Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	2011-2012 seasonal flu vaccine intramuscular	-	-	-	-	[2]  3 , 113 💬
2	2011-2012 seasonal flu vaccine subcutaneous	-	-	-	-	[2]  3 , 113 💬
3	4-aminopyridine	Dalfampridine	[1] D04127 💬	[4] KCNA4, KCNC3, KCND2, KCND3 💬	[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia	[2]  3 , 13 💬
4	4-cholesten-3-one, oxime	-	-	-	-	[2]  2 ,  3  💬
5	4-cholesten-3-one,oxime	-	-	-	-	[1]  3  💬
6	Adipose derived mesenchymal stem cell	-	-	-	-	[1]  3  💬
7	Air	-	-	-	-	[7]  3 , 51, 58, 85, 97, 193, 299 💬
8	Amifampridine	Amifampridine	[1] D10228 💬	[4] KCNA4, KCNC3, KCND2, KCND3 💬	[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia	[3]  3 , 11, 12 💬
9	Amifampridine phosphate	Amifampridine	[1] D10228 💬	[4] KCNA4, KCNC3, KCND2, KCND3 💬	[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia	[3]  3 , 11, 12 💬
10	Amifampridine phosphate 10 mg oral tablet	Amifampridine	[1] D10228 💬	[4] KCNA4, KCNC3, KCND2, KCND3 💬	[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia	[1]  3  💬
11	Avxs-101	-	-	-	-	[1]  3  💬
12	Avxs-101 (previously known as scaav9.cb.smn)	-	-	-	-	[1]  3  💬
13	Biocarn	-	-	-	-	[1]  3  💬
14	Branaplam	Branaplam	-	-	-	[1]  3  💬
15	Celecoxib	Celecoxib	[1] D00567 💬	[1] PTGS2 💬	[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	[9]  2 ,  3 , 34, 46, 70, 89, 161, 171, 271 💬
16	Gh	-	-	-	-	[1]  3  💬
17	Human anti-promyostatin monoclonal antibody	-	-	-	-	[1]  3  💬
18	Hydroxyurea	Hydroxyurea	[1] D00341 💬	[1] RRM2 💬	[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway	[8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
19	Isis 396443	-	-	-	-	[1]  3  💬
20	Isis 396443 (biib058)	-	-	-	-	[1]  3  💬
21	Isis 396443, biib058	-	-	-	-	[1]  3  💬
22	Itraconazole	Itraconazole	[1] D00350 💬	-	-	[4]  3 , 65, 227, 299 💬
23	Leuprolide	Leuprolide	[2] D00989, D08113 💬	[1] GNRHR 💬	[2] GnRH signaling pathway, Neuroactive ligand-receptor interaction	[5]  1 ,  2 ,  3 , 51, 76 💬
24	Levocarnitine	Levocarnitine	[3] D02030, D02176, D04713 💬	-	-	[3]  3 , 53, 97 💬
25	Lmi070	-	-	-	-	[1]  3  💬
26	Mestinon	-	-	-	-	[3]  3 ,  6 , 11 💬
27	Midazolam	Midazolam	[3] D00550, D00696, D05028 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	[11]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 298 💬
28	N.a.	-	-	-	-	[10]  3 ,  6 ,  8 , 13, 46, 96, 97, 240, 256, 271 💬
29	Nerve growth factor	Nerve Growth Factor	-	-	-	[2]  3 , 90 💬
30	Norditropin simplexx	-	-	-	-	[4]  3 , 78, 193, 195 💬
31	Norditropin simplexx 15 mg/1.5 ml	-	-	-	-	[1]  3  💬
32	Nursinersen	-	-	-	-	[1]  3  💬
33	Nusinersen	Nusinersen	[1] D10881 💬	[1] SMN2 💬	[1] RNA transport	[1]  3  💬
34	Nusinersen injectable product	Nusinersen	[1] D10881 💬	[1] SMN2 💬	[1] RNA transport	[1]  3  💬
35	Nusinersen sodium	Nusinersen	[1] D10881 💬	[1] SMN2 💬	[1] RNA transport	[1]  3  💬
36	Nusinersen treatments	Nusinersen	[1] D10881 💬	[1] SMN2 💬	[1] RNA transport	[1]  3  💬
37	Olesoxime	-	-	-	-	[2]  2 ,  3  💬
38	Onasemnogene abeparvovec	Onasemnogene abeparvovec	[1] D11559 💬	[1] SMN1 💬	[1] RNA transport	[1]  3  💬
39	Onasemnogene abeparvovec-xioi	Onasemnogene abeparvovec	[1] D11559 💬	[1] SMN1 💬	[1] RNA transport	[1]  3  💬
40	Orfiril saft	-	-	-	-	[1]  3  💬
41	Other: monthly assessments of functional motor abilities by a trained therapist	-	-	-	-	[1]  3  💬
42	Other: prospective observational registry	-	-	-	-	[1]  3  💬
43	Paracetamol	Acetaminophen	[1] D00217 💬	[2] PTGS1, PTGS2 💬	[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	[5]  3 ,  6 , 13, 35, 46 💬
44	Paracetamol 120mg/5ml oral suspension	Acetaminophen	[1] D00217 💬	[2] PTGS1, PTGS2 💬	[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	[1]  3  💬
45	Phenylbutyrate	Phenylbutyric acid	[1] D05868 💬	-	-	[11]  2 ,  3 ,  6 ,  8 , 15, 93, 94, 244, 251, 297, 299 💬
46	Phosphate	Phosphate ion	-	-	-	[30]  2 ,  3 , 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 256, 276, 283, 284, 285, 286, 299 💬
47	Placebo	-	-	-	-	[26]  3 ,  5 ,  6 , 13, 14, 37, 40, 46, 49, 50, 51, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276 💬
48	Procedure: air stacking manuever	-	-	-	-	[1]  3  💬
49	Procedure: sham procedure	-	-	-	-	[1]  3  💬
50	Pyridostigmine	Pyridostigmine	[1] D00487 💬	[1] ACHE 💬	[2] Cholinergic synapse, Glycerophospholipid metabolism	[4]  3 ,  6 , 11, 256 💬
51	Pyridostigmine bromide	Pyridostigmine	[1] D00487 💬	[1] ACHE 💬	[2] Cholinergic synapse, Glycerophospholipid metabolism	[3]  3 ,  6 , 256 💬
52	Reldesemtiv	Reldesemtiv	[1] D11363 💬	[1] TNNC2 💬	[1] Calcium signaling pathway	[2]  2 ,  3  💬
53	Reldesemtiv 150 mg	Reldesemtiv	[1] D11363 💬	[1] TNNC2 💬	[1] Calcium signaling pathway	[1]  3  💬
54	Reldesemtiv 450 mg	Reldesemtiv	[1] D11363 💬	[1] TNNC2 💬	[1] Calcium signaling pathway	[1]  3  💬
55	Riluzole	Riluzole	[1] D00775 💬	[14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway	[8]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 206 💬
56	Risdiplam	Risdiplam	[1] D11406 💬	[1] SMN2 💬	[1] RNA transport	[1]  3  💬
57	Ro6885247	-	-	-	-	[1]  3  💬
58	Ro6885247/f02	-	-	-	-	[1]  3  💬
59	Ro6885247/f03	-	-	-	-	[1]  3  💬
60	Ro7034067	-	-	-	-	[1]  3  💬
61	Ro7034067 / f12	-	-	-	-	[1]  3  💬
62	Ro7034067 / f13	-	-	-	-	[1]  3  💬
63	Ro7034067/f06 + solvente (ro	-	-	-	-	[1]  3  💬
64	Ro7034067/f06 with solvent (ro7034067/f08)	-	-	-	-	[1]  3  💬
65	Ro7034067/f07 + solvente (ro	-	-	-	-	[1]  3  💬
66	Ro7034067/f07 with solvent (ro7034067/f09)	-	-	-	-	[1]  3  💬
67	Ro7034067/f12	-	-	-	-	[1]  3  💬
68	Ro7034067/f13	-	-	-	-	[1]  3  💬
69	Ro7090919	-	-	-	-	[1]  3  💬
70	Rvg 03820	-	-	-	-	[1]  3  💬
71	Salbutamol	Salbutamol	[1] D02147 💬	[1] ADRB2 💬	[8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway	[9]  3 , 11, 49, 85, 86, 111, 228, 256, 299 💬
72	Sesame oil	Sesame oil	[1] D03314 💬	-	-	[1]  3  💬
73	Sesame oil, refined	Sesame oil	[1] D03314 💬	-	-	[1]  3  💬
74	Smart	-	-	-	-	[1]  3  💬
75	Sodium phenylbutyrate	Phenylbutyric acid	[1] D05868 💬	-	-	[4]  2 ,  3 ,  8 , 251 💬
76	Sodium phenylbutyrate (napb)	Phenylbutyric acid	[1] D05868 💬	-	-	[1]  3  💬
77	Somatotropin	Somatotropin	[1] D02691 💬	[1] GHR 💬	[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway	[3]  3 , 78, 236 💬
78	Somatropin	Somatotropin	[1] D02691 💬	[1] GHR 💬	[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway	[16]  2 ,  3 , 19, 46, 74, 75, 78, 96, 113, 187, 193, 195, 265, 274, 276, 299 💬
79	Spinraza	-	-	-	-	[1]  3  💬
80	Srk-015	-	-	-	-	[1]  3  💬
81	Survival of motor neuron 2 (smn2) splicing modulator antisense oligonucleotide	-	-	-	-	[1]  3  💬
82	Testosterone	Testosterone	[6] D00075, D00957, D00958, D00959, D06085, D06087 💬	[1] AR 💬	[3] Oocyte meiosis, Pathways in cancer, Prostate cancer	[8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
83	Tro19622	TRO19622	-	-	-	[3]  2 ,  3 , 13 💬
84	Valproate	Valproic acid	[1] D00399 💬	[7] ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	[6]  2 ,  3 , 90, 102, 233, 256 💬
85	Valproate sodium	Valproic acid	[1] D00399 💬	[7] ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	[1]  3  💬
86	Valproate, levocarnitine	Levocarnitine	[4] D00399, D02030, D02176, D04713 💬	[7] ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	[1]  3  💬
87	Valproic acid	Valproic acid	[1] D00399 💬	[7] ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	[10]  3 ,  5 , 26, 34, 65, 89, 90, 222, 256, 331 💬
88	Valproic acid (vpa)	Valproic acid	[1] D00399 💬	[7] ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	[1]  3  💬
89	Valproic acid and levocarnitine	Levocarnitine	[4] D00399, D02030, D02176, D04713 💬	[7] ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	[1]  3  💬
90	Volmax*30cpr 4mg r.p.	-	-	-	-	[1]  3  💬
91	Vpa	-	-	-	-	[1]  3  💬
92	Zolgensma	-	-	-	-	[1]  3  💬

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