Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Bms drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin)	Digoxin	[13] D00298, D00330, D00455, D00529, D00550, D00696, D01207, D01475, D02290, D05028, D05259, D05261, D08229 💬	[25] ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP4A, ATP4B, CYSLTR1, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, PTGS1, PTGS2 💬	[49] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Arachidonic acid metabolism, Bile secretion, C-type lectin receptor signaling pathway, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Chemical carcinogenesis, Collecting duct acid secretion, Endocrine and other factor-regulated calcium reabsorption, GABAergic synapse, Gastric acid secretion, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Insulin secretion, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, Mineral absorption, Morphine addiction, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Nicotine addiction, Ovarian steroidogenesis, Oxidative phosphorylation, Oxytocin signaling pathway, Pancreatic secretion, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, Taste transduction, Thyroid hormone signaling pathway, Thyroid hormone synthesis, VEGF signaling pathway, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 46 💬
2	Dexmedetomidine with ropivacaine	Dexmedetomidine	[4] D00514, D01205, D04048, D08490 💬	[8] ADRA2A, ADRA2B, ADRA2C, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[5] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Neuroactive ligand-receptor interaction, Taste transduction, cGMP-PKG signaling pathway	[1] 70 💬
3	Dopamine agonists (pramipexole, ropirinole)	Dopamine	[4] D00559, D00633, D05575, D07870 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
4	Flurbiprofen	Flurbiprofen	[3] D00330, D01475, D02290 💬	[2] PTGS1, PTGS2 💬	[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	[3] 13, 21, 46 💬
5	Hp-3000 (ropinirole hydrochloride patch)	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
6	Hp-3000(ropinirole hydrochloride patch)	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
7	Magnesium with ropivacaine	Magnesium	[2] D04048, D08490 💬	[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	[1] 70 💬
8	Montelukast, flurbiprofen, midazolam, digoxin, pravastatin and bms-986142	BMS-986142	[11] D00298, D00330, D00529, D00550, D00696, D00893, D01475, D02290, D05028, D08229, D08410 💬	[24] ATP1A1, ATP1A2, ATP1A3, ATP1A4, CYSLTR1, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, HMGCR, PTGS1, PTGS2 💬	[49] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Arachidonic acid metabolism, Bile secretion, C-type lectin receptor signaling pathway, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Chemical carcinogenesis, Endocrine and other factor-regulated calcium reabsorption, GABAergic synapse, Gastric acid secretion, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Insulin secretion, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, Mineral absorption, Morphine addiction, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Nicotine addiction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pancreatic secretion, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, Taste transduction, Terpenoid backbone biosynthesis, Thyroid hormone signaling pathway, Thyroid hormone synthesis, VEGF signaling pathway, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 46 💬
9	Pramipexole or ropinirole	Pramipexole	[4] D00559, D00784, D05575, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
10	Rop	-	-	-	-	[1]  6  💬
11	Rop+l-dopa	Levodopa	[1] D00059 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
12	Ropinirole	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[3]  6 , 74, 309 💬
13	Ropinirole (as hydrochloride)	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
14	Ropinirole controlled-release (requip cr) for rls	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
15	Ropinirole cr 2mg tablet	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
16	Ropinirole cr 8mg tablet	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
17	Ropinirole hydrochloride	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[2]  6 , 309 💬
18	Ropinirole hydrochloride extended-release tablet	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
19	Ropinirole hydrochloride extended-release tablet placebo	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
20	Ropinirole hydrochloride prolonged release	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
21	Ropinirole immediate release	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
22	Ropinirole implant	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
23	Ropinirole ir	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
24	Ropinirole ir tablets	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
25	Ropinirole monotherapy	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
26	Ropinirole oral product	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
27	Ropinirole pr	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
28	Ropinirole pr, 2mg	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
29	Ropinirole pr/xr	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
30	Ropinirole pr/xr tablets	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
31	Ropinirole prolonged release	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
32	Ropinirole prolonged release/extended release(pr/xr)	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
33	Ropinirole xl	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
34	Ropinirole xl (formerly cr)	Ropinirole	[2] D00784, D08489 💬	[3] DRD2, DRD3, DRD4 💬	[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
35	Ropinirole/l-dopa	Levodopa	[3] D00059, D00784, D08489 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬	[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	[1]  6  💬
36	Ropivacaine	Ropivacaine	[2] D04048, D08490 💬	[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	[3] 36, 46, 70 💬
37	Ropivacaine plus normal saline	Ropivacaine	[2] D04048, D08490 💬	[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	[1] 70 💬
38	Tramadol with ropivacaine	Ropivacaine	[4] D01355, D04048, D08490, D08623 💬	[6] OPRM1, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	[6] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction	[1] 70 💬

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