Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone)	Acetate	[21] D00088, D00292, D00472, D00473, D00973, D00975, D00980, D00981, D00982, D01239, D01510, D01615, D01632, D01948, D01998, D02156, D02174, D02591, D02592, D03301, D07749 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 81 💬
2	Cyclophosphamide followed by methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids	Azathioprine	[6] D00142, D00238, D00287, D02115, D03033, D07760 💬	[2] DHFR, DHFR2 💬	[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate	[1] 44 💬
3	Cyclosporin a+glucocorticoids	Cyclosporine	[1] D00184 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	[32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	[2] 60, 62 💬
4	Glucocorticoid	-	-	-	-	[2] 46, 228 💬
5	Glucocorticoid (gc)	-	-	-	-	[2] 43, 44 💬
6	Glucocorticoid (prednisone or prednisolone)	Prednisolone	[9] D00472, D00473, D00980, D00981, D00982, D01239, D01998, D02156, D03301 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 84 💬
7	Glucocorticoid agent	-	-	-	-	[1] 46 💬
8	Glucocorticoid treatment	-	-	-	-	[1] 41 💬
9	Glucocorticoids	-	-	-	-	[8] 40, 41, 43, 44, 60, 62, 75, 300 💬
10	Glucocorticoids (gc)	-	-	-	-	[2] 43, 44 💬
11	Glucocorticoids (permitted,not necessary)	-	-	-	-	[1] 46 💬
12	Glucocorticoids - reduced dose	-	-	-	-	[2] 43, 44 💬
13	Glucocorticoids - standard dose	-	-	-	-	[2] 43, 44 💬
14	Glucocorticoids [reduced dose]	-	-	-	-	[2] 43, 44 💬
15	Glucocorticoids [standard dose]	-	-	-	-	[2] 43, 44 💬
16	Gusperimus + glucocorticoids	Gusperimus	[1] D08032 💬	-	-	[1] 44 💬
17	Levamisole+cyclosporin a+glucocorticoids	Cyclosporine	[3] D00184, D00750, D08114 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	[32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	[2] 60, 62 💬
18	Methylprednisolone (or other glucocorticoid)	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[1] 43 💬
19	Standard glucocorticoid therapy	-	-	-	-	[1] 81 💬
20	Tocilizumab + glucocorticoids (gcs)	Tocilizumab	[1] D02596 💬	[1] IL6R 💬	[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor	[1] 41 💬
21	Ursodeoxycholic acid+low dose glucocorticoid(prednisone)	Prednisone	[2] D00473, D00734 💬	[2] NR1H4, NR3C1 💬	[2] Bile secretion, Neuroactive ligand-receptor interaction	[1] 93 💬

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