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99 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  11c-acetate  Acetate  -  -  -  [3] 13, 86, 88 💬 
 2  [18f]fluoro-2-deoxy-2-d-glucose  D-glucose  [1] D00009 💬  -  -  [2] 86, 88 💬 
 3  Acetate  Acetate  -  -  -  [43]  1 ,  2 ,  6 , 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299 💬 
 4  Act-064992  -  -  -  -  [5] 51, 85, 86, 88, 210 💬 
 5  Act-293987  -  -  -  -  [3] 51, 86, 88 💬 
 6  Adempas  -  -  -  -  [5] 51, 86, 88, 225, 299 💬 
 7  Adempas (riociguat, bay63-2521)  Riociguat  [1] D09572 💬  [3] GUCY1A1, GUCY1A2, GUCY1B1 💬  [11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [2] 86, 88 💬 
 8  Adempas®  -  -  -  -  [2] 86, 88 💬 
 9  Ambrisentan  Ambrisentan  [1] D07077 💬  [1] EDNRA 💬  [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [7] 51, 84, 85, 86, 88, 210, 211 💬 
 10  Ambrisentan 5 mg  Ambrisentan  [1] D07077 💬  [1] EDNRA 💬  [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 88 💬 
 11  Ammonia  Ammonia  [1] D02916 💬  -  -  [4]  6 , 17, 86, 88 💬 
 12  Atorvastatin  Atorvastatin  [3] D00258, D00887, D07474 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 
 13  Barnascan  -  -  -  -  [1] 88 💬 
 14  Bay 63-2521  -  -  -  -  [2] 86, 88 💬 
 15  Bay 63-2521 coated tablets 0.5 mg  -  -  -  -  [2] 86, 88 💬 
 16  Bay 63-2521 coated tablets 1 mg  -  -  -  -  [2] 86, 88 💬 
 17  Bay 63-2521 coated tablets 1.5 mg  -  -  -  -  [2] 86, 88 💬 
 18  Bay 63-2521 coated tablets 2 mg  -  -  -  -  [2] 86, 88 💬 
 19  Bay 63-2521 coated tablets 2.5 mg  -  -  -  -  [2] 86, 88 💬 
 20  Bay 63-2521 ir coated tablet 1.0 mg  -  -  -  -  [1] 88 💬 
 21  Bay 63-2521 ir coated tablet 1.5 mg  -  -  -  -  [1] 88 💬 
 22  Bay 63-2521 ir coated tablet 2.0 mg  -  -  -  -  [1] 88 💬 
 23  Bay 63-2521 ir coated tablet 2.5 mg  -  -  -  -  [1] 88 💬 
 24  Bay 63-2521 ir tablet 0.5 mg  -  -  -  -  [1] 88 💬 
 25  Bay 63-2521 ir tablet 1.0 mg  -  -  -  -  [1] 88 💬 
 26  Bay 63-2521 ir tablet 1.5 mg  -  -  -  -  [1] 88 💬 
 27  Bay 63-2521 ir tablet 2.0 mg  -  -  -  -  [1] 88 💬 
 28  Bay 63-2521 ir tablet 2.5 mg  -  -  -  -  [1] 88 💬 
 29  Bay 63-2521 tablets 0.5 mg  -  -  -  -  [2] 86, 88 💬 
 30  Bay 63-2521 tablets 1 mg  -  -  -  -  [2] 86, 88 💬 
 31  Bay 63-2521 tablets 1.5 mg  -  -  -  -  [2] 86, 88 💬 
 32  Bay 63-2521 tablets 2 mg  -  -  -  -  [2] 86, 88 💬 
 33  Bay 63-2521 tablets 2.5 mg  -  -  -  -  [2] 86, 88 💬 
 34  Bay1237592  -  -  -  -  [2] 86, 88 💬 
 35  Behavioral: respiratory and exercise therapy  -  -  -  -  [1] 88 💬 
 36  Behavioral: respiratory and exercise therapy with supplemental oxygen  Oxygen  [1] D00003 💬  -  -  [1] 88 💬 
 37  Bosentan  Bosentan  [2] D01227, D07538 💬  [2] EDNRA, EDNRB 💬  [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 
 38  Bosentan monohydrate  Bosentan  [2] D01227, D07538 💬  [2] EDNRA, EDNRB 💬  [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [4] 51, 84, 86, 88 💬 
 39  Bpa  -  -  -  -  [1] 88 💬 
 40  Cysteine  Cysteine  [2] D00026, D02326 💬  -  -  [11]  6 , 13, 19, 34, 84, 85, 88, 90, 254, 296, 310 💬 
 41  D-glucose  D-glucose  [1] D00009 💬  -  -  [3] 49, 86, 88 💬 
 42  Diagnostic test: endogenous thrombin potential  Thrombin  [1] D00090 💬  -  -  [2] 86, 88 💬 
 43  Diagnostic test: light transmission aggregometry  -  -  -  -  [2] 86, 88 💬 
 44  Diagnostic test: platelet function analyzer-100  -  -  -  -  [2] 86, 88 💬 
 45  Diagnostic test: rotational thromboelastometry  -  -  -  -  [2] 86, 88 💬 
 46  Edoxaban  Edoxaban  [2] D09546, D09710 💬  [1] F10 💬  [1] Complement and coagulation cascades  [2] 46, 88 💬 
 47  Fludeoxyglucose  Fludeoxyglucose  [1] D01843 💬  -  -  [4] 34, 84, 85, 88 💬 
 48  Glucose  Dextrose, unspecified form  -  -  -  [15]  2 ,  6 , 13, 49, 50, 65, 75, 86, 88, 96, 160, 195, 254, 257, 299 💬 
 49  Gsk1325760  -  -  -  -  [2] 86, 88 💬 
 50  Imatinib  Imatinib  [2] D01441, D08066 💬  [3] ABL1, KIT, PDGFRA 💬  [31] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis  [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 
 51  Imatinib mesilate  Imatinib  [2] D01441, D08066 💬  [3] ABL1, KIT, PDGFRA 💬  [31] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis  [3] 13, 86, 88 💬 
 52  Iodine  Iodine  [1] D00108 💬  -  -  [2] 46, 88 💬 
 53  Jnj-67896062 / act-064992  -  -  -  -  [2] 86, 88 💬 
 54  Macitentan  Macitentan  [1] D10135 💬  [2] EDNRA, EDNRB 💬  [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [5] 51, 85, 86, 88, 210 💬 
 55  Macitentan 10 mg  Macitentan  [1] D10135 💬  [2] EDNRA, EDNRB 💬  [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [3] 51, 86, 88 💬 
 56  Macitentan tablets  Macitentan  [1] D10135 💬  [2] EDNRA, EDNRB 💬  [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [2] 86, 88 💬 
 57  Methyl 4,6-diamino-2-[1-(2-fluorobenzyl)-1h-pyrazolo [3,4-b]pyridine-3-yl]-5-pyrimidinyl(methyl)carb  -  -  -  -  [2] 86, 88 💬 
 58  Methyl [4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1h-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]meth  -  -  -  -  [2] 86, 88 💬 
 59  Multihance  -  -  -  -  [2] 86, 88 💬 
 60  N-acetyl cysteine  Cysteine  [2] D00026, D02326 💬  -  -  [7] 13, 19, 34, 85, 88, 296, 310 💬 
 61  Ns-304  -  -  -  -  [3] 70, 86, 88 💬 
 62  Ns-304 placebo  -  -  -  -  [2] 70, 88 💬 
 63  Opsumit  -  -  -  -  [3] 86, 88, 210 💬 
 64  Opsumit®  -  -  -  -  [3] 86, 88, 210 💬 
 65  Oxygen  Oxygen  [1] D00003 💬  -  -  [18]  6 , 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 193, 226, 294, 299, 330 💬 
 66  Oxygen, liquid  Oxygen  [1] D00003 💬  -  -  [2] 86, 88 💬 
 67  Ph-combination therapy  -  -  -  -  [2] 86, 88 💬 
 68  Ph-monotherapy  -  -  -  -  [2] 86, 88 💬 
 69  Placebo  -  -  -  -  [26]  3 ,  5 ,  6 , 13, 14, 37, 40, 46, 49, 50, 51, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276 💬 
 70  Procedure: ballon pulmonary angioplasty  -  -  -  -  [1] 88 💬 
 71  Procedure: balloon pulmonary angioplasty (bpa)  -  -  -  -  [1] 88 💬 
 72  Procedure: long term oxygen therapy  Oxygen  [1] D00003 💬  -  -  [1] 88 💬 
 73  Procedure: no gas  -  -  -  -  [2] 86, 88 💬 
 74  Procedure: pulmonary endarterectomy  -  -  -  -  [1] 88 💬 
 75  Procedure: pulmonary endarteriectomy  -  -  -  -  [1] 88 💬 
 76  Procedure: supplemental oxygen via a mask  Oxygen  [1] D00003 💬  -  -  [1] 88 💬 
 77  Radiation: cardiac pet imaging using f-18-fdg, n-13 ammonia( nh3)  Ammonia  [1] D02916 💬  -  -  [1] 88 💬 
 78  Radiation: computed tomography lung subtraction iodine mapping  Iodine  [1] D00108 💬  -  -  [1] 88 💬 
 79  Remodulin  -  -  -  -  [2] 86, 88 💬 
 80  Remodulin (r)  -  -  -  -  [1] 88 💬 
 81  Remodulin 10mg/ml 20ml  -  -  -  -  [1] 88 💬 
 82  Remodulin 1mg/ml 20ml  -  -  -  -  [1] 88 💬 
 83  Remodulin 2.5mg/ml 20ml  -  -  -  -  [1] 88 💬 
 84  Remodulin 5mg/ml 20ml  -  -  -  -  [1] 88 💬 
 85  Riociguat  Riociguat  [1] D09572 💬  [3] GUCY1A1, GUCY1A2, GUCY1B1 💬  [11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [6] 51, 84, 86, 88, 225, 299 💬 
 86  Riociguat (adempas, bay63-2521)  Riociguat  [1] D09572 💬  [3] GUCY1A1, GUCY1A2, GUCY1B1 💬  [11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [4] 51, 86, 88, 299 💬 
 87  Riociguat oral tablet  Riociguat  [1] D09572 💬  [3] GUCY1A1, GUCY1A2, GUCY1B1 💬  [11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [1] 88 💬 
 88  Ro 47-0203  -  -  -  -  [4] 51, 85, 86, 88 💬 
 89  Sauerstoff  -  -  -  -  [2] 86, 88 💬 
 90  Selexipag  Selexipag  [1] D09994 💬  [1] PTGIR 💬  [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction  [5] 51, 70, 84, 86, 88 💬 
 91  Thrombin  Thrombin  [1] D00090 💬  -  -  [2] 86, 88 💬 
 92  Tracleer  -  -  -  -  [8] 13, 51, 84, 85, 86, 88, 210, 211 💬 
 93  Tracleer 125mg 56cpr riv.  -  -  -  -  [1] 88 💬 
 94  Tracleer*56cpr riv 125mg  -  -  -  -  [3] 51, 86, 88 💬 
 95  Treprostinil  Treprostinil  [1] D06213 💬  [1] PTGIR 💬  [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction  [6] 51, 84, 85, 86, 88, 210 💬 
 96  Treprostinil sodium  Treprostinil  [1] D06213 💬  [1] PTGIR 💬  [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction  [3] 51, 86, 88 💬 
 97  Uptravi  -  -  -  -  [3] 84, 86, 88 💬 
 98  Volibris  -  -  -  -  [4] 51, 85, 86, 88 💬 
 99  Warfarin  Warfarin  [3] D00564, D01280, D08682 💬  [2] NQO1, VKORC1 💬  [6] Biosynthesis of cofactors, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis  [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 

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