Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Acetate	Acetate	-	-	-	[43]  1 ,  2 ,  6 , 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299 💬
2	Alx-0081	-	-	-	-	[1] 64 💬
3	Anfibatide	Anfibatide	-	-	-	[1] 64 💬
4	Anti-von willebrand factor nanobody	Von Willebrand Factor Human	-	-	-	[1] 64 💬
5	Anti-von willebrand factor nanobody, caplacizumab	Caplacizumab	[1] D11160 💬	[1] VWF 💬	[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation	[1] 64 💬
6	Anti-von willebrand factor nanobody, inn = caplacizumab	Caplacizumab	[1] D11160 💬	[1] VWF 💬	[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation	[1] 64 💬
7	Apadamtase alfa	Apadamtase alfa	-	-	-	[1] 64 💬
8	Apademtase alfa	-	-	-	-	[1] 64 💬
9	Arc 1779	-	-	-	-	[2] 64, 288 💬
10	Arc1779	-	-	-	-	[2] 64, 288 💬
11	Arc1779 injection	-	-	-	-	[2] 64, 288 💬
12	Bax930	-	-	-	-	[1] 64 💬
13	Bax930 - recombinant human adamts13	-	-	-	-	[1] 64 💬
14	Bax930 or shp655	-	-	-	-	[1] 64 💬
15	Cablivi	-	-	-	-	[1] 64 💬
16	Caplacizumab	Caplacizumab	[1] D11160 💬	[1] VWF 💬	[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation	[1] 64 💬
17	Caplacizumab (alx-0081)	Caplacizumab	[1] D11160 💬	[1] VWF 💬	[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation	[1] 64 💬
18	Caplacizumab (an anti-von willebrand factor nanobody alx-0081)	Caplacizumab	[1] D11160 💬	[1] VWF 💬	[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation	[1] 64 💬
19	Caplacizumab (an anti-von willebrand factor nanobody)	Caplacizumab	[1] D11160 💬	[1] VWF 💬	[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation	[1] 64 💬
20	Corticosteroid treatment (methylprednisolone or prednisolone)	Methylprednisolone	[14] D00407, D00472, D00751, D00979, D00980, D00981, D00982, D01239, D01998, D02156, D03301, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 64 💬
21	Corticosteroids	-	-	-	-	[10] 41, 46, 49, 64, 97, 107, 164, 220, 296, 300 💬
22	Cryosupernatant plasma	-	-	-	-	[1] 64 💬
23	Cyclosporine	Cyclosporine	[1] D00184 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	[32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	[35] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 62, 63, 64, 65, 90, 95, 97, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302 💬
24	Danazol	Danazol	[1] D00289 💬	[3] AR, ESR1, PGR 💬	[11] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway	[5] 60, 63, 64, 65, 285 💬
25	Desmopressin	Desmopressin	[2] D00291, D02235 💬	[2] AVPR2, F8 💬	[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption	[5]  6 , 64, 72, 225, 288 💬
26	Desmopressin acetate	Acetate	[2] D00291, D02235 💬	[2] AVPR2, F8 💬	[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption	[2] 64, 288 💬
27	Dexamethasone	Dexamethasone	[9] D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
28	Hmed-ides	Imlifidase	[1] D11470 💬	-	-	[2] 64, 221 💬
29	Idec-c2b8, ro 45-2294	-	-	-	-	[1] 64 💬
30	Ides	Imlifidase	[1] D11470 💬	-	-	[2] 64, 221 💬
31	Ides (0.25 mg/kg)	Imlifidase	[1] D11470 💬	-	-	[1] 64 💬
32	Ides (0.50 mg/kg)	Imlifidase	[1] D11470 💬	-	-	[1] 64 💬
33	Immunosuppressive treatment (eg, rituximab)	Rituximab	[1] D02994 💬	[1] MS4A1 💬	[1] Hematopoietic cell lineage	[1] 64 💬
34	Mabthera	-	-	-	-	[22] 11, 13, 14, 19, 35, 43, 44, 46, 49, 50, 51, 52, 53, 61, 63, 64, 65, 83, 93, 162, 222, 271 💬
35	Magnesium	Magnesium	-	-	-	[16]  6 , 11, 13, 46, 64, 70, 93, 97, 166, 225, 235, 284, 291, 296, 297, 298 💬
36	Masp-2 antibody	Narsoplimab	[1] D11531 💬	[1] MASP2 💬	[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection	[2] 64, 109 💬
37	Methylprednisolone	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
38	Minirin	-	-	-	-	[2] 64, 288 💬
39	Octaplas	-	-	-	-	[1] 64 💬
40	Octaplas infusion	-	-	-	-	[1] 64 💬
41	Octaplas sd	-	-	-	-	[1] 64 💬
42	Octaplaslg®	-	-	-	-	[1] 64 💬
43	Octaplas®lg	-	-	-	-	[1] 64 💬
44	Octostim	-	-	-	-	[2] 64, 288 💬
45	Oms721	-	-	-	-	[3] 64, 66, 109 💬
46	Oms721 100 mg/ml injection solution, oms00620646, oms620646, masp-2 antibody	Narsoplimab	[1] D11531 💬	[1] MASP2 💬	[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection	[2] 64, 109 💬
47	Oms721 185 mg/ml injection solution, oms00620646, oms620646, masp-2 antibody	Narsoplimab	[1] D11531 💬	[1] MASP2 💬	[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection	[2] 64, 109 💬
48	Other: standard of care	-	-	-	-	[7] 13, 49, 64, 85, 96, 245, 246 💬
49	Plasma exchange (pe)	-	-	-	-	[1] 64 💬
50	Pooled plasma (human), solvent/detergent treated	-	-	-	-	[1] 64 💬
51	Prednisolone	Prednisolone	[8] D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
52	Prednisone	Prednisone	[1] D00473 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[47]  2 ,  6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
53	Procedure: plasma exchange	-	-	-	-	[5] 13, 43, 44, 64, 222 💬
54	Radamts-13	-	-	-	-	[1] 64 💬
55	Recombinant a disintegrin and metalloproteinase thrombospondin type-1 motifs 13	-	-	-	-	[1] 64 💬
56	Recombinant a disintegrin and metalloproteinase with thrombospondin type-1	-	-	-	-	[1] 64 💬
57	Recombinant a disintegrin and metalloproteinase with thrombospondin type-1 motifs	-	-	-	-	[1] 64 💬
58	Recombinant a disintegrin and metalloproteinase with thrombospondin type-1 motifs 13	-	-	-	-	[1] 64 💬
59	Recombinant a disintegrin and metalloproteinase with thrombospondin type-1 motifs 13 (radamts13)	-	-	-	-	[1] 64 💬
60	Recombinant adamts13	-	-	-	-	[1] 64 💬
61	Rituximab	Rituximab	[1] D02994 💬	[1] MS4A1 💬	[1] Hematopoietic cell lineage	[47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
62	Romiplostim	Romiplostim	[1] D08990 💬	[1] MPL 💬	[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway	[4] 60, 63, 64, 65 💬
63	Shp 655 (bax 930)	-	-	-	-	[1] 64 💬
64	Shp655	-	-	-	-	[1] 64 💬
65	Standard of care	-	-	-	-	[12]  6 , 13, 14, 46, 49, 51, 63, 64, 79, 85, 158, 271 💬
66	Standard plasma	-	-	-	-	[1] 64 💬
67	Standrd of care treatment	-	-	-	-	[1] 64 💬
68	Sulfate	Sulfate ion	-	-	-	[25]  2 ,  6 , 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 222, 226, 265, 296, 297, 299 💬
69	Sulfate, magnesium	Magnesium	-	-	-	[1] 64 💬
70	Tak-755 orbax930 or shp655	-	-	-	-	[1] 64 💬
71	Uniplas	-	-	-	-	[1] 64 💬
72	Von willebrand factor	Von Willebrand Factor Human	-	-	-	[2] 64, 288 💬

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