Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Ambrisentan	Ambrisentan	[1] D07077 💬	[1] EDNRA 💬	[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[7] 51, 84, 85, 86, 88, 210, 211 💬
2	Ambrisentan - high dose	Ambrisentan	[1] D07077 💬	[1] EDNRA 💬	[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬
3	Ambrisentan - low dose	Ambrisentan	[1] D07077 💬	[1] EDNRA 💬	[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬
4	Ambrisentan 5 mg	Ambrisentan	[1] D07077 💬	[1] EDNRA 💬	[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 88 💬
5	Ambrisentan 5 mg film-coated tablets	Ambrisentan	[1] D07077 💬	[1] EDNRA 💬	[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬
6	Ambrisentan 5mg film-coated tablets [marketed product]	Ambrisentan	[1] D07077 💬	[1] EDNRA 💬	[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬
7	Ambrisentan plus spironolactone	Ambrisentan	[2] D00443, D07077 💬	[2] EDNRA, NR3C2 💬	[8] Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬
8	Ambrisentan tablet	Ambrisentan	[1] D07077 💬	[1] EDNRA 💬	[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬
9	Bosentan, ambrisentan	Ambrisentan	[3] D01227, D07077, D07538 💬	[2] EDNRA, EDNRB 💬	[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬
10	Letairis	-	-	-	-	[1] 85 💬
11	Letairis 10 mg	-	-	-	-	[1] 85 💬
12	Letairis 5 mg	-	-	-	-	[1] 85 💬
13	Tadalafil and ambrisentan upfront combination therapy	Ambrisentan	[2] D02008, D07077 💬	[2] EDNRA, PDE5A 💬	[9] Calcium signaling pathway, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[2] 51, 86 💬
14	Volibris® (ambrisentan)	Ambrisentan	[1] D07077 💬	[1] EDNRA 💬	[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 86 💬