Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Abc008	-	-	-	-	[1] 15 💬
2	Alemtuzumab	Alemtuzumab	[1] D02802 💬	-	-	[16] 13, 15, 19, 20, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284 💬
3	Alemtuzumab (campath)	Alemtuzumab	[1] D02802 💬	-	-	[1] 15 💬
4	Anakinra	Anakinra	[1] D02934 💬	[2] IL1R1, IL1R2 💬	[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer	[17]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 84, 86, 97, 106, 107, 299 💬
5	Arimoclomol	Arimoclomol	[1] D11374 💬	-	-	[3]  2 , 15, 19 💬
6	Arimoclomol citrate	Arimoclomol	[1] D11374 💬	-	-	[2] 15, 19 💬
7	Bimagrumab	Bimagrumab	[1] D10620 💬	[2] ACVR2A, ACVR2B 💬	[4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway	[1] 15 💬
8	Botulinum toxin type a	Botulinum toxin type A	[1] D00783 💬	[1] SNAP25 💬	[2] Insulin secretion, Synaptic vesicle cycle	[10]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 70, 113, 149 💬
9	Brx-345	-	-	-	-	[2]  2 , 15 💬
10	Bym338	-	-	-	-	[1] 15 💬
11	Bym338 (bimagrumab)	Bimagrumab	[1] D10620 💬	[2] ACVR2A, ACVR2B 💬	[4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway	[1] 15 💬
12	Bym338/bimagrumab	Bimagrumab	[1] D10620 💬	[2] ACVR2A, ACVR2B 💬	[4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway	[1] 15 💬
13	Care as usual	-	-	-	-	[1] 15 💬
14	Etanercept	Etanercept	[1] D00742 💬	[2] LTA, TNF 💬	[65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	[14] 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
15	Flebogamma 5%	-	-	-	-	[1] 15 💬
16	Gamma globulin	-	-	-	-	[2] 15, 50 💬
17	Immunoglobulins, normal human, for intravascular adm.	-	-	-	-	[2] 14, 15 💬
18	Natalizumab	Natalizumab	[1] D06886 💬	[1] ITGA4 💬	[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection	[4] 13, 15, 46, 96 💬
19	Null	-	-	-	-	[16]  6 , 13, 15, 28, 37, 46, 49, 51, 63, 86, 90, 96, 97, 107, 145, 271 💬
20	Other: blood-flow restricted training	-	-	-	-	[1] 15 💬
21	Phenylbutyrate	Phenylbutyric acid	[1] D05868 💬	-	-	[11]  2 ,  3 ,  6 ,  8 , 15, 93, 94, 244, 251, 297, 299 💬
22	Phenylbutyrate oral tablet	Phenylbutyric acid	[1] D05868 💬	-	-	[1] 15 💬
23	Pioglitazone	Pioglitazone	[2] D00945, D08378 💬	[1] PPARG 💬	[9] AMPK signaling pathway, Huntington disease, Longevity regulating pathway, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer	[17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
24	Raav1.cmv.hufollistatin344	-	-	-	-	[2] 15, 113 💬
25	Rapamycin	Sirolimus	[1] D00753 💬	[1] MTOR 💬	[50] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway	[18]  2 , 15, 34, 35, 46, 49, 51, 60, 61, 67, 86, 89, 96, 157, 158, 256, 278, 279 💬
26	Regn2477+regn1033	-	-	-	-	[1] 15 💬
27	Simvastatin	Simvastatin	[1] D00434 💬	[1] HMGCR 💬	[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis	[21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
28	Sivastin	-	-	-	-	[1] 15 💬
29	Xeomin	-	-	-	-	[7]  5 ,  6 ,  7 , 13, 15, 17, 113 💬

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