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56 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  1643368-58-4  [2] 53, 160 💬 
 2  Abatacept  Abatacept  [1] D03203 💬  [2] CD80, CD86 💬  [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis  [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 
 3  Active topical ns2 1% dermatologic cream  [1] 160 💬 
 4  Adalimumab  Adalimumab  [1] D02597 💬  [1] TNF 💬  [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 
 5  Adx-102 1% topical dermal cream (reproxalap)  [1] 160 💬 
 6  Anti-cd28dab  [3] 49, 53, 160 💬 
 7  Apply veregen ® 10 % on a randomized area and the moisturizing cream of the other side  [1] 160 💬 
 8  Atorvastatin  Atorvastatin  [3] D00258, D00887, D07474 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 
 9  Bezafibrate  Bezafibrate  [1] D01366 💬  [1] PPARA 💬  [8] Adipocytokine signaling pathway, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway  [6] 20, 93, 94, 160, 316, 324 💬 
 10  Bezalip  [3] 93, 94, 160 💬 
 11  Bezalip retard  [1] 160 💬 
 12  Bms-931699  Lulizumab pegol  [3] 49, 53, 160 💬 
 13  Bms-986142  BMS-986142  [3] 46, 53, 160 💬 
 14  Bms986142  [3] 46, 53, 160 💬 
 15  Bpr277  [1] 160 💬 
 16  Bpr277 ointment  [1] 160 💬 
 17  Bpr277 ointment (controlled application)  [1] 160 💬 
 18  Btk inhibitor  [3] 46, 53, 160 💬 
 19  Cholesterol  Cholesterol  [1] D00040 💬  [6] 19, 90, 160, 259, 261, 310 💬 
 20  Cnt-02  [1] 160 💬 
 21  Dupilumab  Dupilumab  [1] D10354 💬  [1] IL4R 💬  [8] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation  [4] 51, 98, 160, 162 💬 
 22  Dupilumab prefilled syringe  Dupilumab  [1] D10354 💬  [1] IL4R 💬  [8] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation  [1] 160 💬 
 23  Dupixent  [3] 98, 160, 162 💬 
 24  Epithelial sheet generated from transduced autologous keratinocytes using pccl-invo-sp  [1] 160 💬 
 25  Fibrate treatment  [1] 160 💬 
 26  Glucose  Dextrose, unspecified form  [15]  2 ,  6 , 13, 49, 50, 65, 75, 86, 88, 96, 160, 195, 254, 257, 299 💬 
 27  Hematopoetic stem cell transplantation  [5] 19, 65, 120, 160, 326 💬 
 28  Humira  [7] 46, 84, 96, 97, 160, 269, 271 💬 
 29  Isotretinoin  Isotretinoin  [1] D00348 💬  [2] RARA, RARB 💬  [8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer  [4] 36, 39, 159, 160 💬 
 30  Kb105  [1] 160 💬 
 31  L04ab04  [3] 46, 160, 271 💬 
 32  Lipoxygenase inhibitor  [1] 160 💬 
 33  Lovastatin  Lovastatin  [1] D00359 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 
 34  Monolaurin cream  [1] 160 💬 
 35  None  [14] 46, 65, 78, 84, 85, 96, 97, 140, 160, 161, 171, 231, 271, 299 💬 
 36  Orencia  [13] 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 160, 222, 271 💬 
 37  Other: oral glucose tolerance test  Dextrose, unspecified form  [3] 160, 195, 299 💬 
 38  Other: palliative care  [5] 19, 65, 120, 160, 326 💬 
 39  Other: vehicle  [1] 160 💬 
 40  Oxiconazole  Oxiconazole  [2] D00885, D08313 💬  [1] 160 💬 
 41  Pat  [3]  6 , 13, 160 💬 
 42  Pat-001, 0.1%  [1] 160 💬 
 43  Pat-001, 0.2%  [1] 160 💬 
 44  Pimecrolimus  Pimecrolimus  [1] D05480 💬  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬  [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway  [1] 160 💬 
 45  Pimecrolimus 1% cream  Pimecrolimus  [1] D05480 💬  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬  [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway  [1] 160 💬 
 46  Rvg 18388  [1] 160 💬 
 47  Sar231893  [2] 51, 160 💬 
 48  Secukinumab  Secukinumab  [1] D09967 💬  [1] IL17A 💬  [5] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation  [7] 13, 37, 41, 46, 160, 269, 271 💬 
 49  Simvastatin  Simvastatin  [1] D00434 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 
 50  Vehicle  [4]  6 , 36, 160, 192 💬 
 51  Vehicle of adx-102 topical dermal cream  [1] 160 💬 
 52  Veregen  [1] 160 💬 
 53  Veregen(r)  [1] 160 💬 
 54  Zileuton  Zileuton  [1] D00414 💬  [1] ALOX5 💬  [6] Arachidonic acid metabolism, Fc epsilon RI signaling pathway, Metabolic pathways, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis  [3] 85, 160, 164 💬 
 55  Zyflo  [1] 160 💬 
 56  Zyflo cr  [1] 160 💬 

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