Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	(pyr1)apelin-13	-	-	-	-	[1] 86 💬
2	1-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride	Piperazine	[6] D00807, D01393, D02127, D02145, D05486, D06224 💬	-	-	[1] 58 💬
3	10 milligram (mg) fampridine-sr (4-aminopyridine, 4-ap)	Dalfampridine	[1] D04127 💬	[4] KCNA4, KCNC3, KCND2, KCND3 💬	[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia	[1] 13 💬
4	100 mg ap1189	-	-	-	-	[1] 222 💬
5	15 mg fampridine-sr (4-aminopyridine, 4-ap)	Dalfampridine	[1] D04127 💬	[4] KCNA4, KCNC3, KCND2, KCND3 💬	[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia	[1] 13 💬
6	1500mg mesalazine pellets	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
7	20 mg fampridine-sr (4-aminopyridine, 4-ap)	Dalfampridine	[1] D04127 💬	[4] KCNA4, KCNC3, KCND2, KCND3 💬	[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia	[1] 13 💬
8	20 mg sildenafil citrate by mouth	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 86 💬
9	250mg mesalazine pellets	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
10	4-ap	Dalfampridine	[1] D04127 💬	[4] KCNA4, KCNC3, KCND2, KCND3 💬	[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia	[1] 13 💬
11	5% sildenafil cream	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 50 💬
12	50 mg ap1189	-	-	-	-	[1] 46 💬
13	500mg mesalazine pellets	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
14	6abeta - apomorphine-10,11-diol hydrochloride hemihydrate	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
15	6aß - apomorphine-10,11-diol hydrochloride hemihydrate	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
16	750mg mesalazine pellets	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
17	90 mg hydrocortisone acetate suppository with sephure suppository applicator	Acetate	[2] D00088, D00165 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 97 💬
18	[allo-apz2-eb]	-	-	-	-	[1] 36 💬
19	Access program - sildenafil citrate, viagra, revatio	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 86 💬
20	Adsvf application in the right hand	-	-	-	-	[1] 51 💬
21	Allo-apz2-eb	-	-	-	-	[1] 36 💬
22	Any other approved antiepileptic drug	-	-	-	-	[1] 144 💬
23	Aodg (apigenin-7-o-glucuronide)	Apigenin	-	-	-	[1] 97 💬
24	Ap	-	-	-	-	[4]  2 ,  6 , 13, 299 💬
25	Ap-101	-	-	-	-	[1]  2  💬
26	Ap-cd/ld	-	-	-	-	[1]  6  💬
27	Ap-pa02	-	-	-	-	[1] 299 💬
28	Ap09004	-	-	-	-	[1]  6  💬
29	Ap1189	-	-	-	-	[2] 46, 222 💬
30	Ap1903	-	-	-	-	[3] 60, 285, 326 💬
31	Ap1903 a594	-	-	-	-	[3] 60, 285, 326 💬
32	Apabetalone	Apabetalone	[1] D11131 💬	-	-	[1] 86 💬
33	Apadamtase alfa	Apadamtase alfa	-	-	-	[1] 64 💬
34	Apademtase alfa	-	-	-	-	[1] 64 💬
35	Apcc, apcc + txa	-	-	-	-	[1] 288 💬
36	Apd334	-	-	-	-	[4] 93, 96, 97, 269 💬
37	Apd371	-	-	-	-	[1] 96 💬
38	Apd421	-	-	-	-	[1] 107 💬
39	Apd811	-	-	-	-	[1] 86 💬
40	Apelin	-	-	-	-	[1] 86 💬
41	Api	-	-	-	-	[2] 231, 299 💬
42	Api-aat	-	-	-	-	[1] 231 💬
43	Api-aat, ad00370, arc-aat, api drug substance	-	-	-	-	[1] 231 💬
44	Apigenin	Apigenin	-	-	-	[1] 97 💬
45	Apitox - pure honeybee toxin	-	-	-	-	[1] 13 💬
46	Apixaban	Apixaban	[1] D03213 💬	[1] F10 💬	[1] Complement and coagulation cascades	[3] 96, 97, 222 💬
47	Apixaban 2.5 milligram	Apixaban	[1] D03213 💬	[1] F10 💬	[1] Complement and coagulation cascades	[2] 96, 97 💬
48	Apixaban 5 mg	Apixaban	[1] D03213 💬	[1] F10 💬	[1] Complement and coagulation cascades	[1] 222 💬
49	Apl-130277	-	-	-	-	[1]  6  💬
50	Apl-2	-	-	-	-	[5] 61, 62, 66, 222, 223 💬
51	Apla12	-	-	-	-	[1] 46 💬
52	Aplindore	Aplindore	-	-	-	[1]  6  💬
53	Aplindore mr tablets	Aplindore	-	-	-	[1]  6  💬
54	Apn01	Recombinant Human Angiotensin-Converting Enzyme 2	-	-	-	[1] 86 💬
55	Apo-go	-	-	-	-	[1]  6  💬
56	Apo-go®	-	-	-	-	[1]  6  💬
57	Apo-p001	-	-	-	-	[1]  2  💬
58	Apokinon	-	-	-	-	[1]  6  💬
59	Apokyn	-	-	-	-	[1]  6  💬
60	Apomor	-	-	-	-	[1]  6  💬
61	Apomorp	-	-	-	-	[1]  6  💬
62	Apomorphine	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
63	Apomorphine 0.25% (2.5mg/ml)	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
64	Apomorphine hcl injection	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
65	Apomorphine hydrochloride	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
66	Apomorphine hydrochloride 1.8mg inhalation powder, pre-dispensed	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
67	Apomorphine hydrochloride 2.8mg inhalation powder, pre-dispensed	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
68	Apomorphine hydrochloride 4.0 mg inhalation powder, pre-dispensed	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
69	Apomorphine hydrochloride 5.8 mg inhalation powder, pre-dispensed	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
70	Apomorphine hydrochloride hemihydrate	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
71	Apomorphine hydrocloride	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
72	Apomorphine hydrocloride hemihydrate	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
73	Apomorphine infusion	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
74	Apomorphine nasal powder	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
75	Aporon	-	-	-	-	[1]  6  💬
76	Apple	Apple	-	-	-	[1] 70 💬
77	Application of adalimumab	Adalimumab	[1] D02597 💬	[1] TNF 💬	[65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	[1] 96 💬
78	Apply veregen ® 10 % on a randomized area and the moisturizing cream of the other side	-	-	-	-	[1] 160 💬
79	Apratastat	Apratastat	[1] D08859 💬	[2] ADAM17, MMP13 💬	[7] Alzheimer disease, Coronavirus disease - COVID-19, Epithelial cell signaling in Helicobacter pylori infection, IL-17 signaling pathway, Notch signaling pathway, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway	[1] 46 💬
80	Apremilast	Apremilast	[1] D08860 💬	[4] PDE4A, PDE4B, PDE4C, PDE4D 💬	[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway	[6] 46, 50, 56, 97, 162, 271 💬
81	Apremilast (cc-10004)	Apremilast	[1] D08860 💬	[4] PDE4A, PDE4B, PDE4C, PDE4D 💬	[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway	[1] 56 💬
82	Apremilast 20 mg	Apremilast	[1] D08860 💬	[4] PDE4A, PDE4B, PDE4C, PDE4D 💬	[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway	[1] 46 💬
83	Apremilast 30 mg	Apremilast	[1] D08860 💬	[4] PDE4A, PDE4B, PDE4C, PDE4D 💬	[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway	[1] 46 💬
84	Apremilast 30mg	Apremilast	[1] D08860 💬	[4] PDE4A, PDE4B, PDE4C, PDE4D 💬	[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway	[1] 50 💬
85	Apremilast tablet 20 mg	Apremilast	[1] D08860 💬	[4] PDE4A, PDE4B, PDE4C, PDE4D 💬	[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway	[1] 271 💬
86	Apremilast tablet 30 mg bid	Apremilast	[1] D08860 💬	[4] PDE4A, PDE4B, PDE4C, PDE4D 💬	[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway	[1] 271 💬
87	Aprinox	-	-	-	-	[1] 67 💬
88	Apriso 0.375g er cap	-	-	-	-	[1] 97 💬
89	Apriso 375 mg extended-release capsules	-	-	-	-	[1] 97 💬
90	Aproart	-	-	-	-	[1] 65 💬
91	Aprotinin	Aprotinin	[1] D02971 💬	-	-	[1] 28 💬
92	Aprovel	-	-	-	-	[1] 167 💬
93	Aprovel (150 mg)	-	-	-	-	[1] 222 💬
94	Aprovel 150 mg tablets	-	-	-	-	[1] 222 💬
95	Apt-1011	-	-	-	-	[1] 98 💬
96	Apt-1011 - 3 mg	-	-	-	-	[1] 98 💬
97	Apvo210	-	-	-	-	[1] 97 💬
98	Autologous apoptotic cells injection	-	-	-	-	[1] 46 💬
99	Azathioprine or mesalazine	Azathioprine	[3] D00238, D00377, D03033 💬	-	-	[1] 96 💬
100	Bosentan and sildenafil	Bosentan	[4] D01227, D02229, D07538, D08514 💬	[3] EDNRA, EDNRB, PDE5A 💬	[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬
101	Bpr277 ointment (controlled application)	-	-	-	-	[1] 160 💬
102	Brimonidine tartrate posterior segment drug delivery system (brimo ps dds) applicator system	Brimonidine	[2] D02076, D07540 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬	[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway	[1] 90 💬
103	Bupropion	Bupropion	[3] D00817, D07591, D07938 💬	[2] SLC6A2, SLC6A3 💬	[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle	[5]  8 , 18, 21, 96, 171 💬
104	Bupropion & citalopram	Bupropion	[5] D00817, D00822, D07591, D07704, D07938 💬	[3] SLC6A2, SLC6A3, SLC6A4 💬	[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse, Synaptic vesicle cycle	[1] 18 💬
105	Bupropion hydrochloride	Bupropion	[3] D00817, D07591, D07938 💬	[2] SLC6A2, SLC6A3 💬	[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle	[1] 171 💬
106	Canakinumab (who approval pending)	Canakinumab	[1] D09315 💬	[1] IL1B 💬	[42] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection	[1] 106 💬
107	Captopril	Captopril	[1] D00251 💬	[1] ACE 💬	[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system	[2] 17, 86 💬
108	Cbd - oral solution, is known as epidiolex, and is the approved name in the usa.	-	-	-	-	[3] 140, 144, 158 💬
109	Cbd - oral solution, is known as epidyolex, and is the approved name	-	-	-	-	[1] 156 💬
110	Cbd oral solution, is known as epidyolex and is the approved name in the eu	-	-	-	-	[1] 156 💬
111	Cbd-oral solution, is known as epidiolex, and is the approved name in the usa.	-	-	-	-	[1] 158 💬
112	Combination product: twice daily 90 mg hydrocortisone acetate suppository administered with sephure applicator	Acetate	[2] D00088, D00165 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 97 💬
113	Continuous apomorphine infusion	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
114	Corticosteroids (aprednislon)	-	-	-	-	[1] 63 💬
115	Cr002 liquid api	CR002	-	-	-	[1] 299 💬
116	D-methylphenidate	Methylphenidate	[2] D01296, D04999 💬	[2] SLC6A2, SLC6A3 💬	[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle	[1] 84 💬
117	D.3.2 product code where applicable13:	-	-	-	-	[1] 193 💬
118	Delayed and extended release mesalazine	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
119	Device: apple watch and app	Apple	-	-	-	[1] 70 💬
120	Device: endopath from itamar medical - fda approved device.	-	-	-	-	[1] 96 💬
121	Device: novel allergen-specific immune signature directed approach to dietary elimination therapy	-	-	-	-	[1] 98 💬
122	Device: therm-apptm th, thermographic camera	-	-	-	-	[1] 70 💬
123	Dopaminergic agonist + apomorphine	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
124	Duo-therapy with sildenafil + bosentan	Bosentan	[4] D01227, D02229, D07538, D08514 💬	[3] EDNRA, EDNRB, PDE5A 💬	[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬
125	Epidyolex and is the approved name in the eu	-	-	-	-	[1] 156 💬
126	Era and pde-5i (sildenafil, tadalafil, bosentan, macitentan)	Bosentan	[6] D01227, D02008, D02229, D07538, D08514, D10135 💬	[3] EDNRA, EDNRB, PDE5A 💬	[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬
127	Eu-approved roactemra	-	-	-	-	[1] 46 💬
128	Eur-1008 (apt-1008)	-	-	-	-	[1] 299 💬
129	Eur-1008 (apt-1008) high dose	-	-	-	-	[1] 298 💬
130	Eur-1008 (apt-1008) low dose	-	-	-	-	[1] 298 💬
131	Firategrast (usan approved name)	Firategrast	[1] D06590 💬	[1] ITGA4 💬	[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection	[1] 13 💬
132	G04be03- sildenafil - sildenafil (citrato)	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 86 💬
133	Group 3: ustekinumab approximately 6 mg/kg	Ustekinumab	[1] D09214 💬	[3] IL12A, IL12B, IL23A 💬	[26] African trypanosomiasis, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus	[1] 96 💬
134	Hydralazine	Hydralazine	[2] D01302, D08044 💬	[1] AOC3 💬	[5] Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, beta-Alanine metabolism	[1] 67 💬
135	Hydrokortison apl kapsel 2,5 mg	-	-	-	-	[1] 83 💬
136	Injection of apomorphine	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
137	Interferon beta-1a (current approved manufacturing process invloving fbs)	Human interferon beta	[1] D04554 💬	[2] IFNAR1, IFNAR2 💬	[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway	[1] 13 💬
138	Investigators choice of approved aed	-	-	-	-	[1] 144 💬
139	Investigators choice of approved aeds	-	-	-	-	[1] 144 💬
140	Irbesartan approved in the netherlands	Irbesartan	[1] D00523 💬	[1] AGTR1 💬	[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway	[1] 66 💬
141	Irbesartan tablets (approved in the usa. reference listed drug avapro) ndc # 43547-0374-03	Irbesartan	[1] D00523 💬	[1] AGTR1 💬	[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway	[2] 66, 222 💬
142	Irbesartan tablets (ndc# 0955-1041-90 approved in the usa)	Irbesartan	[1] D00523 💬	[1] AGTR1 💬	[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway	[1] 66 💬
143	Irbesartan tablets (ndc# 43547-0374-03 and ndc 43547-374-09, approved in the usa) generic tablets distributed by solco healthcare us, llc	Irbesartan	[1] D00523 💬	[1] AGTR1 💬	[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway	[1] 222 💬
144	Irbesartan tablets (ndc# 43547-375-50 approved in the usa) generic tablets distributed by solco healthcare us, llc	Irbesartan	[1] D00523 💬	[1] AGTR1 💬	[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway	[1] 66 💬
145	Iv apomorphine	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
146	Kamada-api	-	-	-	-	[1] 231 💬
147	Lithium apogepha	-	-	-	-	[1]  2  💬
148	Locally approved intravenous contrast medium for contrast enhanced mri	-	-	-	-	[1] 13 💬
149	Lorcaserin	Lorcaserin	[1] D06613 💬	-	-	[1] 140 💬
150	Mesalazine	Mesalazine	[1] D00377 💬	-	-	[3] 46, 96, 97 💬
151	Mesalazine (3,600 mg)	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
152	Mesalazine (asacol®)	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
153	Mesalazine (mesalamine)	Mesalazine	[1] D00377 💬	-	-	[1] 96 💬
154	Mesalazine - tid 1000 mg	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
155	Mesalazine - tid 2x 500 mg	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
156	Mesalazine 1000 mg gastro-resistant tablets	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
157	Mesalazine 250mg	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
158	Mesalazine 250mg tablet and nitazoxanide 500mg oral tablet	Mesalazine	[2] D00377, D02486 💬	-	-	[1] 97 💬
159	Mesalazine 4g enema	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
160	Mesalazine 500 mg gastro-resistant tablets (salofa	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
161	Mesalazine 500 mg gastro-resistant tablets (salofalk® 500 mg)	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
162	Mesalazine ec 500 mg	Mesalazine	[1] D00377 💬	-	-	[1] 96 💬
163	Mesalazine enema	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
164	Mesalazine liquid enema	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
165	Mesalazine slow-release granules	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
166	Mesalazine sustained-release tablets	Mesalazine	[1] D00377 💬	-	-	[1] 96 💬
167	Mesalazine tablet	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
168	Mesalazine tablets	Mesalazine	[1] D00377 💬	-	-	[1] 96 💬
169	Mesalazine with hydrocortisone sodium succinate	Hydrocortisone	[2] D00088, D00377 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 97 💬
170	Mesalazine, tripterygium glycosides	Mesalazine	[1] D00377 💬	-	-	[1] 96 💬
171	Methylphenidate	Methylphenidate	[2] D01296, D04999 💬	[2] SLC6A2, SLC6A3 💬	[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle	[7]  6 , 13, 34, 84, 113, 179, 206 💬
172	Methylphenidate (mpd)	Methylphenidate	[2] D01296, D04999 💬	[2] SLC6A2, SLC6A3 💬	[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle	[1]  6  💬
173	Methylphenidate (overencapsulated)	Methylphenidate	[2] D01296, D04999 💬	[2] SLC6A2, SLC6A3 💬	[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle	[1] 84 💬
174	Methylphenidate 10mg tablets	Methylphenidate	[2] D01296, D04999 💬	[2] SLC6A2, SLC6A3 💬	[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle	[1] 84 💬
175	Methylphenidate hydrochloride	Methylphenidate	[2] D01296, D04999 💬	[2] SLC6A2, SLC6A3 💬	[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle	[2]  6 , 13 💬
176	Methylphenidate modified release	Methylphenidate	[2] D01296, D04999 💬	[2] SLC6A2, SLC6A3 💬	[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle	[1] 13 💬
177	Methylphenidate modified release 20 mg	Methylphenidate	[2] D01296, D04999 💬	[2] SLC6A2, SLC6A3 💬	[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle	[1] 13 💬
178	Methylphenidate modified release 30 mg	Methylphenidate	[2] D01296, D04999 💬	[2] SLC6A2, SLC6A3 💬	[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle	[1] 13 💬
179	Methylphenidate modified release 40 mg	Methylphenidate	[2] D01296, D04999 💬	[2] SLC6A2, SLC6A3 💬	[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle	[1] 13 💬
180	Methylphenidate, fluoxetin, risperidone	Fluoxetine	[5] D00326, D00426, D00823, D01296, D04999 💬	[5] DRD2, HTR2A, SLC6A2, SLC6A3, SLC6A4 💬	[14] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Serotonergic synapse, Synaptic vesicle cycle, cAMP signaling pathway	[2] 179, 206 💬
181	Mmx mesalamine/ mesalazine	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
182	Mmx mesalamine/mesalazine	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
183	Mmx mesalamine/mesalazine (high dose)	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
184	Mmx mesalamine/mesalazine (low dose)	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
185	Mono-therapy with sildenafil	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 86 💬
186	Non applicabile	-	-	-	-	[1] 51 💬
187	Non applicable	-	-	-	-	[2] 10, 19 💬
188	Oral sildenafil	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 86 💬
189	Other: controls primary cervical dystonia (trihexyphenidyl)	Trihexyphenidyl	[2] D00787, D08638 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬	[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway	[1]  6  💬
190	Other: mesalazine	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
191	Other: parkinson mpower mobile application	-	-	-	-	[1]  6  💬
192	Other: real-time data capture app	Bifenthrin	-	-	-	[1] 46 💬
193	Other: smartphone application	-	-	-	-	[1] 49 💬
194	Other: standard of care sildenafil	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[2] 90, 301 💬
195	Overencapsulated mesalazine tablets	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
196	Patients' existing non-steroidal anti-inflammatory drug (nsaid) at approved doses	-	-	-	-	[1] 46 💬
197	Pegcetacoplan (apl-2)	-	-	-	-	[2]  2 , 62 💬
198	Piperazine	Piperazine	[6] D00807, D01393, D02127, D02145, D05486, D06224 💬	-	-	[1] 58 💬
199	Primary cervical dystonia (trihexyphenidyl)	Trihexyphenidyl	[2] D00787, D08638 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬	[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway	[1]  6  💬
200	Procedure: apheresis	-	-	-	-	[1] 60 💬
201	Procedure: apheresis catheter placement	-	-	-	-	[1] 96 💬
202	Recombinant human angiotensin-converting enzyme 2 (ace2), apn01	Angiotensin II	[2] D00150, D02014 💬	[2] AGTR1, AGTR2 💬	[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway	[1] 86 💬
203	Recombinant human apolipoprotein	-	-	-	-	[1] 79 💬
204	Recombinant human apolipoprotein a-i	-	-	-	-	[1] 79 💬
205	Recombinant human apolipoprotein a-i/phospholipids complex	Omega-3 fatty acids	-	-	-	[1] 79 💬
206	Recombinant human apolipoprotein a1	-	-	-	-	[1] 79 💬
207	Riociguat granules 0.3% for oral application	Riociguat	[1] D09572 💬	[3] GUCY1A1, GUCY1A2, GUCY1B1 💬	[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway	[1] 86 💬
208	S.c. apomorphine	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
209	Sildenafil	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
210	Sildenafil (50 mg)	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 85 💬
211	Sildenafil (acute-1 hour)	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 299 💬
212	Sildenafil (as citrate)	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 86 💬
213	Sildenafil (revatio)	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 86 💬
214	Sildenafil (revatio) 20 mg tid	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 86 💬
215	Sildenafil (subchronic-4 weeks)	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 299 💬
216	Sildenafil 20 mg tablets	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 278 💬
217	Sildenafil 20mg	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[2] 51, 86 💬
218	Sildenafil 20mg and bosentan 62.5mg	Bosentan	[4] D01227, D02229, D07538, D08514 💬	[3] EDNRA, EDNRB, PDE5A 💬	[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[2] 51, 86 💬
219	Sildenafil 40mg oral capsule	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 299 💬
220	Sildenafil and losartan	Losartan	[4] D00357, D02229, D08146, D08514 💬	[2] AGTR1, PDE5A 💬	[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Purine metabolism, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway	[1] 85 💬
221	Sildenafil by injection	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 210 💬
222	Sildenafil citrate	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[4] 51, 85, 86, 225 💬
223	Sildenafil citrate (uk-92,480)	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 86 💬
224	Sildenafil filmtabletten	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 86 💬
225	Sildenafil singly or in association with bosentan	Bosentan	[4] D01227, D02229, D07538, D08514 💬	[3] EDNRA, EDNRB, PDE5A 💬	[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬
226	Sildenafil therapy	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 51 💬
227	Sitaxsentan and sildenafil	Sildenafil	[3] D02229, D07171, D08514 💬	[2] EDNRA, PDE5A 💬	[9] Calcium signaling pathway, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬
228	Sodium tanshinone iia sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth	Dextrose, unspecified form	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 86 💬
229	Spd476 (mesalazine)	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
230	Spd476 is a polymeric matrix formulation that displays both delayed- and extended-release of mesalazine	Mesalazine	[1] D00377 💬	-	-	[1] 97 💬
231	Spironolactone captopril carvedilol	Captopril	[4] D00251, D00255, D00443, D03415 💬	[7] ACE, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, NR3C2 💬	[18] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dilated cardiomyopathy, Gap junction, Hypertrophic cardiomyopathy, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Renin-angiotensin system, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬
232	Subcutaneous apomorphine	Apomorphine	[2] D02004, D07460 💬	[2] DRD1, DRD2 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
233	Tadalafil and sildenafil	Sildenafil	[3] D02008, D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 113 💬
234	Tipranavir	Tipranavir	[2] D03843, D08605 💬	-	-	[1] 265 💬
235	Trifluoperazine	Trifluoperazine	[3] D00799, D01448, D08636 💬	[1] DRD2 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[2] 283, 284 💬
236	Trihexyphenidyl	Trihexyphenidyl	[2] D00787, D08638 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬	[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway	[2]  5 ,  6  💬
237	Ustekinumab (approximately 6 mg/kg)	Ustekinumab	[1] D09214 💬	[3] IL12A, IL12B, IL23A 💬	[26] African trypanosomiasis, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus	[1] 49 💬
238	Ustekinumab approximately 6 mg/kg (iv)	Ustekinumab	[1] D09214 💬	[3] IL12A, IL12B, IL23A 💬	[26] African trypanosomiasis, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus	[1] 96 💬
239	Volanesorsen sodium, apoc-iii antisense oligonucleotide	Volanesorsen	[1] D11648 💬	[1] APOC3 💬	[2] Cholesterol metabolism, PPAR signaling pathway	[1] 265 💬
240	Wellbutrin (bupropion)	Bupropion	[3] D00817, D07591, D07938 💬	[2] SLC6A2, SLC6A3 💬	[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle	[1] 96 💬

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