Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
| 1 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B 1件: PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 1件: 294 💬 |
| 2 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B 1件: PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 1件: 294 💬 |
| 3 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
PDE3A 2件: PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 1件: 294 💬 |
| 4 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
PDE3A 2件: PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 1件: 294 💬 |
| 5 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE3A 2件: PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 1件: 294 💬 |
| 6 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE3A 2件: PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 1件: 294 💬 |
| 7 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE5A 1件: PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
| 8 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
| 9 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 10 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 11 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 12 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 13 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 14 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 15 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 16 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 17 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PDE3B 1件: PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 1件: 294 💬 |
| 18 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PDE3B 1件: PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 1件: 294 💬 |
| 19 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PDE3B 1件: PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 1件: 294 💬 |
| 20 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PDE3B 1件: PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 1件: 294 💬 |
| 21 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 22 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 23 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 24 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 25 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE3A 2件: PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 1件: 294 💬 |
| 26 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE3A 2件: PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 1件: 294 💬 |
| 27 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE5A 1件: PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
| 28 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
| 29 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
PDE3A 2件: PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 1件: 294 💬 |
| 30 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
PDE3A 2件: PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 1件: 294 💬 |
| 31 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 32 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 33 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 34 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 16件: 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 35 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PDE3B 1件: PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 1件: 294 💬 |
| 36 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PDE3B 1件: PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 1件: 294 💬 |
| 37 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE3A 2件: PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 1件: 294 💬 |
| 38 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE3A 2件: PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 1件: 294 💬 |
| 39 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE5A 1件: PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
| 40 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
| 41 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
PDE3B 1件: PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 1件: 294 💬 |
| 42 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
PDE3B 1件: PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 1件: 294 💬 |
| 43 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PDE3A 2件: PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 1件: 294 💬 |
| 44 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PDE3A 2件: PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 1件: 294 💬 |