Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	(s)-4,5-dihydro-2-[2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazo	-	-	-	-	[1] 284 💬
2	(s)-4,5-dihydro-2-[2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylate magnesium hydroxide	Hydroxide ion	[1] D00731 💬	-	-	[1] 284 💬
3	(s)-4,5-dihydro-2[hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-m	-	-	-	-	[1] 284 💬
4	(s)-4,5-dihydro-2[hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylate magnesium hydroxide	Hydroxide ion	[1] D00731 💬	-	-	[1] 284 💬
5	Abatacept	Abatacept	[1] D03203 💬	[2] CD80, CD86 💬	[12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
6	Alefacept	Alefacept	[1] D02800 💬	[1] CD58 💬	[2] Cell adhesion molecules, Epstein-Barr virus infection	[6] 37, 60, 65, 164, 284, 285 💬
7	Alemtuzumab	Alemtuzumab	[1] D02802 💬	-	-	[16] 13, 15, 19, 20, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284 💬
8	Alpha beta depletion	-	-	-	-	[2] 60, 284 💬
9	Anti-thymocyte globulin	-	-	-	-	[18] 11, 13, 14, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 164, 283, 284, 285 💬
10	Antithymocyte globulin	-	-	-	-	[3] 60, 65, 284 💬
11	Bpx-501 t cells	-	-	-	-	[4] 65, 284, 285, 326 💬
12	Busulfan	Busulfan	[1] D00248 💬	-	-	[13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
13	Busulfan, cyclophosphamide, atg, gcsf	Busulfan	[3] D00248, D00287, D07760 💬	-	-	[2] 65, 284 💬
14	Busulfan, fludarabine, atg, tli	Busulfan	[3] D00248, D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[2] 65, 284 💬
15	Campath, fludarabine, cyclophosphamide	Cyclophosphamide	[4] D00287, D01907, D07760, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[2] 65, 284 💬
16	Cd3/cd19 depleted leukocytes	-	-	-	-	[1] 284 💬
17	Cd34 stem cell selection therapy	-	-	-	-	[3] 60, 65, 284 💬
18	Cd45ra depleted leukocytes	-	-	-	-	[1] 284 💬
19	Cyclophosphamide	Cyclophosphamide	[2] D00287, D07760 💬	-	-	[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
20	Cyclophosphamide dose level 1	Cyclophosphamide	[2] D00287, D07760 💬	-	-	[2] 65, 284 💬
21	Cyclophosphamide dose level 2	Cyclophosphamide	[2] D00287, D07760 💬	-	-	[2] 65, 284 💬
22	Cyclophosphamide dose level 3	Cyclophosphamide	[2] D00287, D07760 💬	-	-	[2] 65, 284 💬
23	Cyclophosphamide dose level 4	Cyclophosphamide	[2] D00287, D07760 💬	-	-	[2] 65, 284 💬
24	Cyclosporine	Cyclosporine	[1] D00184 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	[32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	[35] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 62, 63, 64, 65, 90, 95, 97, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302 💬
25	Daclizumab	Daclizumab	[1] D03639 💬	[1] IL2RA 💬	[11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor	[7] 13, 56, 60, 65, 97, 283, 284 💬
26	Deferasirox	Deferasirox	[1] D03669 💬	-	-	[3] 254, 284, 286 💬
27	Deferitazole	Deferitazole	[1] D10388 💬	-	-	[1] 284 💬
28	Deferoxamine	Deferoxamine	[2] D01186, D03670 💬	-	-	[2] 284, 286 💬
29	Desferal	-	-	-	-	[2] 284, 286 💬
30	Dfo	-	-	-	-	[3] 46, 284, 286 💬
31	Eltrombopag	Eltrombopag	[1] D03978 💬	-	-	[5] 60, 63, 65, 284, 285 💬
32	Enriched hematopoetic stem cell infusion	-	-	-	-	[3] 13, 19, 284 💬
33	Exjade	-	-	-	-	[3] 254, 284, 286 💬
34	Fbs0701	-	-	-	-	[1] 284 💬
35	Fbs0701 capsule	-	-	-	-	[1] 284 💬
36	Fbs0701/ssp004184	-	-	-	-	[1] 284 💬
37	Filgrastim	Filgrastim	[1] D03235 💬	[1] CSF3R 💬	[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer	[27]  2 ,  6 , 13, 25, 26, 28, 34, 35, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
38	Fludarabine	Fludarabine	[2] D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
39	Fludarabine monophosphate	Fludarabine	[2] D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[3] 65, 284, 326 💬
40	Fludarabine phosphate	Fludarabine	[2] D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[11] 28, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285 💬
41	G-csf	Filgrastim	[1] D03235 💬	[1] CSF3R 💬	[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer	[16]  2 ,  6 , 11, 13, 16, 47, 49, 51, 60, 62, 65, 85, 96, 284, 285, 331 💬
42	Human placental derived stem cell	-	-	-	-	[4] 19, 20, 60, 284 💬
43	Hydroxide	Hydroxide ion	-	-	-	[4] 46, 96, 97, 284 💬
44	Hydroxyurea	Hydroxyurea	[1] D00341 💬	[1] RRM2 💬	[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway	[8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
45	Icl670	-	-	-	-	[3] 60, 284, 286 💬
46	Iron	Iron	-	-	-	[5] 18, 96, 97, 254, 284 💬
47	Iron chelating agents	-	-	-	-	[1] 284 💬
48	L-leucine	Leucine	[1] D00030 💬	-	-	[1] 284 💬
49	Lenalidomide	Lenalidomide	[1] D04687 💬	[1] TNF 💬	[65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	[7] 16, 26, 28, 34, 49, 284, 300 💬
50	Leucine	Leucine	[1] D00030 💬	-	-	[10]  5 ,  6 ,  7 , 19, 96, 97, 127, 283, 284, 299 💬
51	Magnesium	Magnesium	-	-	-	[16]  6 , 11, 13, 46, 64, 70, 93, 97, 166, 225, 235, 284, 291, 296, 297, 298 💬
52	Magnesium hydroxide	Hydroxide ion	[1] D00731 💬	-	-	[1] 284 💬
53	Melphalan	Melphalan	[1] D00369 💬	-	-	[15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬
54	Mesenchymal stromal cells	Human Umbilical Cord Mesenchymal Stem Cells	-	-	-	[9]  2 , 36, 49, 51, 60, 96, 97, 274, 284 💬
55	Methotrexate	Methotrexate	[2] D00142, D02115 💬	[2] DHFR, DHFR2 💬	[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate	[35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
56	Methylprednisolone	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
57	Mycophenolate	Mycophenolic acid	[1] D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
58	Mycophenolate mofetil	Mycophenolate mofetil	[4] D00752, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
59	Myeloablative preparative regimen	-	-	-	-	[3] 62, 65, 284 💬
60	Other: laboratory biomarker analysis	-	-	-	-	[21] 11, 13, 14, 16, 26, 28, 34, 49, 51, 60, 62, 65, 89, 96, 97, 232, 283, 284, 285, 298, 331 💬
61	Phosphate	Phosphate ion	-	-	-	[30]  2 ,  3 , 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 256, 276, 283, 284, 285, 286, 299 💬
62	Prednisone	Prednisone	[1] D00473 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[47]  2 ,  6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
63	Procedure: allogeneic bone marrow transplantation	-	-	-	-	[6] 60, 65, 96, 164, 284, 285 💬
64	Procedure: allogeneic hematopoietic stem cell transplantation	-	-	-	-	[8] 28, 51, 60, 62, 65, 164, 284, 285 💬
65	Procedure: bone marrow transplantation	-	-	-	-	[4] 51, 60, 284, 285 💬
66	Procedure: leukapheresis	-	-	-	-	[5] 49, 51, 96, 284, 285 💬
67	Procedure: peripheral blood stem cell transplantation	-	-	-	-	[11] 11, 13, 14, 28, 51, 60, 62, 65, 283, 284, 285 💬
68	Procedure: radiation therapy	-	-	-	-	[3] 13, 284, 285 💬
69	Procedure: stem cell infusion	-	-	-	-	[5] 28, 60, 65, 284, 285 💬
70	Procedure: stem cell transplant	-	-	-	-	[5] 19, 20, 65, 164, 284 💬
71	Procedure: total lymphoid irradiation	-	-	-	-	[3] 65, 284, 326 💬
72	Procedure: umbilical cord blood transplantation	-	-	-	-	[5] 60, 65, 284, 285, 326 💬
73	Radiation: radiation therapy	-	-	-	-	[5] 34, 60, 65, 284, 285 💬
74	Radiation: total body irradiation	-	-	-	-	[7] 36, 49, 51, 60, 65, 283, 284 💬
75	Radiation: total-body irradiation	-	-	-	-	[9] 28, 51, 60, 62, 65, 96, 283, 284, 285 💬
76	Reduced intensity preparative regimen	-	-	-	-	[3] 62, 65, 284 💬
77	Reduced toxicity ablative regimen	-	-	-	-	[3] 62, 65, 284 💬
78	Rimiducid	Rimiducid	[1] D11195 💬	[1] CASP9 💬	[34] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway	[6] 19, 60, 65, 284, 285, 326 💬
79	Rituximab	Rituximab	[1] D02994 💬	[1] MS4A1 💬	[1] Hematopoietic cell lineage	[47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
80	Rivogenlecleucel	-	-	-	-	[6] 19, 60, 65, 284, 285, 326 💬
81	Sotatercept	Sotatercept	[1] D09670 💬	[1] ACVR2A 💬	[4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway	[2] 86, 284 💬
82	Sotatercept with prednisone boost	Prednisone	[2] D00473, D09670 💬	[2] ACVR2A, NR3C1 💬	[5] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Neuroactive ligand-receptor interaction, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway	[1] 284 💬
83	Ssp-004184 100 mg	-	-	-	-	[1] 284 💬
84	Ssp-004184 100 mg capsule	-	-	-	-	[1] 284 💬
85	Ssp-004184 250 mg	-	-	-	-	[1] 284 💬
86	Ssp-004184 250 mg capsule	-	-	-	-	[1] 284 💬
87	Ssp-004184 375 mg	-	-	-	-	[1] 284 💬
88	Ssp-004184 375 mg capsule	-	-	-	-	[1] 284 💬
89	Ssp-004184 50 mg	-	-	-	-	[1] 284 💬
90	Ssp-004184 50 mg capsule	-	-	-	-	[1] 284 💬
91	Ssp-004184 500 mg	-	-	-	-	[1] 284 💬
92	Ssp-004184 500 mg capsule	-	-	-	-	[1] 284 💬
93	Ssp-004184aq 100 mg	-	-	-	-	[1] 284 💬
94	Ssp-004184aq 100 mg capsule	-	-	-	-	[1] 284 💬
95	Ssp-004184aq 200 mg	-	-	-	-	[1] 284 💬
96	Ssp-004184aq 200 mg capsule	-	-	-	-	[1] 284 💬
97	Ssp-004184aq 250 mg	-	-	-	-	[1] 284 💬
98	Ssp-004184aq 250 mg capsule	-	-	-	-	[1] 284 💬
99	Ssp-004184aq 375 mg	-	-	-	-	[1] 284 💬
100	Ssp-004184aq 375 mg capsule	-	-	-	-	[1] 284 💬
101	Ssp-004184aq 50 mg	-	-	-	-	[1] 284 💬
102	Ssp-004184aq 50 mg capsule	-	-	-	-	[1] 284 💬
103	Tacrolimus	Tacrolimus	[2] D00107, D08556 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	[32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	[32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
104	Thiotepa	Thiotepa	[1] D00583 💬	-	-	[11] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284 💬
105	Thiotepa--escalated dose	Thiotepa	[1] D00583 💬	-	-	[4] 19, 20, 65, 284 💬
106	Thiotepa--single daily dose	Thiotepa	[1] D00583 💬	-	-	[4] 19, 20, 65, 284 💬
107	Trifluoperazine	Trifluoperazine	[3] D00799, D01448, D08636 💬	[1] DRD2 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[2] 283, 284 💬

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