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50 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  Actimmune  [1] 326 💬 
 2  Actimmune registry  [1] 326 💬 
 3  Ap1903  [3] 60, 285, 326 💬 
 4  Ap1903 a594  [3] 60, 285, 326 💬 
 5  Bpx-501  [3] 60, 285, 326 💬 
 6  Bpx-501 cells  [3] 60, 285, 326 💬 
 7  Bpx-501 t cells  [4] 65, 284, 285, 326 💬 
 8  Busulfan  Busulfan  [1] D00248 💬  [13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬 
 9  Busulfan, cyclophosphamide, thymoglobulin, fludarabine (conditioning regimen)  Antithymocyte immunoglobulin (rabbit)  [5] D00248, D00287, D01907, D07760, D07966 💬  [1] RRM1 💬  [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism  [1] 326 💬 
 10  Calcitriol  Calcitriol  [1] D00129 💬  [1] VDR 💬  [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis  [8] 37, 46, 49, 66, 96, 158, 235, 326 💬 
 11  Cald hr-d (high-risk, regimen c)  [5] 19, 20, 125, 234, 326 💬 
 12  Cald hr-d (high-risk, regimen d)  [5] 19, 20, 125, 234, 326 💬 
 13  Cald sr-a (standard-risk, regimen a)  [5] 19, 20, 125, 234, 326 💬 
 14  Cald sr-b (standard-risk, regimen b)  [5] 19, 20, 125, 234, 326 💬 
 15  Campath  [12] 19, 20, 49, 51, 60, 62, 65, 164, 234, 283, 285, 326 💬 
 16  Campath, busulfan, clofarabine  Busulfan  [2] D00248, D03546 💬  [3] POLA1, POLA2, RRM1 💬  [6] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism  [1] 326 💬 
 17  Campath-1h  [6] 19, 20, 60, 234, 285, 326 💬 
 18  Cd34+ enriched, t cell depleted donor stem cell product  [1] 326 💬 
 19  Clofarabine  Clofarabine  [1] D03546 💬  [3] POLA1, POLA2, RRM1 💬  [6] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism  [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 
 20  Cyclophosphamide  Cyclophosphamide  [2] D00287, D07760 💬  [44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬 
 21  Cyclophosphamide 30  Cyclophosphamide  [2] D00287, D07760 💬  [3] 65, 285, 326 💬 
 22  Cyclophosphamide 40  Cyclophosphamide  [2] D00287, D07760 💬  [3] 65, 285, 326 💬 
 23  Cyclosporin  Cyclosporine  [1] D00184 💬  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬  [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway  [17] 38, 46, 49, 50, 53, 56, 60, 62, 63, 93, 95, 97, 113, 164, 222, 274, 326 💬 
 24  Cyclosporin, methotrexate (gvhd prophylaxis)  Cyclosporine  [3] D00142, D00184, D02115 💬  [7] DHFR, DHFR2, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬  [37] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Antifolate resistance, Axon guidance, B cell receptor signaling pathway, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Folate biosynthesis, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, One carbon pool by folate, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway  [1] 326 💬 
 25  Device: miltenyi biotec clinimacs  [2] 62, 326 💬 
 26  Fludarabine  Fludarabine  [2] D01907, D07966 💬  [1] RRM1 💬  [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism  [17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 
 27  Fludarabine monophosphate  Fludarabine  [2] D01907, D07966 💬  [1] RRM1 💬  [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism  [3] 65, 284, 326 💬 
 28  Hematopoetic stem cell transplantation  [5] 19, 65, 120, 160, 326 💬 
 29  Imd  [5] 19, 20, 125, 234, 326 💬 
 30  Imd preparative regimen  [5] 19, 20, 125, 234, 326 💬 
 31  Interferon gamma  Interferon Gamma  [8] 18, 65, 85, 107, 228, 299, 301, 326 💬 
 32  Interferon gamma-1b  Interferon Gamma  [1] D00747 💬  [2] IFNGR1, IFNGR2 💬  [18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis  [7] 18, 65, 85, 228, 299, 301, 326 💬 
 33  Methotrexate  Methotrexate  [2] D00142, D02115 💬  [2] DHFR, DHFR2 💬  [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate  [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 
 34  Osteopetrosis haploidentical only preparative regimen  [5] 19, 20, 125, 234, 326 💬 
 35  Osteopetrosis only preparative regimen  [5] 19, 20, 125, 234, 326 💬 
 36  Other: palliative care  [5] 19, 65, 120, 160, 326 💬 
 37  Procedure: marrow graft transplantation  [1] 326 💬 
 38  Procedure: stem cell or umbilical cord blood transplantation  [1] 326 💬 
 39  Procedure: stem cell transplantation  [6] 19, 51, 60, 62, 65, 326 💬 
 40  Procedure: total lymphoid irradiation  [3] 65, 284, 326 💬 
 41  Procedure: umbilical cord blood transplantation  [5] 60, 65, 284, 285, 326 💬 
 42  Radiation: total lymphoid irradiation  [1] 326 💬 
 43  Rhpth  Parathyroid hormone  [1] D05364 💬  [2] PTH1R, PTH2R 💬  [3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action  [3] 70, 235, 326 💬 
 44  Rimiducid  Rimiducid  [1] D11195 💬  [1] CASP9 💬  [34] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway  [6] 19, 60, 65, 284, 285, 326 💬 
 45  Rivogenlecleucel  [6] 19, 60, 65, 284, 285, 326 💬 
 46  Rivogenleucleucel  [3] 60, 285, 326 💬 
 47  Rp-l401  [1] 326 💬 
 48  Stem cell transplantation  [10] 13, 19, 20, 46, 65, 90, 125, 164, 234, 326 💬 
 49  Systemic chemotherapy and antibodies  [2] 62, 326 💬 
 50  Thymoglobulin  Antithymocyte immunoglobulin (rabbit)  [6] 36, 51, 60, 65, 96, 326 💬 

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