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38 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  Administration of rituximab and methylprednisolone  Methylprednisolone  [7] D00407, D00751, D00979, D02994, D05000, D05001, D05002 💬  [2] MS4A1, NR3C1 💬  [2] Hematopoietic cell lineage, Neuroactive ligand-receptor interaction  [1] 51 💬 
 2  Corticosteroid treatment (methylprednisolone or prednisolone)  Methylprednisolone  [14] D00407, D00472, D00751, D00979, D00980, D00981, D00982, D01239, D01998, D02156, D03301, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 64 💬 
 3  Cyclophosphamide, azathioprine,prednisone,methylprednisolone  Azathioprine  [11] D00238, D00287, D00407, D00473, D00751, D00979, D03033, D05000, D05001, D05002, D07760 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [3] 42, 43, 45 💬 
 4  Infliximab, methylprednisolone, methotrexate  Infliximab  [9] D00142, D00407, D00751, D00979, D02115, D02598, D05000, D05001, D05002 💬  [4] DHFR, DHFR2, NR3C1, TNF 💬  [70] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [1] 46 💬 
 5  Interferon-beta-1a (avonex) plus methylprednisolone  Human interferon beta  [7] D00407, D00751, D00979, D04554, D05000, D05001, D05002 💬  [3] IFNAR1, IFNAR2, NR3C1 💬  [19] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway  [1] 13 💬 
 6  Intravenous (i.v.) methylprednisolone 1000 mg, total 9  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 222 💬 
 7  Intravenous methylprednisolone  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [2] 13, 145 💬 
 8  Iv methylprednisolone  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 13 💬 
 9  Iv methylprednisolone (steroids)  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 13 💬 
 10  Megadose oral methylprednisolone  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 13 💬 
 11  Methotrexate + methylprednisolone  Methotrexate  [8] D00142, D00407, D00751, D00979, D02115, D05000, D05001, D05002 💬  [3] DHFR, DHFR2, NR3C1 💬  [6] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Neuroactive ligand-receptor interaction, One carbon pool by folate  [1] 46 💬 
 12  Methylprednisolon (solu-medrol)  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 14 💬 
 13  Methylprednisolone  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 
 14  Methylprednisolone (drug)  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 13 💬 
 15  Methylprednisolone (mp)  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [2] 60, 285 💬 
 16  Methylprednisolone (mp) or prednisone (pred)  Methylprednisolone  [7] D00407, D00473, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 66 💬 
 17  Methylprednisolone (or other glucocorticoid)  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 43 💬 
 18  Methylprednisolone (solu-medrol)  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 14 💬 
 19  Methylprednisolone 1250 mg/24h x3 days  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 13 💬 
 20  Methylprednisolone acetate  Acetate  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 51 💬 
 21  Methylprednisolone bolus iv 15 mg/kg/d for 3 days.  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 84 💬 
 22  Methylprednisolone hemisuccinate  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 13 💬 
 23  Methylprednisolone iv  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 13 💬 
 24  Methylprednisolone mylan générique  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 66 💬 
 25  Methylprednisolone or budesonide  Budesonide  [7] D00246, D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 96 💬 
 26  Methylprednisolone or prednisolone  Methylprednisolone  [14] D00407, D00472, D00751, D00979, D00980, D00981, D00982, D01239, D01998, D02156, D03301, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 65 💬 
 27  Methylprednisolone po  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 13 💬 
 28  Methylprednisolone pulse  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [2] 66, 220 💬 
 29  Methylprednisolone sodium hemisuccinate  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [2] 13, 97 💬 
 30  Methylprednisolone sodium succinate  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [6] 13, 46, 49, 50, 51, 211 💬 
 31  Methylprednisolone(intravenously in the 1st-2nd-3rd month )  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 66 💬 
 32  Methylprednisolone(intravenously in the 1st-3rd-5th month)  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 66 💬 
 33  Oral 5-asa+/-topical 5-asa+iv corticosteroids / po methylprednisolone  Mesalazine  [7] D00377, D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 97 💬 
 34  Oral methylprednisolone 625 mg/24h x3 days  Methylprednisolone  [6] D00407, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 13 💬 
 35  Prednisone (and methylprednisolone)  Methylprednisolone  [7] D00407, D00473, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 43 💬 
 36  Prednisone, methylprednisolone,cyclophosphamides  Methylprednisolone  [7] D00407, D00473, D00751, D00979, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [3] 42, 43, 45 💬 
 37  Solu-medrol  [7] 13, 49, 50, 51, 53, 97, 211 💬 
 38  Solu-medrol inj. pso lqf 40mg  [1] 50 💬 

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