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55 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  Acthar high dose (80 u)  -  -  -  -  [1] 49 💬 
 2  Administration of a high dose of desipramine  Desipramine  [2] D00812, D07791 💬  [2] SLC6A2, SLC6A4 💬  [2] Serotonergic synapse, Synaptic vesicle cycle  [1] 156 💬 
 3  Ambrisentan - high dose  Ambrisentan  [1] D07077 💬  [1] EDNRA 💬  [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 86 💬 
 4  Bi 655064 high dose  -  -  -  -  [1] 46 💬 
 5  Biil 284 bs high dose  -  -  -  -  [1] 46 💬 
 6  Biil 284 bs, high dose  -  -  -  -  [1] 299 💬 
 7  Biil 284 bs, high dose, adult patients  -  -  -  -  [1] 299 💬 
 8  Biil 284 bs, high dose, pediatric patients  -  -  -  -  [1] 299 💬 
 9  Birb 796 bs, high dose  -  -  -  -  [1] 46 💬 
 10  Bli-1300 high dose  -  -  -  -  [1] 96 💬 
 11  Brazikumab high dose  Brazikumab  [1] D10912 💬  [1] IL23A 💬  [9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis  [1] 96 💬 
 12  Clobazam high dose  Clobazam  [1] D01253 💬  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬  [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction  [1] 144 💬 
 13  Cvn424 high dose  -  -  -  -  [1]  6  💬 
 14  Cvt-301 high dose  -  -  -  -  [1]  6  💬 
 15  Dns-7801 (high dose)  -  -  -  -  [1]  6  💬 
 16  Elamipretide (high dose)  Elamipretide  [1] D10925 💬  -  -  [1] 21 💬 
 17  Eur-1008 (apt-1008) high dose  -  -  -  -  [1] 298 💬 
 18  Fentanyl (high dose)  Fentanyl  [2] D00320, D01399 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 215 💬 
 19  High dose  -  -  -  -  [1] 97 💬 
 20  High dose affitope® pd03a + adjuvant  -  -  -  -  [1]  6  💬 
 21  High dose anavex2-73  -  -  -  -  [1]  6  💬 
 22  High dose aspirin (1300 mg/day)  Acetylsalicylic acid  [1] D00109 💬  [2] PTGS1, PTGS2 💬  [23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [1] 13 💬 
 23  High dose bibf 1120 twice daily  -  -  -  -  [1] 85 💬 
 24  High dose budesonide  Budesonide  [1] D00246 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 97 💬 
 25  High dose budesonide suspension  Budesonide  [1] D00246 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 98 💬 
 26  High dose budesonide tablet  Budesonide  [1] D00246 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 98 💬 
 27  High dose dexamethasone pulses  Dexamethasone  [9] D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 63 💬 
 28  High dose lactulose  Lactulose  [1] D00352 💬  -  -  [1] 291 💬 
 29  High dose mesenchymal stem cells (mscs)  -  -  -  -  [1] 49 💬 
 30  High dose of biil 284 bs tablets  -  -  -  -  [1] 46 💬 
 31  High dose of budesonide  Budesonide  [1] D00246 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 299 💬 
 32  High dose ortd-1  -  -  -  -  [1] 46 💬 
 33  High dose tso  -  -  -  -  [1] 96 💬 
 34  High dose vehicle control  -  -  -  -  [1] 46 💬 
 35  High dose-vis649  -  -  -  -  [1] 66 💬 
 36  High doses of thiamine y biotin  Biotin  [2] D00029, D08580 💬  -  -  [1]  8  💬 
 37  Hmpl-004 high dose  -  -  -  -  [1] 97 💬 
 38  Igpro20 (high dose)  -  -  -  -  [1] 14 💬 
 39  Kps-0373, high dose  -  -  -  -  [1] 18 💬 
 40  Kw-6356 high dose  -  -  -  -  [1]  6  💬 
 41  Liris low dose and liris high dose  -  -  -  -  [1] 226 💬 
 42  Lx3305 high dose  -  -  -  -  [1] 46 💬 
 43  Medi7183 high dose  -  -  -  -  [1] 97 💬 
 44  Mmx mesalamine/mesalazine (high dose)  Mesalazine  [1] D00377 💬  -  -  [1] 97 💬 
 45  Mt-1303 high dose  -  -  -  -  [1] 49 💬 
 46  Mt-7117 high dose  -  -  -  -  [1] 254 💬 
 47  Multistem high dose  MultiStem  -  -  -  [1] 97 💬 
 48  Pf-06649751 high dose (15 mg qd)  Tavapadon  [1] D11431 💬  [2] DRD1, DRD5 💬  [10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway  [1]  6  💬 
 49  Procedure: non-myeloablative high dose immunosuppressive therapy conditioning (hdit)  -  -  -  -  [1] 49 💬 
 50  Pxt3003 high dose  -  -  -  -  [1] 10 💬 
 51  Ravicti high dose  -  -  -  -  [1] 299 💬 
 52  Sen0014196 (high dose)  -  -  -  -  [1]  8  💬 
 53  Tas5315 high dose  -  -  -  -  [1] 46 💬 
 54  Vitamin d3 - high dose  Cholecalciferol  [1] D00188 💬  [1] VDR 💬  [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis  [1]  6  💬 
 55  Yra-1909 high dose  -  -  -  -  [1] 46 💬 

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