Drug（薬物リスト） DrugBank | All Description Patterns💬 Info on mouse-over

No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	指定難病告示番号
1	Act-064992 (macitentan)	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 85 💬
2	Era and pde-5i (sildenafil, tadalafil, bosentan, macitentan)	Bosentan	6件: D01227, D02008, D02229, D07538, D08514, D10135 💬	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
3	Fdc macitentan/tadalafil	Macitentan	2件: D02008, D10135 💬	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
4	Macitentan	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	5件: 51, 85, 86, 88, 210 💬
5	Macitentan (act-064992)	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
6	Macitentan 10 mg	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	3件: 51, 86, 88 💬
7	Macitentan 10 mg tablet, once daily.	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
8	Macitentan 10mg	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 51 💬
9	Macitentan 3 mg	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 51 💬
10	Macitentan 37.5 mg	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
11	Macitentan 3mg	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 51 💬
12	Macitentan 75 mg	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
13	Macitentan group	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
14	Macitentan tablets	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	2件: 86, 88 💬
15	Observational study with patients treated with tracleer, ventavis, veletri, opsumit and/or uptravi	-	-	-	-	1件: 86 💬
16	Opsumit	-	-	-	-	3件: 86, 88, 210 💬
17	Opsumit (macitentan)	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
18	Opsumit 10 mg tablet	-	-	-	-	1件: 51 💬
19	Opsumit®	-	-	-	-	3件: 86, 88, 210 💬