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36 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  Anti-thymocyte globulin  [18] 11, 13, 14, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 164, 283, 284, 285 💬 
 2  Azathioprine  Azathioprine  [2] D00238, D03033 💬  [20]  6 , 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 94, 95, 96, 97, 162 💬 
 3  Benralizumab  Benralizumab  [1] D09874 💬  [1] IL5RA 💬  [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer  [4] 44, 45, 98, 162 💬 
 4  Corticosteroid  [10] 13, 42, 43, 44, 45, 66, 84, 96, 97, 222 💬 
 5  Corticosteroid and azathioprine  Azathioprine  [2] D00238, D03033 💬  [4] 42, 43, 44, 45 💬 
 6  Cyclophosphamide  Cyclophosphamide  [2] D00287, D07760 💬  [44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬 
 7  Cyclophosphamide, azathioprine,prednisone,methylprednisolone  Azathioprine  [11] D00238, D00287, D00407, D00473, D00751, D00979, D03033, D05000, D05001, D05002, D07760 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [3] 42, 43, 45 💬 
 8  Cyclosporine  Cyclosporine  [1] D00184 💬  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬  [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway  [35] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 62, 63, 64, 65, 90, 95, 97, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302 💬 
 9  Filgrastim  Filgrastim  [1] D03235 💬  [1] CSF3R 💬  [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer  [27]  2 ,  6 , 13, 25, 26, 28, 34, 35, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 
 10  Freeze-dried sulfonated human normal immunoglobulin (ggs)  Human immunoglobulin G  [3] 14, 43, 45 💬 
 11  Hpc cell infusion  [1] 45 💬 
 12  Human normal immunoglobulin  Human immunoglobulin G  [9] 11, 13, 14, 43, 45, 50, 51, 63, 65 💬 
 13  Hydroxychloroquine  Hydroxychloroquine  [1] D08050 💬  [23] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 66, 84, 89, 90, 96, 218, 222, 234, 254, 271, 298, 299 💬 
 14  Infliximab  Infliximab  [1] D02598 💬  [1] TNF 💬  [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [24] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 162, 164, 269, 271 💬 
 15  L04ac06  [2] 44, 45 💬 
 16  Medi-563  [3] 44, 45, 98 💬 
 17  Mepolizumab  Mepolizumab  [1] D04923 💬  [1] IL5 💬  [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation  [4] 44, 45, 98, 162 💬 
 18  Mesna  [11] 11, 13, 44, 45, 49, 51, 60, 65, 85, 96, 164 💬 
 19  Methotrexate  Methotrexate  [2] D00142, D02115 💬  [2] DHFR, DHFR2 💬  [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate  [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 
 20  Methylprednisolone  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 
 21  Mycophenolate  Mycophenolic acid  [1] D05096 💬  [2] IMPDH1, IMPDH2 💬  [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism  [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 
 22  Mycophenolate mofetil  Mycophenolate mofetil  [4] D00752, D05094, D05095, D05096 💬  [2] IMPDH1, IMPDH2 💬  [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism  [32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 
 23  Mycophenolate mofetil,methotrexate  Methotrexate  [6] D00142, D00752, D02115, D05094, D05095, D05096 💬  [4] DHFR, DHFR2, IMPDH1, IMPDH2 💬  [7] Antifolate resistance, Biosynthesis of cofactors, Drug metabolism - other enzymes, Folate biosynthesis, Metabolic pathways, One carbon pool by folate, Purine metabolism  [3] 42, 43, 45 💬 
 24  Naltrexone  Naltrexone  [2] D02095, D05113 💬  [3] OPRD1, OPRK1, OPRM1 💬  [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway  [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬 
 25  Naltrexone hydrochloride  Naltrexone  [2] D02095, D05113 💬  [3] OPRD1, OPRK1, OPRM1 💬  [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway  [8] 10, 40, 41, 42, 43, 44, 45, 96 💬 
 26  Nucala  [2] 44, 45 💬 
 27  Nucala 100 mg powder for solution for injection  [2] 44, 45 💬 
 28  Placebo (physiological saline)  [2] 43, 45 💬 
 29  Plaquenil - hydroxychloroquine 200mg film coated tablets  Hydroxychloroquine  [1] D08050 💬  [3] 43, 44, 45 💬 
 30  Prednisolone  Prednisolone  [8] D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 
 31  Prednisone  Prednisone  [1] D00473 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [47]  2 ,  6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 
 32  Prednisone, methylprednisolone,cyclophosphamides  Methylprednisolone  [7] D00407, D00473, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [3] 42, 43, 45 💬 
 33  Procedure: autologous peripheral blood stem cell transplantation  [8] 28, 40, 41, 42, 45, 46, 49, 283 💬 
 34  Rituximab  Rituximab  [1] D02994 💬  [1] MS4A1 💬  [1] Hematopoietic cell lineage  [47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 
 35  Sb-240563  [3] 44, 45, 98 💬 
 36  Sb-240563 (mepolizumab)  Mepolizumab  [1] D04923 💬  [1] IL5 💬  [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation  [2] 44, 45 💬 

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