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e.g. Sirolimus, Adalimumab

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188 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  0.5% marcaine  -  -  -  -  [1] 70 💬 
 2  0.9% saline  -  -  -  -  [1] 70 💬 
 3  0002-8971  -  -  -  -  [1] 70 💬 
 4  1mg/kg/hr txa intravenous infusion till the last suture  -  -  -  -  [1] 70 💬 
 5  Acetaminophen  Acetaminophen  [1] D00217 💬  [2] PTGS1, PTGS2 💬  [23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [14] 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 
 6  Acetate  Acetate  -  -  -  [43]  1 ,  2 ,  6 , 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299 💬 
 7  Adjunctive analgesics  -  -  -  -  [1] 70 💬 
 8  Adjunctive anti-depressants  -  -  -  -  [1] 70 💬 
 9  Ak1320 ms  -  -  -  -  [1] 70 💬 
 10  Allogen-li  -  -  -  -  [1] 70 💬 
 11  Alprostadil  Alprostadil  [2] D00180, D02705 💬  [1] PTGER1 💬  [4] Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer  [2] 51, 70 💬 
 12  Amino acids  Amino acids  -  -  -  [3] 70, 240, 298 💬 
 13  Aminocaproic acid  Aminocaproic acid  [1] D00160 💬  [1] PLG 💬  [4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection  [1] 70 💬 
 14  Amniotic fluid allograft  -  -  -  -  [1] 70 💬 
 15  Apple  Apple  -  -  -  [1] 70 💬 
 16  Bilateral transforaminal epidural steroid injections  -  -  -  -  [1] 70 💬 
 17  Bone marrow concentrate  -  -  -  -  [1] 70 💬 
 18  Botulinum toxin type a  Botulinum toxin type A  [1] D00783 💬  [1] SNAP25 💬  [2] Insulin secretion, Synaptic vesicle cycle  [10]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 70, 113, 149 💬 
 19  Botulinum toxin type a (nabota®) injection into the gastrocnemius muscle  Botulinum toxin type A  [1] D00783 💬  [1] SNAP25 💬  [2] Insulin secretion, Synaptic vesicle cycle  [1] 70 💬 
 20  Bupivacaine  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 
 21  Bupivacaïne hcl 0,125% / sufentanil 50 µg flacon à 50 ml  Sufentanil  [2] D00845, D05938 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 70 💬 
 22  Buprenorphine  Buprenorphine  [2] D00836, D07132 💬  [2] OPRK1, OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [2] 46, 70 💬 
 23  Caudal epidural injection  -  -  -  -  [1] 70 💬 
 24  Caudal epidural injection with celestone  -  -  -  -  [1] 70 💬 
 25  Caudal epidural injection with depomedrol  -  -  -  -  [1] 70 💬 
 26  Caudal epidural injection with generic celestone  -  -  -  -  [1] 70 💬 
 27  Celebrex 200mg capsule  -  -  -  -  [1] 70 💬 
 28  Celecoxib  Celecoxib  [1] D00567 💬  [1] PTGS2 💬  [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [9]  2 ,  3 , 34, 46, 70, 89, 161, 171, 271 💬 
 29  Cilostazol  Cilostazol  [1] D01896 💬  [3] PDE3A, PDE3B, TBXA2R 💬  [14] Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway  [2] 51, 70 💬 
 30  Co  -  -  -  -  [5]  6 , 13, 53, 70, 85 💬 
 31  Combination product: goldic serum  -  -  -  -  [1] 70 💬 
 32  Control group  -  -  -  -  [3]  2 , 46, 70 💬 
 33  Creatinine  Creatinine  [1] D03600 💬  -  -  [4]  2 , 46, 60, 70 💬 
 34  Darvocet  -  -  -  -  [1] 70 💬 
 35  Decadron phosphate, injectable  Phosphate ion  -  -  -  [1] 70 💬 
 36  Deksmedetomidiini  -  -  -  -  [1] 70 💬 
 37  Demineralized bone matrix  -  -  -  -  [1] 70 💬 
 38  Depomedrol  -  -  -  -  [1] 70 💬 
 39  Device: apple watch and app  Apple  -  -  -  [1] 70 💬 
 40  Device: bioactive glass-ceramic spacer  -  -  -  -  [1] 70 💬 
 41  Device: cervical orthosis (co)  -  -  -  -  [1] 70 💬 
 42  Device: interbody cage (peek)  -  -  -  -  [1] 70 💬 
 43  Device: interbody cage (titanium)  Titanium  -  -  -  [1] 70 💬 
 44  Device: mastergraft granules  -  -  -  -  [1] 70 💬 
 45  Device: mild® (minimally invasive lumbar decompression)  -  -  -  -  [1] 70 💬 
 46  Device: mri  -  -  -  -  [3] 70, 85, 278 💬 
 47  Device: no orthosis  -  -  -  -  [1] 70 💬 
 48  Device: philips intelivue mp70 monitor  Methamidophos  -  -  -  [1] 70 💬 
 49  Device: pleth variability index (pvi)  -  -  -  -  [1] 70 💬 
 50  Device: therm-apptm th, thermographic camera  -  -  -  -  [1] 70 💬 
 51  Device: titanium cage  Titanium  -  -  -  [1] 70 💬 
 52  Dexamethasone  Dexamethasone  [9] D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬 
 53  Dexamethasone sodium phosphate  Dexamethasone  [9] D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [3] 65, 70, 96 💬 
 54  Dexdor  -  -  -  -  [4]  2 ,  4 ,  6 , 70 💬 
 55  Dexmedetomidine  Dexmedetomidine  [2] D00514, D01205 💬  [3] ADRA2A, ADRA2B, ADRA2C 💬  [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [12]  2 ,  4 ,  6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬 
 56  Dexmedetomidine group  Dexmedetomidine  [2] D00514, D01205 💬  [3] ADRA2A, ADRA2B, ADRA2C 💬  [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [1] 70 💬 
 57  Dexmedetomidine hydrochloride  Dexmedetomidine  [2] D00514, D01205 💬  [3] ADRA2A, ADRA2B, ADRA2C 💬  [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [1] 70 💬 
 58  Dexmedetomidine with ropivacaine  Dexmedetomidine  [4] D00514, D01205, D04048, D08490 💬  [8] ADRA2A, ADRA2B, ADRA2C, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [5] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Neuroactive ligand-receptor interaction, Taste transduction, cGMP-PKG signaling pathway  [1] 70 💬 
 59  Dextrose  Dextrose, unspecified form  -  -  -  [4] 56, 60, 65, 70 💬 
 60  Diphenhydramine  Diphenhydramine  [6] D00300, D00669, D02419, D03285, D03360, D03854 💬  [1] HRH1 💬  [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction  [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 
 61  Eaca  Aminocaproic acid  [1] D00160 💬  [1] PLG 💬  [4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection  [1] 70 💬 
 62  Epidural injection  -  -  -  -  [1] 70 💬 
 63  Epidural local anesthetic injection  -  -  -  -  [1] 70 💬 
 64  Epidural steroid injection  -  -  -  -  [1] 70 💬 
 65  Epsilon-aminocaproic acid (eaca)  Aminocaproic acid  [1] D00160 💬  [1] PLG 💬  [4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection  [1] 70 💬 
 66  Erector spinae plane block (group e)  -  -  -  -  [1] 70 💬 
 67  Erythropoietin  Erythropoietin  [1] D03231 💬  [1] EPOR 💬  [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer  [9]  2 ,  6 , 13, 18, 22, 47, 70, 95, 96 💬 
 68  Esketamine  Esketamine  [1] D07283 💬  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [3]  2 ,  4 , 70 💬 
 69  Esketamine hydrochloride  Esketamine  [1] D07283 💬  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1] 70 💬 
 70  Fentanyl  Fentanyl  [2] D00320, D01399 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [4] 46, 70, 215, 231 💬 
 71  Forsteo  -  -  -  -  [3] 70, 235, 274 💬 
 72  Forteo  -  -  -  -  [1] 70 💬 
 73  Gabapentin  Gabapentin  [1] D00332 💬  [5] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, SLC6A1 💬  [9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle  [5]  6 , 13, 19, 70, 298 💬 
 74  Heparin  Heparin  [1] D07510 💬  [1] SERPINC1 💬  [1] Complement and coagulation cascades  [11] 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬 
 75  Herbal medicine  -  -  -  -  [1] 70 💬 
 76  Hyaluronic acid  Hyaluronic acid  [1] D08043 💬  -  -  [5] 46, 53, 70, 226, 231 💬 
 77  Hydromorphone  Hydromorphone  [2] D00839, D08047 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 70 💬 
 78  I-factor  -  -  -  -  [1] 70 💬 
 79  Kenalog injectable product  -  -  -  -  [1] 70 💬 
 80  Ketamine  Ketamine  [2] D00711, D08098 💬  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [5] 13, 70, 113, 156, 215 💬 
 81  Ketanest  -  -  -  -  [3]  2 ,  4 , 70 💬 
 82  Ketanest-s  -  -  -  -  [3]  2 ,  4 , 70 💬 
 83  Ketorolac  Ketorolac  [2] D00813, D08104 💬  [2] PTGS1, PTGS2 💬  [23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [2] 70, 226 💬 
 84  Limaprost  Limaprost  [1] D02722 💬  [1] PTGER1 💬  [4] Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer  [1] 70 💬 
 85  Liposomal bupivacaine  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [3] 51, 70, 96 💬 
 86  Lumbar interbody fusion with autograft  -  -  -  -  [1] 70 💬 
 87  Lumbar interbody fusion with neofuse  -  -  -  -  [1] 70 💬 
 88  Magnesium  Magnesium  -  -  -  [16]  6 , 11, 13, 46, 64, 70, 93, 97, 166, 225, 235, 284, 291, 296, 297, 298 💬 
 89  Magnesium with ropivacaine  Magnesium  [2] D04048, D08490 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1] 70 💬 
 90  Midazolam  Midazolam  [3] D00550, D00696, D05028 💬  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬  [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction  [11]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 
 91  Mirogabalin  Mirogabalin  [1] D11203 💬  [2] CACNA2D1, CACNA2D2 💬  [7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway  [1] 70 💬 
 92  Misoprostol  Misoprostol  [1] D00419 💬  [3] PTGER2, PTGER3, PTGER4 💬  [9] Calcium signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Pathways in cancer, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway  [3] 46, 70, 271 💬 
 93  Modal  -  -  -  -  [5]  2 ,  6 , 17, 46, 70 💬 
 94  Modified-thoracolumbar interfascial plane block  -  -  -  -  [1] 70 💬 
 95  Monitor  Methamidophos  -  -  -  [18]  2 , 11, 13, 19, 46, 49, 58, 65, 70, 85, 86, 98, 113, 118, 129, 298, 299, 300 💬 
 96  Morphine  Morphine  [3] D00842, D02271, D08233 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [5] 36, 46, 70, 85, 86 💬 
 97  Morphine pca  Morphine  [3] D00842, D02271, D08233 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 70 💬 
 98  Multi-modal pain management [acetaminophen + gabapentin]  Acetaminophen  [2] D00217, D00332 💬  [7] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, PTGS1, PTGS2, SLC6A1 💬  [31] Adrenergic signaling in cardiomyocytes, Alzheimer disease, Arachidonic acid metabolism, Arrhythmogenic right ventricular cardiomyopathy, C-type lectin receptor signaling pathway, Cardiac muscle contraction, Chemical carcinogenesis, Dilated cardiomyopathy, GABAergic synapse, Human cytomegalovirus infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MAPK signaling pathway, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, Synaptic vesicle cycle, TNF signaling pathway, VEGF signaling pathway  [1] 70 💬 
 99  Multi-modal pain management [fentanyl]  Fentanyl  [2] D00320, D01399 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 70 💬 
 100  Multi-modal pain management [intravenous ketamine]  Ketamine  [2] D00711, D08098 💬  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1] 70 💬 
 101  Multi-modal pain management [valium + gabapentin]  Gabapentin  [1] D00332 💬  [5] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, SLC6A1 💬  [9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle  [1] 70 💬 
 102  Neofuse  -  -  -  -  [1] 70 💬 
 103  Nicardipine  Nicardipine  [2] D00617, D08270 💬  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬  [36] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [2] 70, 86 💬 
 104  Normal saline  -  -  -  -  [16]  6 , 17, 22, 36, 46, 49, 60, 70, 94, 96, 210, 211, 226, 276, 296, 299 💬 
 105  Ns-304  -  -  -  -  [3] 70, 86, 88 💬 
 106  Ns-304 placebo  -  -  -  -  [2] 70, 88 💬 
 107  Nsaids  -  -  -  -  [4] 46, 70, 107, 271 💬 
 108  Nucel  -  -  -  -  [1] 70 💬 
 109  Oksikodoni  -  -  -  -  [1] 70 💬 
 110  Opana  -  -  -  -  [1] 70 💬 
 111  Other: control  -  -  -  -  [8]  6 , 19, 70, 75, 85, 97, 162, 193 💬 
 112  Other: conventional pca mode  -  -  -  -  [1] 70 💬 
 113  Other: epiduroscopy  -  -  -  -  [1] 70 💬 
 114  Other: group exercise: community setting  -  -  -  -  [1] 70 💬 
 115  Other: individualized exercises: clinical setting  -  -  -  -  [1] 70 💬 
 116  Other: joint mobilizations (spine, sacroiliac, hip)  -  -  -  -  [1] 70 💬 
 117  Other: no intervention  -  -  -  -  [1] 70 💬 
 118  Other: optimizing basal infusion (b.i)  -  -  -  -  [1] 70 💬 
 119  Other: other intervention(s)  -  -  -  -  [1] 70 💬 
 120  Other: physical therapy  -  -  -  -  [2]  6 , 70 💬 
 121  Oxanest  -  -  -  -  [1] 70 💬 
 122  Oxycodone  Oxycodone  [3] D03783, D05312, D05462 💬  [3] OPRD1, OPRK1, OPRM1 💬  [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway  [7]  6 , 13, 46, 70, 226, 231, 298 💬 
 123  Oxycodone hydrochloride  Oxycodone  [3] D03783, D05312, D05462 💬  [3] OPRD1, OPRK1, OPRM1 💬  [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway  [4]  6 , 70, 226, 298 💬 
 124  Oxycodone orion  Oxycodone  [3] D03783, D05312, D05462 💬  [3] OPRD1, OPRK1, OPRM1 💬  [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway  [1] 70 💬 
 125  Oxygen  Oxygen  [1] D00003 💬  -  -  [18]  6 , 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 193, 226, 294, 299, 330 💬 
 126  Parathyroid hormone  Parathyroid hormone  [1] D05364 💬  [2] PTH1R, PTH2R 💬  [3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action  [2] 70, 235 💬 
 127  Pca  -  -  -  -  [2] 46, 70 💬 
 128  Phosphate  Phosphate ion  -  -  -  [30]  2 ,  3 , 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 256, 276, 283, 284, 285, 286, 299 💬 
 129  Plf with neofuse  -  -  -  -  [1] 70 💬 
 130  Polydeoxyribonucleotides  -  -  -  -  [2] 51, 70 💬 
 131  Predinose oral  -  -  -  -  [1] 70 💬 
 132  Pregabalin  Pregabalin  [1] D02716 💬  [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬  [7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway  [5] 13, 36, 46, 70, 298 💬 
 133  Pregabalin 75mg  Pregabalin  [1] D02716 💬  [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬  [7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway  [1] 70 💬 
 134  Procedure: acupuncture  -  -  -  -  [2] 46, 70 💬 
 135  Procedure: allograft  -  -  -  -  [1] 70 💬 
 136  Procedure: bee venom pharmacopuncture  -  -  -  -  [1] 70 💬 
 137  Procedure: chuna manipulation  -  -  -  -  [1] 70 💬 
 138  Procedure: chuna manual medicine  -  -  -  -  [1] 70 💬 
 139  Procedure: cupping  -  -  -  -  [1] 70 💬 
 140  Procedure: electroacupuncture  -  -  -  -  [2]  6 , 70 💬 
 141  Procedure: epidural local anesthetic injection  -  -  -  -  [1] 70 💬 
 142  Procedure: epidural steroid (dexamethasone) injection  Dexamethasone  [9] D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 70 💬 
 143  Procedure: epidural steroid injection  -  -  -  -  [1] 70 💬 
 144  Procedure: epidural steroid with local anesthetic injection  -  -  -  -  [1] 70 💬 
 145  Procedure: lumbar epidural injection  -  -  -  -  [1] 70 💬 
 146  Procedure: lumbar interlaminar epidural steroid injection  -  -  -  -  [1] 70 💬 
 147  Procedure: manual therapy  -  -  -  -  [1] 70 💬 
 148  Procedure: mild procedure  -  -  -  -  [1] 70 💬 
 149  Procedure: other intervention(s)  -  -  -  -  [1] 70 💬 
 150  Procedure: percutaneous lumbar decompression  -  -  -  -  [1] 70 💬 
 151  Procedure: pharmacopuncture  -  -  -  -  [1] 70 💬 
 152  Procedure: plf with autograft  -  -  -  -  [1] 70 💬 
 153  Procedure: posterolateral spinal fusion with instrumentation  -  -  -  -  [1] 70 💬 
 154  Prolotherapy solution of 20% dextrose  Dextrose, unspecified form  -  -  -  [1] 70 💬 
 155  Remifentanil  Remifentanil  [2] D01177, D08473 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [2]  6 , 70 💬 
 156  Rhpth  Parathyroid hormone  [1] D05364 💬  [2] PTH1R, PTH2R 💬  [3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action  [3] 70, 235, 326 💬 
 157  Rhpth (1-34)  Parathyroid hormone  [1] D05364 💬  [2] PTH1R, PTH2R 💬  [3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action  [1] 70 💬 
 158  Ropivacaine  Ropivacaine  [2] D04048, D08490 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [3] 36, 46, 70 💬 
 159  Ropivacaine plus normal saline  Ropivacaine  [2] D04048, D08490 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1] 70 💬 
 160  S-ketamine  Esketamine  [3] D00711, D07283, D08098 💬  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1] 70 💬 
 161  S-ketamine & midazolam  Esketamine  [6] D00550, D00696, D00711, D05028, D07283, D08098 💬  [21] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [25] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway  [1] 70 💬 
 162  Selexipag  Selexipag  [1] D09994 💬  [1] PTGIR 💬  [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction  [5] 51, 70, 84, 86, 88 💬 
 163  Standard analgesia use [fentanyl]  Fentanyl  [2] D00320, D01399 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 70 💬 
 164  Standard analgesia use [hydromorphone]  Hydromorphone  [2] D00839, D08047 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 70 💬 
 165  Standard analgesia use [oxygen]  Oxygen  [1] D00003 💬  -  -  [1] 70 💬 
 166  Standard analgesia use [volatile anesthesia]  -  -  -  -  [1] 70 💬 
 167  Steroid injections  -  -  -  -  [1] 70 💬 
 168  Sufentanil  Sufentanil  [2] D00845, D05938 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [2] 70, 280 💬 
 169  Sugar pill  -  -  -  -  [8]  5 ,  6 , 49, 67, 70, 86, 206, 210 💬 
 170  Teicoplanin  Teicoplanin  [1] D02142 💬  -  -  [2] 70, 299 💬 
 171  Teriparatide  Teriparatide  [1] D06078 💬  [1] PTH1R 💬  [3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action  [6] 46, 68, 70, 71, 235, 274 💬 
 172  Teriparatide [rdna origin] contains recombinant human parathyroid hormone (1-34)  Parathyroid hormone  [2] D05364, D06078 💬  [2] PTH1R, PTH2R 💬  [3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action  [1] 70 💬 
 173  Titanium  Titanium  -  -  -  [2] 69, 70 💬 
 174  Tramadol  Tramadol  [2] D01355, D08623 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [5] 46, 70, 78, 226, 271 💬 
 175  Tramadol with ropivacaine  Ropivacaine  [4] D01355, D04048, D08490, D08623 💬  [6] OPRM1, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [6] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction  [1] 70 💬 
 176  Tranexamic acid  Tranexamic acid  [1] D01136 💬  [1] PLG 💬  [4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection  [5] 46, 70, 215, 227, 288 💬 
 177  Tranexamic acid 100 mg/ml  Tranexamic acid  [1] D01136 💬  [1] PLG 💬  [4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection  [1] 70 💬 
 178  Transdermal fentanyl matrix, gabapentin  Fentanyl  [3] D00320, D00332, D01399 💬  [6] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, OPRM1, SLC6A1 💬  [12] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Estrogen signaling pathway, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Synaptic vesicle cycle  [1] 70 💬 
 179  Transforaminal epidural injection  -  -  -  -  [1] 70 💬 
 180  Triamcinolone  Triamcinolone  [5] D00385, D00983, D00984, D00985, D06216 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [8] 35, 46, 56, 70, 90, 96, 226, 298 💬 
 181  Triamcinolone acetonide and normal saline solution  Triamcinolone  [5] D00385, D00983, D00984, D00985, D06216 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 70 💬 
 182  Tylenol  -  -  -  -  [1] 70 💬 
 183  Vancomycin  Vancomycin  [2] D00212, D00926 💬  -  -  [7] 46, 70, 94, 96, 97, 296, 299 💬 
 184  Vivigen cellular bone matrix  -  -  -  -  [1] 70 💬 
 185  With u-vanco (vancomycin hydrochloride)  Vancomycin  [2] D00212, D00926 💬  -  -  [1] 70 💬 
 186  Without u-vanco (vancomycin hydrochloride)  Vancomycin  [2] D00212, D00926 💬  -  -  [1] 70 💬 
 187  Wound topically irrigated with 500mg txa  -  -  -  -  [1] 70 💬 
 188  Xylocaine  -  -  -  -  [1] 70 💬 

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