DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adipocytokine signaling pathway 💬	1件: JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
2	Adipocytokine signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
3	Adipocytokine signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
4	African trypanosomiasis 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
5	African trypanosomiasis 💬	1件: IL1B 💬	D09911 💬	Gevokizumab	4件: 41, 50, 56, 269 💬
6	African trypanosomiasis 💬	1件: IL6 💬	D10080 💬	Sirukumab	2件: 41, 46 💬
7	African trypanosomiasis 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
8	African trypanosomiasis 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
9	AGE-RAGE signaling pathway in diabetic complications 💬	1件: IL1B 💬	D09911 💬	Gevokizumab	4件: 41, 50, 56, 269 💬
10	AGE-RAGE signaling pathway in diabetic complications 💬	1件: IL6 💬	D10080 💬	Sirukumab	2件: 41, 46 💬

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