Povetacicept ( DrugBank: - )


3 diseases
IDDisease name (Link within this page)Number of trials
61Autoimmune hemolytic anemia1
63Idiopathic thrombocytopenic purpura1
222Primary nephrotic syndrome1

61. Autoimmune hemolytic anemia


Clinical trials : 146 Drugs : 131 - (DrugBank : 59) / Drug target genes : 28 - Drug target pathways : 158
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
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size
PhaseCountries
1NCT05757570
(ClinicalTrials.gov)
May 202324/2/2023An Open-label Study of Povetacicept in Subjects With Autoimmune CytopeniasA Phase 1b Open-Label Study to Assess the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Povetacicept in Subjects With Autoimmune Cytopenias (RUBY-4)Immune Thrombocytopenia;Idiopathic Thrombocytopenic Purpura;Warm Autoimmune Hemolytic Anemia;Cold Agglutinin DiseaseDrug: povetaciceptAlpine Immune Sciences, Inc.NULLNot yet recruiting18 YearsN/AAll42Phase 1NULL

63. Idiopathic thrombocytopenic purpura


Clinical trials : 391 Drugs : 235 - (DrugBank : 50) / Drug target genes : 49 - Drug target pathways : 139
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT05757570
(ClinicalTrials.gov)
May 202324/2/2023An Open-label Study of Povetacicept in Subjects With Autoimmune CytopeniasA Phase 1b Open-Label Study to Assess the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Povetacicept in Subjects With Autoimmune Cytopenias (RUBY-4)Immune Thrombocytopenia;Idiopathic Thrombocytopenic Purpura;Warm Autoimmune Hemolytic Anemia;Cold Agglutinin DiseaseDrug: povetaciceptAlpine Immune Sciences, Inc.NULLNot yet recruiting18 YearsN/AAll42Phase 1NULL

222. Primary nephrotic syndrome


Clinical trials : 310 Drugs : 295 - (DrugBank : 117) / Drug target genes : 63 - Drug target pathways : 194
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT05732402
(ClinicalTrials.gov)
March 20238/2/2023An Open-label Study of Povetacicept (ALPN-303) in Autoimmune Kidney DiseasesAn Open-Label, Multiple-Ascending Dose Study to Assess the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Different Dose Levels of Povetacicept in Subjects With Autoantibody-Associated Glomerular Diseases (RUBY-3)Lupus Nephritis;Immunoglobulin A Nephropathy;Membranous NephropathyDrug: povetaciceptAlpine Immune Sciences, Inc.NULLNot yet recruiting18 YearsN/AAll42Phase 1NULL