OsrhAAT 20 mg/kg IV ( DrugBank: - )

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1 disease

ID	Disease name (Link within this page)	Number of trials
231	Alpha-1-antitrypsin deficiency	1

231. Alpha-1-antitrypsin deficiency

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Clinical trials : 93 /  Drugs : 77 - (DrugBank : 8) / Drug target genes : 10 - Drug target pathways : 36

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05315921 (ClinicalTrials.gov)	March 22, 2022	30/3/2022	Study of OsrhAAT or Placebo in Healthy Volunteers	A Phase 1, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of Single Ascending Doses of OsrhAAT in Healthy Volunteers	Emphysema Secondary to Congenital AATD	Drug: OsrhAAT 1 mg/kg IV;Drug: OsrhAAT 3 mg/kg IV;Drug: OsrhAAT 10 mg/kg IV;Drug: OsrhAAT 20 mg/kg IV;Drug: OsrhAAT 40 mg/kg IV;Drug: OsrhAAT 60 mg/kg IV	Healthgen Biotechnology Corp.	NULL	Recruiting	18 Years	55 Years	All	48	Phase 1	United States