Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	(4s)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carbonitrile	-	-	-	-	[1] 231 💬
2	4-pba	-	-	-	-	[1] 231 💬
3	Acetaminophen	Acetaminophen	[1] D00217 💬	[2] PTGS1, PTGS2 💬	[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	[14] 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
4	Ads-001	-	-	-	-	[1] 231 💬
5	Aerosolized human alpha-1 antitrypsin	-	-	-	-	[1] 231 💬
6	Albumin (human) 20%, united states pharmacopeia (usp)	-	-	-	-	[1] 231 💬
7	Albuterol	Salbutamol	[1] D02147 💬	[1] ADRB2 💬	[8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway	[8] 12, 13, 86, 89, 113, 231, 256, 299 💬
8	Albuterol inhaler.	Salbutamol	[1] D02147 💬	[1] ADRB2 💬	[8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway	[2] 231, 299 💬
9	Aln-61444	-	-	-	-	[1] 231 💬
10	Aln-77412	-	-	-	-	[1] 231 💬
11	Aln-aat	-	-	-	-	[1] 231 💬
12	Aln-aat02	-	-	-	-	[1] 231 💬
13	Alpha 1-antitrypsin	Alpha-1-proteinase inhibitor	-	-	-	[2] 231, 298 💬
14	Alpha 1-proteinase inhibitor	Alpha-1-proteinase inhibitor	-	-	-	[1] 231 💬
15	Alpha 1-proteinase inhibitor (human)	Alpha-1-proteinase inhibitor	-	-	-	[1] 231 💬
16	Alpha-1 antitrypsin (aat)	-	-	-	-	[1] 231 💬
17	Alpha-1 antitrypsin (human)	-	-	-	-	[1] 231 💬
18	Alpha-1 mp	-	-	-	-	[1] 231 💬
19	Alpha-1 proteinase inhibitor (human)	-	-	-	-	[1] 231 💬
20	Alpha-1-antitrypsin	Alpha-1-proteinase inhibitor	-	-	-	[1] 231 💬
21	Alpha1-proteinase inhibitor	Alpha-1-proteinase inhibitor	-	-	-	[2] 231, 299 💬
22	Alpha1-proteinase inhibitor (human)	Alpha-1-proteinase inhibitor	-	-	-	[2] 231, 299 💬
23	Alvelestat	Alvelestat	-	-	-	[1] 231 💬
24	Alvelestat (mph966)	Alvelestat	-	-	-	[1] 231 💬
25	Alvelestat oral tablet - dose 1	Alvelestat	-	-	-	[1] 231 💬
26	Alvelestat oral tablet - dose 2	Alvelestat	-	-	-	[1] 231 💬
27	Alvelestat tosylate	Alvelestat	-	-	-	[1] 231 💬
28	Api	-	-	-	-	[2] 231, 299 💬
29	Api-aat	-	-	-	-	[1] 231 💬
30	Api-aat, ad00370, arc-aat, api drug substance	-	-	-	-	[1] 231 💬
31	Arc-aat	-	-	-	-	[1] 231 💬
32	Arc-aat injection	-	-	-	-	[1] 231 💬
33	Aro-aat	-	-	-	-	[1] 231 💬
34	Aro-aat injection	-	-	-	-	[1] 231 💬
35	Aspirin	Acetylsalicylic acid	[1] D00109 💬	[2] PTGS1, PTGS2 💬	[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	[11] 13, 22, 34, 46, 49, 51, 86, 113, 158, 210, 231 💬
36	Carbamazepine	Carbamazepine	[1] D00252 💬	[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	[2] 13, 231 💬
37	Dcr-a1at	-	-	-	-	[1] 231 💬
38	Device: abdominal ultrasound	-	-	-	-	[1] 231 💬
39	Dose of 60 mg/kg alpha1-proteinase inhibitor	Alpha-1-proteinase inhibitor	-	-	-	[1] 231 💬
40	Dose of 60 mg/kg fraction iv-1 alpha1-proteinase inhibitor	Alpha-1-proteinase inhibitor	-	-	-	[1] 231 💬
41	Drug-carbamazepine (tegretol xr)	Carbamazepine	[1] D00252 💬	[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	[1] 231 💬
42	Fentanyl	Fentanyl	[2] D00320, D01399 💬	[1] OPRM1 💬	[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction	[4] 46, 70, 215, 231 💬
43	Glassia	-	-	-	-	[1] 231 💬
44	Hyaluronic acid	Hyaluronic acid	[1] D08043 💬	-	-	[5] 46, 53, 70, 226, 231 💬
45	Hyaluronic acid inhalation solution	Hyaluronic acid	[1] D08043 💬	-	-	[1] 231 💬
46	Inbrx-101/rhaat-fc	-	-	-	-	[1] 231 💬
47	Kamada -aat for inhalation or inhaled aat (aat)	-	-	-	-	[1] 231 💬
48	Kamada-aat for inhalation	-	-	-	-	[1] 231 💬
49	Kamada-aat for inhalation, 160mg	-	-	-	-	[1] 231 💬
50	Kamada-aat for inhalation, 80mg	-	-	-	-	[1] 231 💬
51	Kamada-api	-	-	-	-	[1] 231 💬
52	Lidocaine	Lidocaine	[3] D00358, D02086, D08127 💬	[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	[10]  6 , 13, 34, 46, 51, 86, 168, 226, 231, 256 💬
53	Lorazepam	Lorazepam	[1] D00365 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	[1] 231 💬
54	Midazolam	Midazolam	[3] D00550, D00696, D05028 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	[11]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 298 💬
55	Mph966	-	-	-	-	[2] 228, 231 💬
56	None	-	-	-	-	[14] 46, 65, 78, 84, 85, 96, 97, 140, 160, 161, 171, 231, 271, 299 💬
57	None assigned	-	-	-	-	[2] 231, 299 💬
58	Octaalpha1	-	-	-	-	[1] 231 💬
59	Ondansetron	Ondansetron	[2] D00456, D00678 💬	[5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬	[2] Serotonergic synapse, Taste transduction	[3]  6 , 97, 231 💬
60	Other: liver questionnaire	-	-	-	-	[1] 231 💬
61	Other: sterile normal saline (0.9% nacl)	-	-	-	-	[1] 231 💬
62	Other: withdrawal from alpha1 antitrypsin replacement therapy	-	-	-	-	[1] 231 💬
63	Oxycodone	Oxycodone	[3] D03783, D05312, D05462 💬	[3] OPRD1, OPRK1, OPRM1 💬	[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	[7]  6 , 13, 46, 70, 226, 231, 298 💬
64	Oxycodone/acetaminophen	Acetaminophen	[4] D00217, D03783, D05312, D05462 💬	[5] OPRD1, OPRK1, OPRM1, PTGS1, PTGS2 💬	[28] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Estrogen signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, Sphingolipid signaling pathway, TNF signaling pathway, VEGF signaling pathway, cGMP-PKG signaling pathway	[1] 231 💬
65	Pba	-	-	-	-	[1] 231 💬
66	Php-303	-	-	-	-	[1] 231 💬
67	Procedure: blood draw	-	-	-	-	[5]  6 , 19, 65, 231, 299 💬
68	Procedure: blood draw.	-	-	-	-	[2] 231, 299 💬
69	Procedure: history and physical	-	-	-	-	[1] 231 💬
70	Procedure: history and physical exam.	-	-	-	-	[2] 231, 299 💬
71	Procedure: intravenous catheter	-	-	-	-	[1] 231 💬
72	Procedure: liver biopsy	-	-	-	-	[3] 171, 231, 240 💬
73	Procedure: pulmonary function testing.	-	-	-	-	[2] 231, 299 💬
74	Prolastin	-	-	-	-	[3] 231, 298, 299 💬
75	Prolastin-c	-	-	-	-	[2] 231, 298 💬
76	Prolastin-c, 120 mg/kg	-	-	-	-	[1] 231 💬
77	Prolastin-c, 60 mg/kg	-	-	-	-	[1] 231 💬
78	Raav1-cb-haat	-	-	-	-	[1] 231 💬
79	Recombinant adeno-associated viral vector expressing the human alpha-1-antitrypsin gene	Alpha-1-proteinase inhibitor	-	-	-	[1] 231 💬
80	Retinoic acid	Tretinoin	[1] D00094 💬	[3] PML, RARA, RARB 💬	[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis	[2] 94, 231 💬
81	Retinoic acid receptor gamma agonist	Tretinoin	[1] D00094 💬	[3] PML, RARA, RARB 💬	[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis	[1] 231 💬
82	Ro3300074	-	-	-	-	[1] 231 💬
83	Vx-814	-	-	-	-	[1] 231 💬
84	Vx-864	-	-	-	-	[1] 231 💬
85	Vx864	-	-	-	-	[1] 231 💬

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