Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	(4s,5r)-5-[3,5-bis(trifluoromethyl)phenyl]-3-{[4’-	-	-	-	-	[1] 79 💬
2	1,2-dihexadecanoyl-sn-glycero-3-phospho-(1-raac-glycerol)	Glycerin	[1] D00028 💬	-	-	[1] 79 💬
3	Aav directed hldlr gene therapy	-	-	-	-	[1] 79 💬
4	Aav8.tbg.hldlr	-	-	-	-	[1] 79 💬
5	Acetate	Acetate	-	-	-	[43]  1 ,  2 ,  6 , 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299 💬
6	Aegr-733	-	-	-	-	[1] 79 💬
7	Ak102	-	-	-	-	[1] 79 💬
8	Akcea-angptl3-lrx	-	-	-	-	[2] 79, 265 💬
9	Alirocumab	Alirocumab	[1] D10335 💬	[1] PCSK9 💬	[1] Cholesterol metabolism	[1] 79 💬
10	Alirocumab sar236553 (regn727)	Alirocumab	[1] D10335 💬	[1] PCSK9 💬	[1] Cholesterol metabolism	[1] 79 💬
11	Aln-60212	-	-	-	-	[1] 79 💬
12	Aln-pcssc	Inclisiran	[1] D11931 💬	[1] PCSK9 💬	[1] Cholesterol metabolism	[1] 79 💬
13	Amg 145	-	-	-	-	[1] 79 💬
14	Amg145	-	-	-	-	[1] 79 💬
15	Anacetrapib	Anacetrapib	[1] D08855 💬	[1] CETP 💬	[1] Cholesterol metabolism	[1] 79 💬
16	Atorvastatin	Atorvastatin	[3] D00258, D00887, D07474 💬	[1] HMGCR 💬	[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis	[17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
17	Calcium	Calcium	-	-	-	[27]  6 , 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
18	Calcium rosuvastatin	Calcium	[2] D01915, D08492 💬	[1] HMGCR 💬	[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis	[1] 79 💬
19	Cer-001	-	-	-	-	[1] 79 💬
20	Cholestyramine	Cholestyramine	-	-	-	[2] 13, 79 💬
21	Comparator: ezetimibe	Ezetimibe	[1] D01966 💬	[1] NPC1L1 💬	[1] Fat digestion and absorption	[2] 79, 260 💬
22	Crestor	-	-	-	-	[3] 49, 79, 299 💬
23	Crestor film-coated tablet	-	-	-	-	[1] 79 💬
24	Crestor tablets (calcium rosuvastatin) film-coated tablets	Calcium	[2] D01915, D08492 💬	[1] HMGCR 💬	[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis	[1] 79 💬
25	Current lipid-lowering treatment	-	-	-	-	[1] 79 💬
26	Device: dextran sulfate adsorption	Dextran	[1] D00060 💬	-	-	[1] 79 💬
27	Device: heparin-induced extracorporeal ldl precipitation	Heparin	[1] D07510 💬	[1] SERPINC1 💬	[1] Complement and coagulation cascades	[1] 79 💬
28	Dextran	Dextran	[1] D00060 💬	-	-	[5]  2 , 62, 79, 96, 97 💬
29	Dppg	-	-	-	-	[1] 79 💬
30	Evinacumab	Evinacumab	[1] D11753 💬	[1] ANGPTL3 💬	[1] Cholesterol metabolism	[1] 79 💬
31	Evinacumab (regn1500)	Evinacumab	[1] D11753 💬	[1] ANGPTL3 💬	[1] Cholesterol metabolism	[1] 79 💬
32	Evolocumab	Evolocumab	[1] D10557 💬	[1] PCSK9 💬	[1] Cholesterol metabolism	[2] 79, 222 💬
33	Evolocumab (amg 145)	Evolocumab	[1] D10557 💬	[1] PCSK9 💬	[1] Cholesterol metabolism	[1] 79 💬
34	Ezetimibe	Ezetimibe	[1] D01966 💬	[1] NPC1L1 💬	[1] Fat digestion and absorption	[4] 49, 79, 93, 260 💬
35	Fenofibrate	Fenofibrate	[1] D00565 💬	[1] PPARA 💬	[8] Adipocytokine signaling pathway, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway	[5]  8 , 79, 93, 94, 265 💬
36	Fluvastatin	Fluvastatin	[2] D00892, D07983 💬	[1] HMGCR 💬	[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis	[3] 79, 218, 222 💬
37	Gemcabene	Gemcabene	-	-	-	[2] 79, 265 💬
38	Glycerol	Glycerin	[1] D00028 💬	-	-	[5]  6 , 13, 79, 316, 317 💬
39	Heparin	Heparin	[1] D07510 💬	[1] SERPINC1 💬	[1] Complement and coagulation cascades	[11] 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬
40	Ibi306	-	-	-	-	[1] 79 💬
41	Implitapide	Implitapide	-	-	-	[1] 79 💬
42	Inclisiran	Inclisiran	[1] D11931 💬	[1] PCSK9 💬	[1] Cholesterol metabolism	[1] 79 💬
43	Inclisiran for injection	Inclisiran	[1] D11931 💬	[1] PCSK9 💬	[1] Cholesterol metabolism	[1] 79 💬
44	Inclisiran sodium	Inclisiran	[1] D11931 💬	[1] PCSK9 💬	[1] Cholesterol metabolism	[1] 79 💬
45	Isis 301012	-	-	-	-	[1] 79 💬
46	Isis 301012 phosphorothioate oligonucleotide	-	-	-	-	[1] 79 💬
47	Isis 703802	-	-	-	-	[1] 79 💬
48	Js002	-	-	-	-	[1] 79 💬
49	Kjx839	-	-	-	-	[1] 79 💬
50	Lapaquistat	Lapaquistat	-	-	-	[1] 79 💬
51	Lapaquistat acetate and current lipid-lowering treatment	Acetate	-	-	-	[1] 79 💬
52	Lib003	-	-	-	-	[1] 79 💬
53	Lojuxta	-	-	-	-	[1] 79 💬
54	Lojuxta 10 mg hard capsules	-	-	-	-	[1] 79 💬
55	Lojuxta 20 mg hard capsules	-	-	-	-	[1] 79 💬
56	Lojuxta 5 mg hard capsules	-	-	-	-	[1] 79 💬
57	Lomitapide	Lomitapide	[1] D09637 💬	[1] MTTP 💬	[1] Fat digestion and absorption	[1] 79 💬
58	Lomitapide 2mg hard capsules	Lomitapide	[1] D09637 💬	[1] MTTP 💬	[1] Fat digestion and absorption	[1] 79 💬
59	Lovastatin	Lovastatin	[1] D00359 💬	[1] HMGCR 💬	[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis	[11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
60	Mbx-8025	MBX-8025	-	-	-	[3] 79, 93, 94 💬
61	Mbx-8025 50 mg (dose escalation period 1)	MBX-8025	-	-	-	[1] 79 💬
62	Mbx-8025 50 mg or 100 mg (dose escalation period 2)	MBX-8025	-	-	-	[1] 79 💬
63	Mbx-8025 50 mg, 100 mg or 200 mg (dose escalation period 3)	MBX-8025	-	-	-	[1] 79 💬
64	Mipomersen	Mipomersen	[1] D08946 💬	-	-	[1] 79 💬
65	Mk-0859	-	-	-	-	[1] 79 💬
66	Nicotinic acid	Niacin	[1] D00049 💬	-	-	[1] 79 💬
67	Omega-3	Omega-3 fatty acids	-	-	-	[7] 13, 46, 49, 66, 79, 96, 299 💬
68	Omega-3 fatty acids	Omega-3 fatty acids	-	-	-	[2] 13, 79 💬
69	Phospholipids	Omega-3 fatty acids	-	-	-	[1] 79 💬
70	Placebo	-	-	-	-	[26]  3 ,  5 ,  6 , 13, 14, 37, 40, 46, 49, 50, 51, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276 💬
71	Praluent	-	-	-	-	[1] 79 💬
72	Pravastatin	Pravastatin	[2] D00893, D08410 💬	[1] HMGCR 💬	[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis	[9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
73	Recombinant human apolipoprotein	-	-	-	-	[1] 79 💬
74	Recombinant human apolipoprotein a-i	-	-	-	-	[1] 79 💬
75	Recombinant human apolipoprotein a-i/phospholipids complex	Omega-3 fatty acids	-	-	-	[1] 79 💬
76	Recombinant human apolipoprotein a1	-	-	-	-	[1] 79 💬
77	Regn1500	-	-	-	-	[1] 79 💬
78	Regn1500 250 mg sc/15 mg/kg iv/450 mg sc	-	-	-	-	[1] 79 💬
79	Repatha	-	-	-	-	[1] 79 💬
80	Repatha (evolocumab)	Evolocumab	[1] D10557 💬	[1] PCSK9 💬	[1] Cholesterol metabolism	[1] 79 💬
81	Repatha 140 mg solution for injection in pre-filled pen	-	-	-	-	[1] 79 💬
82	Repatha 420 mg solution for injection in cartridge	-	-	-	-	[1] 79 💬
83	Rosuvastatin	Rosuvastatin	[2] D01915, D08492 💬	[1] HMGCR 💬	[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis	[11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
84	Rosuvastatin 20mg	Rosuvastatin	[2] D01915, D08492 💬	[1] HMGCR 💬	[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis	[1] 79 💬
85	Rosuvastatin calcium	Calcium	[2] D01915, D08492 💬	[1] HMGCR 💬	[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis	[4] 49, 79, 97, 299 💬
86	Sar236553	-	-	-	-	[1] 79 💬
87	Sfingomielina	-	-	-	-	[1] 79 💬
88	Shr-1209	-	-	-	-	[1] 79 💬
89	Simvastatin	Simvastatin	[1] D00434 💬	[1] HMGCR 💬	[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis	[21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
90	Single intravenous (iv) dose of human low density lipoprotein receptor (ldlr) gene therapy	-	-	-	-	[1] 79 💬
91	Sphingomyelin	-	-	-	-	[1] 79 💬
92	Standard of care	-	-	-	-	[12]  6 , 13, 14, 46, 49, 51, 63, 64, 79, 85, 158, 271 💬
93	Statins	-	-	-	-	[2] 46, 79 💬
94	Sulfate	Sulfate ion	-	-	-	[25]  2 ,  6 , 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 222, 226, 265, 296, 297, 299 💬
95	Tak-475	TAK-475	-	-	-	[1] 79 💬
96	Zd4522	-	-	-	-	[1] 79 💬

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