Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	1 mg qd to 15 mg qd pf-06649751	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
2	1 mg qd to 7 mg qd pf-06649751 (if de-escalated in parent study)	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
3	15 mg qd de-escalated to 7 mg qd pf-06649751 in parent study remain at 7 mg qd	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
4	15 mg qd pf-06649751	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
5	3 mg qd to 15 mg qd pf-06649751	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
6	3 mg qd to 7 mg qd pf-06649751 (de-escalated in parent study)	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
7	7 mg qd to 15 mg qd pf-06649751	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
8	7 mg qd to 7 mg qd pf-06649751 (de-escalated in parent study)	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
9	Pf-06649751	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
10	Pf-06649751 - 15mg	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
11	Pf-06649751 - 1mg	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
12	Pf-06649751 - 5mg	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
13	Pf-06649751 high dose (15 mg qd)	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
14	Pf-06649751 low dose (1 mg qd)	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
15	Pf-06649751 middle dose 1 (3 mg qd)	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬
16	Pf-06649751 middle dose 2 (7 mg qd)	Tavapadon	[1] D11431 💬	[2] DRD1, DRD5 💬	[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway	[1]  6  💬