Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Ataluren	Ataluren	[1] D09323 💬	-	-	[6] 19, 113, 140, 246, 299, 329 💬
2	Cannabidiol	Cannabidiol	[1] D10915 💬	[2] CNR1, CNR2 💬	[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis	[17]  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 226, 271 💬
3	Cannabidiol (cbd)	Cannabidiol	[1] D10915 💬	[2] CNR1, CNR2 💬	[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis	[6]  6 , 140, 144, 145, 156, 158 💬
4	Cannabidiol oral solution	Cannabidiol	[1] D10915 💬	[2] CNR1, CNR2 💬	[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis	[4] 140, 144, 145, 193 💬
5	Carbidopa	Carbidopa	[1] D00558 💬	[1] DDC 💬	[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism	[9]  2 ,  4 ,  6 , 13, 17, 90, 140, 164, 201 💬
6	Cbd	-	-	-	-	[11]  2 ,  6 ,  8 , 13, 46, 140, 144, 145, 156, 158, 206 💬
7	Cbd - oral solution, is known as epidiolex, and is the approved name in the usa.	-	-	-	-	[3] 140, 144, 158 💬
8	Clemizole	Clemizole	-	-	-	[1] 140 💬
9	Clobazam	Clobazam	[1] D01253 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	[2] 140, 144 💬
10	Diacomit	-	-	-	-	[1] 140 💬
11	Diacomit (stiripentol)	Stiripentol	[1] D05928 💬	-	-	[1] 140 💬
12	Epx-100 (clemizole hcl)	Clemizole	-	-	-	[1] 140 💬
13	Epx-100 (clemizole hydrochloride)	Clemizole	-	-	-	[1] 140 💬
14	Fenfluramina	Fenfluramine	[1] D07945 💬	[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬	[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	[1] 140 💬
15	Fenfluramina cloridrato	Fenfluramine	[1] D07945 💬	[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬	[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	[1] 140 💬
16	Fenfluramine	Fenfluramine	[1] D07945 💬	[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬	[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	[3] 140, 144, 145 💬
17	Fenfluramine hydrochloride	Fenfluramine	[1] D07945 💬	[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬	[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	[2] 140, 144 💬
18	Fenfluramine hydrochloride (colorless)	Fenfluramine	[1] D07945 💬	[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬	[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	[2] 140, 144 💬
19	Fenfluramine hydrochloride (red)	Fenfluramine	[1] D07945 💬	[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬	[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	[1] 140 💬
20	Frisium	-	-	-	-	[1] 140 💬
21	Frisium*30cps 10mg	-	-	-	-	[1] 140 💬
22	Gwp42003-p	-	-	-	-	[5] 140, 144, 145, 156, 158 💬
23	Gwp42003-p 10 mg/kg/day dose	-	-	-	-	[1] 140 💬
24	Gwp42003-p 20 mg/kg/day dose	-	-	-	-	[2] 140, 144 💬
25	Gwp42003-p 5 mg/kg/day dose	-	-	-	-	[1] 140 💬
26	Levodopa	Levodopa	[1] D00059 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[8]  2 ,  4 ,  6 , 17, 90, 140, 164, 201 💬
27	Lorcaserin	Lorcaserin	[1] D06613 💬	-	-	[1] 140 💬
28	Me2080 (stiripentol)	Stiripentol	[1] D05928 💬	-	-	[1] 140 💬
29	None	-	-	-	-	[14] 46, 65, 78, 84, 85, 96, 97, 140, 160, 161, 171, 231, 271, 299 💬
30	None at this time	-	-	-	-	[2] 96, 140 💬
31	Other antiepileptics	-	-	-	-	[1] 140 💬
32	Placebo	-	-	-	-	[26]  3 ,  5 ,  6 , 13, 14, 37, 40, 46, 49, 50, 51, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276 💬
33	Procedure: 12-lead ecg	-	-	-	-	[2] 140, 144 💬
34	Stiripentol	Stiripentol	[1] D05928 💬	-	-	[1] 140 💬
35	Stiripentolo	-	-	-	-	[1] 140 💬
36	Stk-001	-	-	-	-	[1] 140 💬
37	Tak-935	-	-	-	-	[2] 140, 144 💬
38	Topamax	-	-	-	-	[1] 140 💬
39	Topiramate	Topiramate	[1] D00537 💬	[36] CA2, CA4, CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[52] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[5]  6 , 140, 144, 156, 193 💬
40	Turmeric	Turmeric	-	-	-	[4] 140, 144, 158, 299 💬
41	Verapamil	Verapamil	[2] D00619, D02356 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	[36] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[3] 96, 140, 167 💬
42	Zx008	-	-	-	-	[2] 140, 144 💬
43	Zx008 (fenfluramine hydrochloride)	Fenfluramine	[1] D07945 💬	[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬	[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	[2] 140, 144 💬
44	Zx008 - 0.2 mg/kg/day	-	-	-	-	[1] 140 💬
45	Zx008 - 0.4 mg/kg/day	-	-	-	-	[1] 140 💬
46	Zx008 - 0.8 mg/kg/day	-	-	-	-	[1] 140 💬
47	Zx008 - 20 mg/day maximum dose	-	-	-	-	[1] 140 💬
48	Zx008 0.2 and 0.8 mg/kg/day	-	-	-	-	[2] 140, 144 💬

Back to top