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78 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  5-[4-[2-(5-(1-hydroxyethyl)-2- pyridinyl)ethoxy]benzyl]-2,4- thiazolidinedione hydrochloride  2,4-thiazolidinedione  -  -  -  [1] 20 💬 
 2  5-[4-[2-(5-(1-hydroxyethyl)-2-pyridinyl)ethoxy]benzyl]-2,4-thiazolidinedione hydrochloride  2,4-thiazolidinedione  -  -  -  [1] 20 💬 
 3  5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione hydrochloride  2,4-thiazolidinedione  -  -  -  [1] 20 💬 
 4  Acetylcysteine  Acetylcysteine  [1] D00221 💬  -  -  [16]  6 , 13, 19, 20, 34, 49, 51, 58, 85, 94, 111, 164, 193, 233, 298, 299 💬 
 5  Albumin  -  -  -  -  [3]  2 , 20, 51 💬 
 6  Albumin solution  -  -  -  -  [1] 20 💬 
 7  Albunorm® 5%,  -  -  -  -  [1] 20 💬 
 8  Alemtuzumab  Alemtuzumab  [1] D02802 💬  -  -  [16] 13, 15, 19, 20, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284 💬 
 9  Autologous cd34+ cells transduced with lenti-d vector encoding abcd1 cdna  -  -  -  -  [1] 20 💬 
 10  Autologous haematopoietic stem cells transduced with lentiviral vector lenti-d encoding the human abcd1 cdna  -  -  -  -  [1] 20 💬 
 11  Bezafibrate  Bezafibrate  [1] D01366 💬  [1] PPARA 💬  [8] Adipocytokine signaling pathway, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway  [6] 20, 93, 94, 160, 316, 324 💬 
 12  Biotin  Biotin  [1] D00029 💬  -  -  [5]  2 ,  8 , 10, 13, 20 💬 
 13  Busulfan  Busulfan  [1] D00248 💬  -  -  [13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬 
 14  Busulfan, cyclophosphamide, antithymocyte globulin  Busulfan  [3] D00248, D00287, D07760 💬  -  -  [2] 19, 20 💬 
 15  Cald hr-d (high-risk, regimen c)  -  -  -  -  [5] 19, 20, 125, 234, 326 💬 
 16  Cald hr-d (high-risk, regimen d)  -  -  -  -  [5] 19, 20, 125, 234, 326 💬 
 17  Cald sr-a (standard-risk, regimen a)  -  -  -  -  [5] 19, 20, 125, 234, 326 💬 
 18  Cald sr-b (standard-risk, regimen b)  -  -  -  -  [5] 19, 20, 125, 234, 326 💬 
 19  Campath  -  -  -  -  [12] 19, 20, 49, 51, 60, 62, 65, 164, 234, 283, 285, 326 💬 
 20  Campath-1h  -  -  -  -  [6] 19, 20, 60, 234, 285, 326 💬 
 21  Chenodeoxycholic acid  Chenodeoxycholic acid  [1] D00163 💬  [1] NR1H4 💬  [1] Bile secretion  [4] 20, 96, 234, 263 💬 
 22  Cholic acid  Cholic Acid  [1] D10699 💬  [1] NR1H4 💬  [1] Bile secretion  [4] 20, 234, 265, 310 💬 
 23  Cholic acids  -  -  -  -  [2] 20, 234 💬 
 24  Clofarabine  Clofarabine  [1] D03546 💬  [3] POLA1, POLA2, RRM1 💬  [6] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism  [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 
 25  Cyclophosphamide  Cyclophosphamide  [2] D00287, D07760 💬  -  -  [44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬 
 26  Cyclosporine  Cyclosporine  [1] D00184 💬  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬  [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway  [35] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 62, 63, 64, 65, 90, 95, 97, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302 💬 
 27  Cyclosporine a  Cyclosporine  [1] D00184 💬  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬  [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway  [10] 19, 20, 36, 49, 50, 53, 58, 60, 234, 283 💬 
 28  D-biotin  Biotin  [1] D00029 💬  -  -  [3] 10, 13, 20 💬 
 29  Device: cyclosporine a  Cyclosporine  [1] D00184 💬  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬  [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway  [2] 19, 20 💬 
 30  Duoc-01  -  -  -  -  [2] 19, 20 💬 
 31  Elivaldogene autotemcel  -  -  -  -  [1] 20 💬 
 32  Elivaldogenum tavalentivecum  -  -  -  -  [1] 20 💬 
 33  Glyceryl trierucate  Glyceryl Trierucate  -  -  -  [1] 20 💬 
 34  Glyceryl trierucate/glyceryl trioleate  Glyceryl Trierucate  -  -  -  [1] 20 💬 
 35  Glyceryl trioleate  Glyceryl Trioleate  -  -  -  [1] 20 💬 
 36  Hematopoietic stem cell infusion  -  -  -  -  [2] 19, 20 💬 
 37  Hematopoietic stem cell transplantation  -  -  -  -  [12] 11, 13, 14, 19, 20, 35, 46, 49, 51, 96, 234, 285 💬 
 38  Human placental derived stem cell  -  -  -  -  [4] 19, 20, 60, 284 💬 
 39  Hydroxyurea  Hydroxyurea  [1] D00341 💬  [1] RRM2 💬  [6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway  [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬 
 40  Imd  -  -  -  -  [5] 19, 20, 125, 234, 326 💬 
 41  Imd preparative regimen  -  -  -  -  [5] 19, 20, 125, 234, 326 💬 
 42  Interferon beta  Human interferon beta  -  -  -  [5] 13, 20, 26, 96, 97 💬 
 43  Lenti-d  -  -  -  -  [1] 20 💬 
 44  Lenti-d drug product  -  -  -  -  [1] 20 💬 
 45  Leriglitazone  Leriglitazone  [1] D11603 💬  [1] PPARG 💬  [9] AMPK signaling pathway, Huntington disease, Longevity regulating pathway, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer  [1] 20 💬 
 46  Lipoic acid  Lipoic acid  [2] D00048, D00086 💬  -  -  [5]  2 ,  5 , 13, 14, 20 💬 
 47  Lorenzo's oil  -  -  -  -  [1] 20 💬 
 48  Md1003  -  -  -  -  [5]  2 , 10, 13, 14, 20 💬 
 49  Md1003 100 mg capsule  -  -  -  -  [1] 20 💬 
 50  Melphalan  Melphalan  [1] D00369 💬  -  -  [15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬 
 51  Mesenchymal stem cells  -  -  -  -  [11]  2 ,  6 , 13, 20, 49, 51, 60, 96, 222, 274, 299 💬 
 52  Min-102  -  -  -  -  [2] 18, 20 💬 
 53  Modified cobratoxin  -  -  -  -  [1] 20 💬 
 54  Mycophenolate  Mycophenolic acid  [1] D05096 💬  [2] IMPDH1, IMPDH2 💬  [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism  [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 
 55  Mycophenolate mofetil  Mycophenolate mofetil  [4] D00752, D05094, D05095, D05096 💬  [2] IMPDH1, IMPDH2 💬  [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism  [32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 
 56  Mycophenylate mofetil  -  -  -  -  [2] 19, 20 💬 
 57  N-acetylcysteine  Acetylcysteine  [1] D00221 💬  -  -  [10]  6 , 13, 19, 20, 49, 58, 85, 111, 164, 299 💬 
 58  Nv1205  -  -  -  -  [1] 20 💬 
 59  Osteopetrosis haploidentical only preparative regimen  -  -  -  -  [5] 19, 20, 125, 234, 326 💬 
 60  Osteopetrosis only preparative regimen  -  -  -  -  [5] 19, 20, 125, 234, 326 💬 
 61  Pioglitazone  Pioglitazone  [2] D00945, D08378 💬  [1] PPARG 💬  [9] AMPK signaling pathway, Huntington disease, Longevity regulating pathway, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer  [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 
 62  Plerixafor  Plerixafor  [1] D08971 💬  [1] CXCR4 💬  [12] Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral protein interaction with cytokine and cytokine receptor  [5] 20, 51, 65, 285, 299 💬 
 63  Procedure: allogeneic stem cell transplantation  -  -  -  -  [3] 19, 20, 62 💬 
 64  Procedure: stem cell transplant  -  -  -  -  [5] 19, 20, 65, 164, 284 💬 
 65  Procedure: total body irradiation  -  -  -  -  [6] 19, 20, 51, 60, 65, 285 💬 
 66  Qtxew2-04-af, ew2, gc-1, qrx-431  -  -  -  -  [1] 20 💬 
 67  Rpi78m for injection  -  -  -  -  [1] 20 💬 
 68  Sobetirome  Sobetirome  [1] D09381 💬  [1] THRB 💬  [2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway  [1] 20 💬 
 69  Sobetirome (nv1205)  Sobetirome  [1] D09381 💬  [1] THRB 💬  [2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway  [1] 20 💬 
 70  Stem cell transplantation  -  -  -  -  [10] 13, 19, 20, 46, 65, 90, 125, 164, 234, 326 💬 
 71  Thalidomide  Thalidomide  [1] D00754 💬  [1] TNF 💬  [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 
 72  Thiazolidinedione  2,4-thiazolidinedione  -  -  -  [1] 20 💬 
 73  Thiotepa  Thiotepa  [1] D00583 💬  -  -  [11] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284 💬 
 74  Thiotepa--escalated dose  Thiotepa  [1] D00583 💬  -  -  [4] 19, 20, 65, 284 💬 
 75  Thiotepa--single daily dose  Thiotepa  [1] D00583 💬  -  -  [4] 19, 20, 65, 284 💬 
 76  Ursodiol  Ursodeoxycholic acid  [1] D00734 💬  [1] NR1H4 💬  [1] Bile secretion  [6]  8 , 20, 93, 97, 234, 299 💬 
 77  Vitamin d3  Cholecalciferol  [1] D00188 💬  [1] VDR 💬  [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis  [11]  6 , 13, 20, 46, 49, 53, 60, 65, 96, 97, 299 💬 
 78  Vitamin e  Vitamin E  [1] D02331 💬  -  -  [11]  2 ,  6 , 13, 20, 46, 90, 96, 97, 206, 299, 317 💬 

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