Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Acetate	Acetate	-	-	-	[43]  1 ,  2 ,  6 , 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299 💬
2	Administration of a high dose of desipramine	Desipramine	[2] D00812, D07791 💬	[2] SLC6A2, SLC6A4 💬	[2] Serotonergic synapse, Synaptic vesicle cycle	[1] 156 💬
3	Administration of a low dose of desipramine	Desipramine	[2] D00812, D07791 💬	[2] SLC6A2, SLC6A4 💬	[2] Serotonergic synapse, Synaptic vesicle cycle	[1] 156 💬
4	Alpha-tocotrienol quinone	Tocotrienol	-	-	-	[1] 156 💬
5	Ana001xhcl (syntagon) or vexa-04 (patheon)	-	-	-	-	[1] 156 💬
6	Anavex2-73	-	-	-	-	[2]  6 , 156 💬
7	Anavex2-73 (blarcamesine)	Blarcamesine	[1] D11383 💬	[6] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, SIGMAR1 💬	[14] Alzheimer disease, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway	[1] 156 💬
8	Anavex2-73 oral liquid	-	-	-	-	[1] 156 💬
9	Blarcamesine	Blarcamesine	[1] D11383 💬	[6] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, SIGMAR1 💬	[14] Alzheimer disease, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway	[1] 156 💬
10	Cannabidiol	Cannabidiol	[1] D10915 💬	[2] CNR1, CNR2 💬	[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis	[17]  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 226, 271 💬
11	Cannabidiol (cbd)	Cannabidiol	[1] D10915 💬	[2] CNR1, CNR2 💬	[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis	[6]  6 , 140, 144, 145, 156, 158 💬
12	Cbd	-	-	-	-	[11]  2 ,  6 ,  8 , 13, 46, 140, 144, 145, 156, 158, 206 💬
13	Cbd - oral solution, is known as epidyolex, and is the approved name	-	-	-	-	[1] 156 💬
14	Cbd oral solution, is known as epidyolex and is the approved name in the eu	-	-	-	-	[1] 156 💬
15	Creatine	Creatine	-	-	-	[12]  1 ,  2 ,  5 ,  6 ,  8 , 13, 46, 49, 50, 113, 156, 201 💬
16	Creatine monohydrate	Creatine	-	-	-	[4]  2 ,  8 , 113, 156 💬
17	Desipramine	Desipramine	[2] D00812, D07791 💬	[2] SLC6A2, SLC6A4 💬	[2] Serotonergic synapse, Synaptic vesicle cycle	[4]  6 , 17, 120, 156 💬
18	Dextromethorphan	Dextromethorphan	[3] D00848, D03742, D03744 💬	[6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬	[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway	[11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
19	Donepezil	Donepezil	[2] D00670, D07869 💬	[1] ACHE 💬	[2] Cholinergic synapse, Glycerophospholipid metabolism	[9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
20	Donepezil hydrochloride	Donepezil	[2] D00670, D07869 💬	[1] ACHE 💬	[2] Cholinergic synapse, Glycerophospholipid metabolism	[3]  6 , 124, 156 💬
21	Emd 128130	-	-	-	-	[2]  6 , 156 💬
22	Epi-743	-	-	-	-	[2] 21, 156 💬
23	Epidyolex	-	-	-	-	[1] 156 💬
24	Epidyolex and is the approved name in the eu	-	-	-	-	[1] 156 💬
25	Fingolimod	Fingolimod	[1] D10001 💬	[1] S1PR1 💬	[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway	[3] 13, 14, 156 💬
26	Fingolimod (fty720)	Fingolimod	[1] D10001 💬	[1] S1PR1 💬	[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway	[2] 13, 156 💬
27	Glatiramer	Glatiramer	[1] D04318 💬	[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬	[32] Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cellular senescence, Endocytosis, Epstein-Barr virus infection, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory bowel disease, Influenza A, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Phagosome, Rheumatoid arthritis, Staphylococcus aureus infection, Systemic lupus erythematosus, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis	[4]  2 , 13, 96, 156 💬
28	Glatiramer acetate	Acetate	[1] D04318 💬	[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬	[32] Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cellular senescence, Endocytosis, Epstein-Barr virus infection, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory bowel disease, Influenza A, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Phagosome, Rheumatoid arthritis, Staphylococcus aureus infection, Systemic lupus erythematosus, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis	[3] 13, 96, 156 💬
29	Glatiramer acetate (copaxone®)	Acetate	[1] D04318 💬	[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬	[32] Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cellular senescence, Endocytosis, Epstein-Barr virus infection, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory bowel disease, Influenza A, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Phagosome, Rheumatoid arthritis, Staphylococcus aureus infection, Systemic lupus erythematosus, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis	[2] 13, 156 💬
30	Gwp42003-p	-	-	-	-	[5] 140, 144, 145, 156, 158 💬
31	Human insulin	Insulin human	[2] D00085, D03230 💬	[1] INSR 💬	[22] AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway	[2] 96, 156 💬
32	Ketamine	Ketamine	[2] D00711, D08098 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway	[5] 13, 70, 113, 156, 215 💬
33	Lactobacillus plantarum	Lactobacillus plantarum	-	-	-	[3]  6 , 97, 156 💬
34	Lovastatin	Lovastatin	[1] D00359 💬	[1] HMGCR 💬	[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis	[11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
35	Nnz-2566	-	-	-	-	[2] 156, 206 💬
36	Probiotic-lactobacillus plantarum ps128	Lactobacillus plantarum	-	-	-	[1] 156 💬
37	Recombinant human insulin growth factor 1 (rhigf-1)	Insulin human	[2] D00085, D03230 💬	[1] INSR 💬	[22] AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway	[1] 156 💬
38	Rett-t	-	-	-	-	[1] 156 💬
39	Rhigf-1	-	-	-	-	[1] 156 💬
40	Risperidone	Risperidone	[1] D00426 💬	[2] DRD2, HTR2A 💬	[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway	[5]  8 , 156, 179, 187, 206 💬
41	Sarizotan	Sarizotan	-	-	-	[2]  6 , 156 💬
42	Sarizotan hydrochloride	Sarizotan	-	-	-	[2]  6 , 156 💬
43	Tocotrienol	Tocotrienol	-	-	-	[2] 156, 299 💬
44	Topiramate	Topiramate	[1] D00537 💬	[36] CA2, CA4, CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[52] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[5]  6 , 140, 144, 156, 193 💬
45	Tridecanoic acid	-	-	-	-	[1] 156 💬
46	Triheptanoin	Triheptanoin	[1] D11465 💬	-	-	[9]  2 ,  8 , 149, 156, 248, 256, 257, 317, 324 💬
47	Trofinetide	Trofinetide	-	-	-	[1] 156 💬

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