Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	5009111000001105	-	-	-	-	[1] 43 💬
2	Alemtuzumab	Alemtuzumab	[1] D02802 💬	-	-	[16] 13, 15, 19, 20, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284 💬
3	Avacopan	Avacopan	[1] D11093 💬	[1] C5AR1 💬	[5] Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection	[4] 43, 44, 222, 223 💬
4	Azathioprine	Azathioprine	[2] D00238, D03033 💬	-	-	[20]  6 , 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 94, 95, 96, 97, 162 💬
5	Belimumab	Belimumab	[1] D03068 💬	[1] TNFSF13B 💬	[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis	[10] 11, 43, 44, 46, 49, 51, 53, 66, 222, 300 💬
6	Belimumab 10 mg/kg	Belimumab	[1] D03068 💬	[1] TNFSF13B 💬	[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis	[3] 43, 46, 49 💬
7	Benlysta	-	-	-	-	[5] 43, 49, 53, 66, 222 💬
8	Benlysta 400 mg powder for concentrate for solution for infusion	-	-	-	-	[2] 43, 49 💬
9	Benlysta 400mg polvere per concentrato per soluzione per infusione	-	-	-	-	[1] 43 💬
10	Blisibimod	Blisibimod	[1] D10311 💬	-	-	[5] 43, 44, 49, 63, 66 💬
11	Ccx168	-	-	-	-	[6] 43, 44, 66, 109, 222, 223 💬
12	Cellcept	-	-	-	-	[5] 11, 13, 42, 43, 49 💬
13	Cellcept (mycophenolate mofetil)	Mycophenolate mofetil	[4] D00752, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[2] 42, 43 💬
14	Chimeric monoclonal antibody, igg4 subtype	-	-	-	-	[2] 43, 44 💬
15	Corticosteroid	-	-	-	-	[10] 13, 42, 43, 44, 45, 66, 84, 96, 97, 222 💬
16	Corticosteroid and azathioprine	Azathioprine	[2] D00238, D03033 💬	-	-	[4] 42, 43, 44, 45 💬
17	Cyclophosphamide	Cyclophosphamide	[2] D00287, D07760 💬	-	-	[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
18	Cyclophosphamide, azathioprine,prednisone,methylprednisolone	Azathioprine	[11] D00238, D00287, D00407, D00473, D00751, D00979, D03033, D05000, D05001, D05002, D07760 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[3] 42, 43, 45 💬
19	Deltacortene	-	-	-	-	[2] 43, 97 💬
20	Endoxan	-	-	-	-	[7] 13, 28, 43, 44, 85, 96, 222 💬
21	Endoxan baxter	-	-	-	-	[3] 13, 43, 96 💬
22	Freeze-dried sulfonated human normal immunoglobulin (ggs)	Human immunoglobulin G	-	-	-	[3] 14, 43, 45 💬
23	Galen® tablet	-	-	-	-	[2] 43, 44 💬
24	Glucocorticoid (gc)	-	-	-	-	[2] 43, 44 💬
25	Glucocorticoids	-	-	-	-	[8] 40, 41, 43, 44, 60, 62, 75, 300 💬
26	Glucocorticoids (gc)	-	-	-	-	[2] 43, 44 💬
27	Glucocorticoids - reduced dose	-	-	-	-	[2] 43, 44 💬
28	Glucocorticoids - standard dose	-	-	-	-	[2] 43, 44 💬
29	Glucocorticoids [reduced dose]	-	-	-	-	[2] 43, 44 💬
30	Glucocorticoids [standard dose]	-	-	-	-	[2] 43, 44 💬
31	Human normal immunoglobulin	Human immunoglobulin G	-	-	-	[9] 11, 13, 14, 43, 45, 50, 51, 63, 65 💬
32	Hydroxychloroquine	Hydroxychloroquine	[1] D08050 💬	-	-	[23] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 66, 84, 89, 90, 96, 218, 222, 234, 254, 271, 298, 299 💬
33	Ifx-1	-	-	-	-	[3] 43, 44, 269 💬
34	Infliximab	Infliximab	[1] D02598 💬	[1] TNF 💬	[65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	[24] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 162, 164, 269, 271 💬
35	Intravenous immunoglobulins (human immunoglobulins g)	-	-	-	-	[1] 43 💬
36	Intravenous methyl prednisolone	Prednisolone	[8] D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 43 💬
37	Mabthera	-	-	-	-	[22] 11, 13, 14, 19, 35, 43, 44, 46, 49, 50, 51, 52, 53, 61, 63, 64, 65, 83, 93, 162, 222, 271 💬
38	Mabthera®	-	-	-	-	[6] 13, 35, 43, 44, 46, 93 💬
39	Mabthera® 100mg	-	-	-	-	[1] 43 💬
40	Mabthera® 500mg	-	-	-	-	[1] 43 💬
41	Methotrexate	Methotrexate	[2] D00142, D02115 💬	[2] DHFR, DHFR2 💬	[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate	[35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
42	Methyl prednisolone	Prednisolone	[8] D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[3] 43, 49, 96 💬
43	Methylprednisolone	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
44	Methylprednisolone (or other glucocorticoid)	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 43 💬
45	Mycophenolate	Mycophenolic acid	[1] D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
46	Mycophenolate mofetil	Mycophenolate mofetil	[4] D00752, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
47	Mycophenolate mofetil,methotrexate	Methotrexate	[6] D00142, D00752, D02115, D05094, D05095, D05096 💬	[4] DHFR, DHFR2, IMPDH1, IMPDH2 💬	[7] Antifolate resistance, Biosynthesis of cofactors, Drug metabolism - other enzymes, Folate biosynthesis, Metabolic pathways, One carbon pool by folate, Purine metabolism	[3] 42, 43, 45 💬
48	Mycophenolic acid	Mycophenolic acid	[1] D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[8] 11, 43, 49, 51, 60, 66, 96, 222 💬
49	Naltrexone	Naltrexone	[2] D02095, D05113 💬	[3] OPRD1, OPRK1, OPRM1 💬	[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	[12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
50	Naltrexone hydrochloride	Naltrexone	[2] D02095, D05113 💬	[3] OPRD1, OPRK1, OPRM1 💬	[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	[8] 10, 40, 41, 42, 43, 44, 45, 96 💬
51	Other: no plasma exchange	-	-	-	-	[2] 43, 44 💬
52	Pednisone	-	-	-	-	[2] 43, 44 💬
53	Placebo (physiological saline)	-	-	-	-	[2] 43, 45 💬
54	Plaquenil - hydroxychloroquine 200mg film coated tablets	Hydroxychloroquine	[1] D08050 💬	-	-	[3] 43, 44, 45 💬
55	Prednisolone	Prednisolone	[8] D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
56	Prednison acis® 20 mg	-	-	-	-	[2] 43, 44 💬
57	Prednison acis® 5 mg	-	-	-	-	[2] 43, 44 💬
58	Prednisone	Prednisone	[1] D00473 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[47]  2 ,  6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
59	Prednisone (and methylprednisolone)	Methylprednisolone	[7] D00407, D00473, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 43 💬
60	Prednisone tablets, usp	Prednisone	[1] D00473 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[3] 41, 43, 44 💬
61	Prednisone, methylprednisolone,cyclophosphamides	Methylprednisolone	[7] D00407, D00473, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[3] 42, 43, 45 💬
62	Procedure: plasma exchange	-	-	-	-	[5] 13, 43, 44, 64, 222 💬
63	Remission induction therapy	-	-	-	-	[2] 43, 44 💬
64	Rituximab	Rituximab	[1] D02994 💬	[1] MS4A1 💬	[1] Hematopoietic cell lineage	[47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
65	Rituximab (arm a)	Rituximab	[1] D02994 💬	[1] MS4A1 💬	[1] Hematopoietic cell lineage	[2] 43, 44 💬
66	Rituximab (arm b)	Rituximab	[1] D02994 💬	[1] MS4A1 💬	[1] Hematopoietic cell lineage	[2] 43, 44 💬
67	Rixathon 500mg	-	-	-	-	[1] 43 💬
68	Ro0452294/v01	-	-	-	-	[2] 43, 44 💬
69	Ro0452294/v02	-	-	-	-	[3] 35, 43, 44 💬
70	Ro106-1443	-	-	-	-	[1] 43 💬
71	Sendoxan	-	-	-	-	[2] 13, 43 💬
72	Tocilizumab	Tocilizumab	[1] D02596 💬	[1] IL6R 💬	[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor	[18]  2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
73	Vitamin d	Vitamin D	-	-	-	[21] 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 274, 298, 299 💬

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