspergillosisDietary Supplement: cholecalciferol (Vitamin D3)University of PittsburghNational Heart, Lung, and Blood Institute (NHLBI)Completed12 YearsN/AAll7N/AUnited States
12NCT01321905
(ClinicalTrials.gov)
April 201023/3/2011Prospective Intervention Study on Vitamin D in Patients With Cystic Fibrosis5-month Pilot Intervention Study on Vitamin D in Patients With Cystic FibrosisCystic FibrosisDietary Supplement: Supplementation with vitamin D2/D3Karolinska InstitutetStockholm County Council, Sweden;Swedish Cystic Fibrosis AssociationRecruiting6 YearsN/ABoth15Phase 2Sweden
13NCT00685971
(ClinicalTrials.gov)
December 200827/5/2008Cholecalciferol for Vitamin D in Adult Cystic Fibrosis (CF) PatientsRandomized Placebo-Controlled Trial of Cholecalciferol for Vitamin D Deficiency in Adults With Cystic FibrosisCystic Fibrosis;Vitamin D DeficiencyDietary Supplement: 5000 IU of cholecalciferol;Dietary Supplement: placeboSt. Michael's Hospital, TorontoNULLCompleted18 YearsN/ABoth200N/ACanada
14NCT00788138
(ClinicalTrials.gov)
October 20087/11/2008Effects of Vitamin D Supplementation on Lung Function in an Acute Pulmonary Exacerbation of Cystic FibrosisCystic FibrosisDietary Supplement: Vitamin D3;Dietary Supplement: PlaceboEmory UniversityNULLCompleted18 Years70 YearsBoth30N/AUnited States
15NCT00762918
(ClinicalTrials.gov)
March 200826/9/2008Vitamin D3 for the Treatment of Low Vitamin D in Cystic FibrosisVitamin D and Its Non-Classic Roles in Cystic FibrosisCystic Fibrosis;Vitamin D DeficiencyDietary Supplement: cholecalciferolChildren's Hospital of PhiladelphiaNULLWithdrawn10 Years25 YearsBoth0Phase 3United States
16NCT00450073
(ClinicalTrials.gov)
November 200619/3/2007Improving Vitamin D Status In Cystic FibrosisDesktop Tanning Unit to Improve Vitamin D Status in Patients With Cystic Fibrosis and Short Bowel Syndrome: A Pilot StudyCystic FibrosisDrug: ergocalciferol (vitamin D2);Device: Sperti Del Sol Lamp;Drug: Vitamin D3Atlanta VA Medical CenterEmory UniversityCompleted18 Years60 YearsAll30N/AUnited States