Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Busulfan, cyclophosphamide, thymoglobulin, fludarabine (conditioning regimen)	Antithymocyte immunoglobulin (rabbit)	[5] D00248, D00287, D01907, D07760, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[1] 326 💬
2	Busulfan, fludarabine and atg	Busulfan	[3] D00248, D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[1] 65 💬
3	Busulfan, fludarabine, & cyclophosphamide with immunosuppression with atg and cyclosporine.	Busulfan	[6] D00184, D00248, D00287, D01907, D07760, D07966 💬	[6] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, RRM1 💬	[37] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Drug metabolism - other enzymes, Glucagon signaling pathway, Glutamatergic synapse, Glutathione metabolism, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Purine metabolism, Pyrimidine metabolism, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	[2] 60, 285 💬
4	Busulfan, fludarabine, atg, tli	Busulfan	[3] D00248, D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[2] 65, 284 💬
5	Busulfan/fludarabine phosphate/tacrolimus/methotrexate/g-csf	Busulfan	[8] D00107, D00142, D00248, D01907, D02115, D03235, D07966, D08556 💬	[9] CSF3R, DHFR, DHFR2, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, RRM1 💬	[46] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Antifolate resistance, Axon guidance, B cell receptor signaling pathway, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Drug metabolism - other enzymes, Folate biosynthesis, Glucagon signaling pathway, Glutamatergic synapse, Glutathione metabolism, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, One carbon pool by folate, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Purine metabolism, Pyrimidine metabolism, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	[1] 60 💬
6	Campath, fludarabine, cyclophosphamide	Cyclophosphamide	[4] D00287, D01907, D07760, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[2] 65, 284 💬
7	Cyclophosphamide and fludarabine	Cyclophosphamide	[4] D00287, D01907, D07760, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[1] 13 💬
8	Cyclophosphamide, fludarabine	Cyclophosphamide	[4] D00287, D01907, D07760, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[1] 285 💬
9	Cyclophosphamide, fludarabine , thymoglobulin	Antithymocyte immunoglobulin (rabbit)	[4] D00287, D01907, D07760, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[1] 60 💬
10	Cyclophosphamide, fludarabine, rabbit atg	Antithymocyte immunoglobulin (rabbit)	[4] D00287, D01907, D07760, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[1] 60 💬
11	Cyclophosphamide, fludarabine, thymoglobulin	Antithymocyte immunoglobulin (rabbit)	[4] D00287, D01907, D07760, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[1] 60 💬
12	Fludarabine	Fludarabine	[2] D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
13	Fludarabine (flu)	Fludarabine	[2] D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[2] 60, 285 💬
14	Fludarabine monophosphate	Fludarabine	[2] D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[3] 65, 284, 326 💬
15	Fludarabine phosphate	Fludarabine	[2] D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[11] 28, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285 💬
16	Fludarabine phosphate 30 mg	Fludarabine	[2] D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[2] 65, 164 💬
17	Fludarabine phosphate 40 mg	Fludarabine	[2] D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[2] 65, 164 💬
18	Fludarabine, busulfan, thymoglobulin	Antithymocyte immunoglobulin (rabbit)	[3] D00248, D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[1] 65 💬
19	Fludarabine, cyclophosphamide	Cyclophosphamide	[4] D00287, D01907, D07760, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[1] 60 💬
20	Fludarabine, melphalan, thiotepa	Fludarabine	[4] D00369, D00583, D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[1] 65 💬
21	Fludarabine/ melphalan	Fludarabine	[3] D00369, D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[1] 60 💬
22	Fludarabine/busulfan	Busulfan	[3] D00248, D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[1] 60 💬
23	Sq fludarabine	Fludarabine	[2] D01907, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[1] 49 💬
24	Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan	Alemtuzumab	[5] D00369, D00583, D01907, D02802, D07966 💬	[1] RRM1 💬	[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism	[2] 65, 164 💬

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