Drug（薬物リスト） DrugBank | All Description Patterns💬 Info on mouse-over

No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	指定難病告示番号
1	Aliskiren	Aliskiren	1件: D03208 💬	1件: REN 💬	3件: Diabetic cardiomyopathy, Renin secretion, Renin-angiotensin system	4件: 66, 167, 222, 223 💬
2	Aprovel	-	-	-	-	1件: 167 💬
3	Atenolol	Atenolol	1件: D00235 💬	1件: ADRB1 💬	10件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 167 💬
4	Atenolol or propranolol	Atenolol	3件: D00235, D00483, D08443 💬	3件: ADRB1, ADRB2, ADRB3 💬	11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 167 💬
5	Blokium 50	-	-	-	-	1件: 167 💬
6	Blokium 50 mg comprimidos	-	-	-	-	1件: 167 💬
7	Coozar	-	-	-	-	1件: 167 💬
8	Coversyl	-	-	-	-	2件: 19, 167 💬
9	Coversyl (perindopril)	Perindopril	2件: D00624, D03753 💬	1件: ACE 💬	6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system	1件: 167 💬
10	Cozaar	-	-	-	-	1件: 167 💬
11	Cozaar 50	-	-	-	-	1件: 167 💬
12	Cozaar inicio 12,5 mg comprimidos recubiertos con pelicula	-	-	-	-	1件: 167 💬
13	Doxycycline	Doxycycline	5件: D00307, D02129, D03903, D03904, D07876 💬	-	-	15件: 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 162, 167, 227, 280, 299 💬
14	Doxycycline 100-200mg capsules daily for 6 months	Doxycycline	5件: D00307, D02129, D03903, D03904, D07876 💬	-	-	1件: 167 💬
15	Doxycycline hyclate ph.eur	Doxycycline	5件: D00307, D02129, D03903, D03904, D07876 💬	-	-	1件: 167 💬
16	Irbesartan	Irbesartan	1件: D00523 💬	1件: AGTR1 💬	16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway	4件: 66, 167, 168, 222 💬
17	Irbesartan 150-300mg capsules daily for 6 months	Irbesartan	1件: D00523 💬	1件: AGTR1 💬	16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway	1件: 167 💬
18	Lobivon	-	-	-	-	1件: 167 💬
19	Lobivon*28cpr 5mg	-	-	-	-	1件: 167 💬
20	Lortaan	-	-	-	-	1件: 167 💬
21	Lortaan*28cpr riv div 50mg	-	-	-	-	1件: 167 💬
22	Losartan	Losartan	2件: D00357, D08146 💬	1件: AGTR1 💬	16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
23	Losartan and atenolol or propranolol	Atenolol	5件: D00235, D00357, D00483, D08146, D08443 💬	4件: ADRB1, ADRB2, ADRB3, AGTR1 💬	22件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Renin-angiotensin system, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 167 💬
24	Losartan and nebivolol	Losartan	3件: D00357, D05127, D08146 💬	2件: ADRB1, AGTR1 💬	21件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Renin-angiotensin system, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 167 💬
25	Losartan potassium	Losartan	3件: D00357, D08146, D08403 💬	1件: AGTR1 💬	16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway	5件: 36, 98, 167, 179, 215 💬
26	Nebivolol	Nebivolol	1件: D05127 💬	1件: ADRB1 💬	10件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway	3件: 17, 113, 167 💬
27	Perindopril	Perindopril	2件: D00624, D03753 💬	1件: ACE 💬	6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system	3件: 113, 167, 222 💬
28	Potassium	Potassium	1件: D08403 💬	-	-	10件: 36, 46, 66, 67, 98, 115, 167, 179, 215, 235 💬
29	Propranolol	Propranolol	2件: D00483, D08443 💬	3件: ADRB1, ADRB2, ADRB3 💬	11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway	5件:  6 , 158, 167, 227, 278 💬
30	Verapamil	Verapamil	2件: D00619, D02356 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	36件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	3件: 96, 140, 167 💬
31	Verapamil sr	Verapamil	2件: D00619, D02356 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	36件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 167 💬
32	Vibrox	-	-	-	-	1件: 167 💬
33	Vibrox 100mg capsules	-	-	-	-	1件: 167 💬

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