DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adipocytokine signaling pathway 💬	1件: JAK2 💬	D10308 💬	Baricitinib	9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
2	Adipocytokine signaling pathway 💬	1件: JAK2 💬	D09970 💬	Tofacitinib	12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
3	Adipocytokine signaling pathway 💬	1件: TNF 💬	D00742 💬	Etanercept	15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
4	Adipocytokine signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
5	Adipocytokine signaling pathway 💬	1件: TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
6	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00437 💬	Nifedipine	2件: 50, 81 💬
7	African trypanosomiasis 💬	4件: IL10, IL1B, IL6, TNF 💬	D01583 💬	Pirfenidone	10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
8	African trypanosomiasis 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
9	African trypanosomiasis 💬	1件: IL1B 💬	D09911 💬	Gevokizumab	4件: 41, 50, 56, 269 💬
10	African trypanosomiasis 💬	1件: TNF 💬	D00742 💬	Etanercept	15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬

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