Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	1-deoxynojirimycin	Duvoglustat	[1] D09605 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
2	1-deoxynojirimycin hydrochloride	Duvoglustat	[1] D09605 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
3	A-glucosidasi acida umana ricombinante coniugata con multiple copie di bis-mannosio-6- fosfato-tetra-mannosio glicano sintetico (neogaa)	Avalglucosidase alfa	[1] D11744 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
4	Aav2/8lsphgaa	-	-	-	-	[1] 256 💬
5	Acetaminophen	Acetaminophen	[1] D00217 💬	[2] PTGS1, PTGS2 💬	[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	[14] 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
6	Albuterol	Salbutamol	[1] D02147 💬	[1] ADRB2 💬	[8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway	[8] 12, 13, 86, 89, 113, 231, 256, 299 💬
7	Aldurazyme (laronidase)	Laronidase	[1] D04670 💬	[1] IDUA 💬	[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways	[2] 19, 256 💬
8	Alglucosidase alfa	Alglucosidase alfa	[1] D03207 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
9	Alglucosidase alfa (genetical recombination)	Alglucosidase alfa	[1] D03207 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
10	Alglucosidase alfa (gz419829)	Alglucosidase alfa	[1] D03207 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
11	Alglucosidase alfa (myozyme)	Alglucosidase alfa	[1] D03207 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
12	Alglucosidase alfa (recombinant human acid alpha-glucosidase [rhgaa])	Alglucosidase alfa	[1] D03207 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
13	Alglucosidase alfa gz419829	Alglucosidase alfa	[1] D03207 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
14	Alglucosidase alpha	-	-	-	-	[1] 256 💬
15	Alpha-glucosidase	Alglucosidase alfa	[1] D03207 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
16	At2220	AT2220	-	-	-	[1] 256 💬
17	At2221	-	-	-	-	[1] 256 💬
18	At2221 65 mg formulated capsules	-	-	-	-	[1] 256 💬
19	At845	-	-	-	-	[1] 256 💬
20	Atb200	-	-	-	-	[1] 256 💬
21	Avalglucosidase alfa	Avalglucosidase alfa	[1] D11744 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
22	Avalglucosidase alfa (neogaa)	Avalglucosidase alfa	[1] D11744 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
23	Avalglucosidase alfa gz402666	Avalglucosidase alfa	[1] D11744 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
24	Avalglucosidase alfa(gz402666)	Avalglucosidase alfa	[1] D11744 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
25	Beta-hydroxybuturate esters	-	-	-	-	[1] 256 💬
26	Bmn 701	-	-	-	-	[1] 256 💬
27	Bortezomib	Bortezomib	[1] D03150 💬	[1] PSMB5 💬	[8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia	[15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬
28	Cipaglucosidase alfa	-	-	-	-	[1] 256 💬
29	Clenbuterol	Clenbuterol	[1] D07713 💬	[1] ADRB2 💬	[8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway	[4]  1 ,  2 ,  6 , 256 💬
30	Cyclophosphamide	Cyclophosphamide	[2] D00287, D07760 💬	-	-	[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
31	Cyclophosphamide monohydrate	Cyclophosphamide	[2] D00287, D07760 💬	-	-	[4] 13, 60, 96, 256 💬
32	Deoxynojirimycin	Duvoglustat	[1] D09605 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
33	Deprakine	-	-	-	-	[1] 256 💬
34	Diphenhydramine	Diphenhydramine	[6] D00300, D00669, D02419, D03285, D03360, D03854 💬	[1] HRH1 💬	[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
35	Duvoglustat	Duvoglustat	[1] D09605 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
36	Duvoglustat hcl	Duvoglustat	[1] D09605 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
37	Duvoglustat hydrochloride	Duvoglustat	[1] D09605 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
38	Enzyme replacement agent	-	-	-	-	[1] 256 💬
39	Epilim	-	-	-	-	[1] 256 💬
40	Epilim chrono 200 controlled released tablets	-	-	-	-	[1] 256 💬
41	Epilim chrono 300 controlled released tablets	-	-	-	-	[1] 256 💬
42	Epilim chrono 500 controlled released tablets	-	-	-	-	[1] 256 💬
43	Filgrastim	Filgrastim	[1] D03235 💬	[1] CSF3R 💬	[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer	[27]  2 ,  6 , 13, 25, 26, 28, 34, 35, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
44	Genetic: recombinant adeno-associated virus acid alpha-glucosidase	Alglucosidase alfa	[1] D03207 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
45	Gilt-rhgaa	-	-	-	-	[1] 256 💬
46	Glucosidase alfa	-	-	-	-	[1] 256 💬
47	Glycosade	-	-	-	-	[3] 65, 256, 257 💬
48	Gz402666	-	-	-	-	[1] 256 💬
49	Intravenous immune globulin	-	-	-	-	[1] 256 💬
50	Ketocal 4:1 liquid nutricia (intervention)	-	-	-	-	[1] 256 💬
51	Laronidase	Laronidase	[1] D04670 💬	[1] IDUA 💬	[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways	[2] 19, 256 💬
52	Lidocaine	Lidocaine	[3] D00358, D02086, D08127 💬	[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	[10]  6 , 13, 34, 46, 51, 86, 168, 226, 231, 256 💬
53	Lmx 4 topical cream	-	-	-	-	[1] 256 💬
54	Low carbohydrate ketogenic diet	-	-	-	-	[1] 256 💬
55	Lumizyme	-	-	-	-	[1] 256 💬
56	Lumizyme®	-	-	-	-	[1] 256 💬
57	Mannose	Mannose	-	-	-	[2] 13, 256 💬
58	Methotrexate	Methotrexate	[2] D00142, D02115 💬	[2] DHFR, DHFR2 💬	[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate	[35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
59	Methotrexate sodium	Methotrexate	[2] D00142, D02115 💬	[2] DHFR, DHFR2 💬	[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate	[2] 46, 256 💬
60	Miglustat	Miglustat	[1] D05032 💬	[1] UGCG 💬	[2] Metabolic pathways, Sphingolipid metabolism	[3] 19, 256, 299 💬
61	Miglustat (at2221)	Miglustat	[1] D05032 💬	[1] UGCG 💬	[2] Metabolic pathways, Sphingolipid metabolism	[1] 256 💬
62	Myozyme	-	-	-	-	[1] 256 💬
63	Myozyme 50 mg powder for concentrate for solution for infusion	-	-	-	-	[1] 256 💬
64	Myozyme®	-	-	-	-	[1] 256 💬
65	Myozyme® (alglucosidase alfa)	Alglucosidase alfa	[1] D03207 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
66	N.a.	-	-	-	-	[10]  3 ,  6 ,  8 , 13, 46, 96, 97, 240, 256, 271 💬
67	Neo-gaa	-	-	-	-	[1] 256 💬
68	Neogaa	Avalglucosidase alfa	[1] D11744 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
69	Neogaa or avalglucosidase alfa	Avalglucosidase alfa	[1] D11744 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
70	Other: no treatment	-	-	-	-	[2] 53, 256 💬
71	Other: rmst	-	-	-	-	[1] 256 💬
72	Other: saline	-	-	-	-	[8]  2 ,  6 , 46, 97, 98, 256, 274, 301 💬
73	Phosphate	Phosphate ion	-	-	-	[30]  2 ,  3 , 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 256, 276, 283, 284, 285, 286, 299 💬
74	Plecebo	-	-	-	-	[1] 256 💬
75	Pyridostigmine	Pyridostigmine	[1] D00487 💬	[1] ACHE 💬	[2] Cholinergic synapse, Glycerophospholipid metabolism	[4]  3 ,  6 , 11, 256 💬
76	Pyridostigmine bromide	Pyridostigmine	[1] D00487 💬	[1] ACHE 💬	[2] Cholinergic synapse, Glycerophospholipid metabolism	[3]  3 ,  6 , 256 💬
77	Raav1-cmv-gaa (study agent) administration	-	-	-	-	[1] 256 💬
78	Rapamycin	Sirolimus	[1] D00753 💬	[1] MTOR 💬	[50] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway	[18]  2 , 15, 34, 35, 46, 49, 51, 60, 61, 67, 86, 89, 96, 157, 158, 256, 278, 279 💬
79	Recombinant human ?-glucosidase conjugated with synthetic bismannose-6-phosphate-man6 glycan	Phosphate ion	-	-	-	[1] 256 💬
80	Recombinant human a-glucosidase conjugated with multiple copies of synthetic bis-mannose-6-phosphate-tetra-mannose glycan (neogaa)	Avalglucosidase alfa	[1] D11744 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
81	Recombinant human a-glucosidase conjugated with multiple copies of synthetic bis-mannose-6-phosphate-tetra-mannose glycan avalglucosidase alfa (neogaa)	Avalglucosidase alfa	[1] D11744 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
82	Recombinant human acid alfa-glucosidase	-	-	-	-	[1] 256 💬
83	Recombinant human acid alfa-glucosidase (atb200)	-	-	-	-	[1] 256 💬
84	Recombinant human acid alfa-glucosidase (rhgaa)	-	-	-	-	[1] 256 💬
85	Recombinant human acid alpha-glucosidase (rhgaa)	Alglucosidase alfa	[1] D03207 💬	[1] GAA 💬	[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism	[1] 256 💬
86	Ren001	ReN001	-	-	-	[1] 256 💬
87	Reveglucosidase alfa	-	-	-	-	[1] 256 💬
88	Reveglucosidase alpha	-	-	-	-	[1] 256 💬
89	Rhgaa	-	-	-	-	[1] 256 💬
90	Rhgaa, acid alpha glucosidase	-	-	-	-	[1] 256 💬
91	Rituxan	-	-	-	-	[4] 46, 60, 256, 288 💬
92	Rituximab	Rituximab	[1] D02994 💬	[1] MS4A1 💬	[1] Hematopoietic cell lineage	[47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
93	Salbutamol	Salbutamol	[1] D02147 💬	[1] ADRB2 💬	[8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway	[9]  3 , 11, 49, 85, 86, 111, 228, 256, 299 💬
94	Sodium valproate	Valproic acid	[1] D00399 💬	[7] ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	[4]  2 , 90, 102, 256 💬
95	Spk-3006	-	-	-	-	[1] 256 💬
96	Ss-hydroxybuturate esters	-	-	-	-	[1] 256 💬
97	Triheptanoin	Triheptanoin	[1] D11465 💬	-	-	[9]  2 ,  8 , 149, 156, 248, 256, 257, 317, 324 💬
98	Ux007	-	-	-	-	[4]  8 , 248, 256, 257 💬
99	Val-1221	-	-	-	-	[1] 256 💬
100	Valproate	Valproic acid	[1] D00399 💬	[7] ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	[6]  2 ,  3 , 90, 102, 233, 256 💬
101	Valproic acid	Valproic acid	[1] D00399 💬	[7] ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	[10]  3 ,  5 , 26, 34, 65, 89, 90, 222, 256, 331 💬
102	Zavesca	-	-	-	-	[3] 19, 256, 299 💬
103	Zavesca® prescription	-	-	-	-	[1] 256 💬

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