DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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19 / 286 pathways

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adipocytokine signaling pathway 💬	2件: PRKAA1, PRKAA2 💬	D00944 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
2	Adipocytokine signaling pathway 💬	2件: PRKAA1, PRKAA2 💬	D04966 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
3	AMPK signaling pathway 💬	2件: PRKAA1, PRKAA2 💬	D00944 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
4	AMPK signaling pathway 💬	2件: PRKAA1, PRKAA2 💬	D04966 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
5	Apelin signaling pathway 💬	2件: PRKAA1, PRKAA2 💬	D00944 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
6	Apelin signaling pathway 💬	2件: PRKAA1, PRKAA2 💬	D04966 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
7	Autophagy - animal 💬	2件: PRKAA1, PRKAA2 💬	D00944 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
8	Autophagy - animal 💬	2件: PRKAA1, PRKAA2 💬	D04966 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
9	Circadian rhythm 💬	2件: PRKAA1, PRKAA2 💬	D00944 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
10	Circadian rhythm 💬	2件: PRKAA1, PRKAA2 💬	D04966 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬

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