Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Any other approved antiepileptic drug	-	-	-	-	[1] 144 💬
2	Cannabidiol	Cannabidiol	[1] D10915 💬	[2] CNR1, CNR2 💬	[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis	[17]  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 226, 271 💬
3	Cannabidiol (cbd)	Cannabidiol	[1] D10915 💬	[2] CNR1, CNR2 💬	[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis	[6]  6 , 140, 144, 145, 156, 158 💬
4	Cannabidiol oral solution	Cannabidiol	[1] D10915 💬	[2] CNR1, CNR2 💬	[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis	[4] 140, 144, 145, 193 💬
5	Carisbamate	Carisbamate	[1] D06573 💬	-	-	[1] 144 💬
6	Cbd	-	-	-	-	[11]  2 ,  6 ,  8 , 13, 46, 140, 144, 145, 156, 158, 206 💬
7	Cbd - oral solution, is known as epidiolex, and is the approved name in the usa.	-	-	-	-	[3] 140, 144, 158 💬
8	Clobazam	Clobazam	[1] D01253 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	[2] 140, 144 💬
9	Clobazam high dose	Clobazam	[1] D01253 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	[1] 144 💬
10	Clobazam low dose	Clobazam	[1] D01253 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	[1] 144 💬
11	Clobazam medium dose	Clobazam	[1] D01253 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	[1] 144 💬
12	Clobazam pheur	Clobazam	[1] D01253 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	[1] 144 💬
13	Clobazam tablets	Clobazam	[1] D01253 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	[1] 144 💬
14	Clobazam tablets 10mg	Clobazam	[1] D01253 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	[1] 144 💬
15	Clobazam tablets 20mg	Clobazam	[1] D01253 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	[1] 144 💬
16	Clobazam tablets 5mg	Clobazam	[1] D01253 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	[1] 144 💬
17	E2007	-	-	-	-	[2]  6 , 144 💬
18	E2080	-	-	-	-	[1] 144 💬
19	Ezogabine	Ezogabine	[1] D09569 💬	[5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬	[6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection	[2]  2 , 144 💬
20	Ezogabine (us only)	Ezogabine	[1] D09569 💬	[5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬	[6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection	[1] 144 💬
21	Ezogabine/retigabine	Ezogabine	[1] D09569 💬	[5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬	[6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection	[1] 144 💬
22	Fenfluramine	Fenfluramine	[1] D07945 💬	[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬	[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	[3] 140, 144, 145 💬
23	Fenfluramine hcl, dl-fenfluramine, (±)-fenfluramine	Fenfluramine	[1] D07945 💬	[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬	[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	[1] 144 💬
24	Fenfluramine hydrochloride	Fenfluramine	[1] D07945 💬	[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬	[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	[2] 140, 144 💬
25	Fenfluramine hydrochloride (colorless)	Fenfluramine	[1] D07945 💬	[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬	[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	[2] 140, 144 💬
26	Fycompa	-	-	-	-	[2]  2 , 144 💬
27	Gw582892	-	-	-	-	[1] 144 💬
28	Gwp42003-p	-	-	-	-	[5] 140, 144, 145, 156, 158 💬
29	Gwp42003-p 20 mg/kg/day dose	-	-	-	-	[2] 140, 144 💬
30	Inovelon	-	-	-	-	[1] 144 💬
31	Investigators choice of approved aed	-	-	-	-	[1] 144 💬
32	Investigators choice of approved aeds	-	-	-	-	[1] 144 💬
33	Lamictal	-	-	-	-	[1] 144 💬
34	Lamotrigine	Lamotrigine	[1] D00354 💬	[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	[5] 13, 34, 38, 114, 144 💬
35	Melatonin	Melatonin	[1] D08170 💬	[2] MTNR1A, MTNR1B 💬	[2] Circadian entrainment, Neuroactive ligand-receptor interaction	[11]  6 ,  8 , 13, 46, 49, 90, 97, 144, 145, 149, 202 💬
36	Perampanel	Perampanel	[1] D08964 💬	[4] GRIA1, GRIA2, GRIA3, GRIA4 💬	[16] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway	[3]  2 ,  6 , 144 💬
37	Placebo	-	-	-	-	[26]  3 ,  5 ,  6 , 13, 14, 37, 40, 46, 49, 50, 51, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276 💬
38	Potiga	-	-	-	-	[1] 144 💬
39	Procedure: 12-lead ecg	-	-	-	-	[2] 140, 144 💬
40	Retigabine	Ezogabine	[1] D09569 💬	[5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬	[6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection	[2]  2 , 144 💬
41	Retigabine/ezogabine	Ezogabine	[1] D09569 💬	[5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬	[6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection	[1] 144 💬
42	Rufinamide	Rufinamide	[1] D05775 💬	[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	[1] 144 💬
43	Rufinamide (e2080)	Rufinamide	[1] D05775 💬	[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	[1] 144 💬
44	Rufinamide oral suspension	Rufinamide	[1] D05775 💬	[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	[1] 144 💬
45	Sodio valproato	-	-	-	-	[1] 144 💬
46	Tak-935	-	-	-	-	[2] 140, 144 💬
47	Topimarate	-	-	-	-	[1] 144 💬
48	Topimarato	-	-	-	-	[1] 144 💬
49	Topiramate	Topiramate	[1] D00537 💬	[36] CA2, CA4, CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[52] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[5]  6 , 140, 144, 156, 193 💬
50	Turmeric	Turmeric	-	-	-	[4] 140, 144, 158, 299 💬
51	Zx008	-	-	-	-	[2] 140, 144 💬
52	Zx008 (fenfluramine hydrochloride)	Fenfluramine	[1] D07945 💬	[4] HTR2A, HTR2B, HTR2C, SLC6A4 💬	[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	[2] 140, 144 💬
53	Zx008 0.2 and 0.8 mg/kg/day	-	-	-	-	[2] 140, 144 💬
54	Zx008 0.2 or 0.8 mg/kg/day	-	-	-	-	[1] 144 💬

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