Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Azathioprine	Azathioprine	[2] D00238, D03033 💬	-	-	[20]  6 , 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 94, 95, 96, 97, 162 💬
2	Azathioprine (aza)	Azathioprine	[2] D00238, D03033 💬	-	-	[3] 13, 19, 97 💬
3	Azathioprine (aza) caps	Azathioprine	[2] D00238, D03033 💬	-	-	[1] 96 💬
4	Azathioprine (aza) or 6-mercaptopurine (6-mp)	Azathioprine	[4] D00161, D00238, D03033, D04931 💬	[1] HPRT1 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[2] 96, 97 💬
5	Azathioprine (imuran) 50 mg overencapsulated tablet	Azathioprine	[2] D00238, D03033 💬	-	-	[1] 97 💬
6	Azathioprine - ratiopharm 50 mg	Azathioprine	[2] D00238, D03033 💬	-	-	[1] 96 💬
7	Azathioprine / 6 mercaptopurine	Azathioprine	[4] D00161, D00238, D03033, D04931 💬	[1] HPRT1 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[1] 96 💬
8	Azathioprine 25 mg	Azathioprine	[2] D00238, D03033 💬	-	-	[1] 44 💬
9	Azathioprine and allopurinol	Allopurinol	[3] D00224, D00238, D03033 💬	[1] XDH 💬	[5] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Peroxisome, Purine metabolism	[1] 97 💬
10	Azathioprine in case of endoscopic recurrence	Azathioprine	[2] D00238, D03033 💬	-	-	[1] 96 💬
11	Azathioprine individualised dose	Azathioprine	[2] D00238, D03033 💬	-	-	[1] 96 💬
12	Azathioprine or 6-mercaptopurine	Azathioprine	[4] D00161, D00238, D03033, D04931 💬	[1] HPRT1 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[2] 96, 97 💬
13	Azathioprine or adalimumab and infliximab	Adalimumab	[4] D00238, D02597, D02598, D03033 💬	[1] TNF 💬	[65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	[1] 96 💬
14	Azathioprine or mesalazine	Azathioprine	[3] D00238, D00377, D03033 💬	-	-	[1] 96 💬
15	Azathioprine or methotrexate	Azathioprine	[4] D00142, D00238, D02115, D03033 💬	[2] DHFR, DHFR2 💬	[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate	[1] 96 💬
16	Azathioprine or mycophenolate mofetil	Azathioprine	[6] D00238, D00752, D03033, D05094, D05095, D05096 💬	[2] IMPDH1, IMPDH2 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[1] 162 💬
17	Azathioprine weight-based dose	Azathioprine	[2] D00238, D03033 💬	-	-	[1] 96 💬
18	Azathioprine+enteral nutrition	Azathioprine	[2] D00238, D03033 💬	-	-	[1] 96 💬
19	Azathioprine/prednisone	Azathioprine	[3] D00238, D00473, D03033 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 85 💬
20	Combination of protein a immunoadsorption, rituximab, dexamethasone plus azathioprine	Azathioprine	[12] D00238, D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592, D02994, D03033 💬	[2] MS4A1, NR3C1 💬	[2] Hematopoietic cell lineage, Neuroactive ligand-receptor interaction	[1] 35 💬
21	Continuation of azathioprine	Azathioprine	[2] D00238, D03033 💬	-	-	[1] 49 💬
22	Corticosteroid and azathioprine	Azathioprine	[2] D00238, D03033 💬	-	-	[4] 42, 43, 44, 45 💬
23	Cyclophosphamide followed by methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids	Azathioprine	[6] D00142, D00238, D00287, D02115, D03033, D07760 💬	[2] DHFR, DHFR2 💬	[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate	[1] 44 💬
24	Cyclophosphamide, azathioprine,prednisone,methylprednisolone	Azathioprine	[11] D00238, D00287, D00407, D00473, D00751, D00979, D03033, D05000, D05001, D05002, D07760 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[3] 42, 43, 45 💬
25	Cyclophosphamide-prednisone-azathioprine	Azathioprine	[5] D00238, D00287, D00473, D03033, D07760 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 49 💬
26	Early immunosuppressants (azathioprine, methotrexate)	Azathioprine	[4] D00142, D00238, D02115, D03033 💬	[2] DHFR, DHFR2 💬	[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate	[1] 96 💬
27	Immunosuppressive regime (azathioprine, mycophenolate mofetil or methotrexate)	Azathioprine	[8] D00142, D00238, D00752, D02115, D03033, D05094, D05095, D05096 💬	[4] DHFR, DHFR2, IMPDH1, IMPDH2 💬	[7] Antifolate resistance, Biosynthesis of cofactors, Drug metabolism - other enzymes, Folate biosynthesis, Metabolic pathways, One carbon pool by folate, Purine metabolism	[1] 49 💬
28	Infliximab and azathioprine combination at week 0	Azathioprine	[3] D00238, D02598, D03033 💬	[1] TNF 💬	[65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	[1] 96 💬
29	Infliximab and azathioprine combination at week 14	Azathioprine	[3] D00238, D02598, D03033 💬	[1] TNF 💬	[65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	[1] 96 💬
30	Infliximab with azathioprine (iifx + aza)	Azathioprine	[3] D00238, D02598, D03033 💬	[1] TNF 💬	[65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	[1] 96 💬
31	Infliximab+azathioprine	Azathioprine	[3] D00238, D02598, D03033 💬	[1] TNF 💬	[65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	[1] 96 💬
32	Infliximab, azathioprine	Azathioprine	[3] D00238, D02598, D03033 💬	[1] TNF 💬	[65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	[1] 96 💬
33	Overencapsulated azathioprine (imuran) 50 mg tablet	Azathioprine	[2] D00238, D03033 💬	-	-	[1] 97 💬
34	Prednisone - azathioprine	Azathioprine	[3] D00238, D00473, D03033 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 11 💬
35	Products containing azathioprine or 6-mercaptopurine	Azathioprine	[4] D00161, D00238, D03033, D04931 💬	[1] HPRT1 💬	[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	[1] 97 💬
36	Rituximab (rtx) and azathioprine (aza)	Azathioprine	[3] D00238, D02994, D03033 💬	[1] MS4A1 💬	[1] Hematopoietic cell lineage	[1] 65 💬
37	Steroids plus azathioprine	Azathioprine	[2] D00238, D03033 💬	-	-	[1] 66 💬
38	Symptomatic treatment, steroids, immunosuppressive agents( azathioprine, tacrolimus, mycophenolate mofetil)	Azathioprine	[8] D00107, D00238, D00752, D03033, D05094, D05095, D05096, D08556 💬	[7] IMPDH1, IMPDH2, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	[35] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Drug metabolism - other enzymes, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Purine metabolism, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	[1] 11 💬

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