Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	150-mg ivacaftor	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
2	150mg ivacaftor	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
3	Cf patients with a g551d mutation and treated with ivacaftor	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
4	Deuterated ivacaftor	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
5	Elexacaftor-tezacaftor-ivacaftor exposure	Elexacaftor	[3] D09916, D11041, D11507 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
6	Ivacaftor	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
7	Ivacaftor (proposed inn)	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
8	Ivacaftor 125mg tablet	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
9	Ivacaftor 150 mg	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
10	Ivacaftor 150 mg or 250 mg	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
11	Ivacaftor 25 mg/75 mg	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
12	Ivacaftor 75 mg	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
13	Ivacaftor 75 mg/150 mg	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
14	Ivacaftor exposed	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
15	Ivacaftor or elexacaftor/tezacaftor/ivacaftor	Elexacaftor	[3] D09916, D11041, D11507 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
16	Ivacaftor+lumacaftor	Ivacaftor	[2] D09916, D10134 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
17	Ivacaftor/ataluren	Ataluren	[2] D09323, D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
18	Ivacaftor/kalydeco	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
19	Lumacaftor / ivacaftor	Ivacaftor	[2] D09916, D10134 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
20	Lumacaftor plus ivacaftor	Ivacaftor	[2] D09916, D10134 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
21	Lumacaftor plus ivacaftor combination	Ivacaftor	[2] D09916, D10134 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
22	Lumacaftor, ivacaftor drug combination	Ivacaftor	[2] D09916, D10134 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
23	Lumacaftor-ivacaftor	Ivacaftor	[2] D09916, D10134 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
24	Lumacaftor-ivacaftor treatment	Ivacaftor	[2] D09916, D10134 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
25	Lumacaftor/ivacaftor	Ivacaftor	[2] D09916, D10134 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
26	Lumacaftor/ivacaftor 100mg/125mg tablets	Ivacaftor	[2] D09916, D10134 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
27	Lumacaftor/ivacaftor 200mg/125mg	Ivacaftor	[2] D09916, D10134 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
28	Lumacaftor/ivacaftor 200mg/125mg tablets	Ivacaftor	[2] D09916, D10134 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
29	Lumacaftor/ivacaftor 200mg/83mg tablet	Ivacaftor	[2] D09916, D10134 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
30	Orkambi: contains lumacaftor and ivacaftor	Ivacaftor	[2] D09916, D10134 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
31	Tezacaftor/ivacaftor	Ivacaftor	[2] D09916, D11041 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
32	Tezacaftor/ivacaftor + ivacaftor	Ivacaftor	[2] D09916, D11041 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
33	Tezacaftor/ivacaftor 100mg/150mg	Ivacaftor	[2] D09916, D11041 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
34	Tezacaftor/ivacaftor/100mg/150mg	Ivacaftor	[2] D09916, D11041 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
35	Vx-659/tezacaftor/ivacaftor	Ivacaftor	[2] D09916, D11041 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
36	Vx-661 plus ivacaftor combination	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
37	Vx-661/ivacaftor	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
38	Vx-661/ivacaftor (vx-770) 100mg/150 mg	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
39	Vx-661/ivacaftor 100 mg/ 150 mg	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
40	Vx-661/ivacaftor 100mg/150 mg	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
41	Vx-661/ivacaftor 100mg/150mg	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬
42	Vx-661/ivacaftor 50 mg/ 75 mg	Ivacaftor	[1] D09916 💬	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	[1] 299 💬

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