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147 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  Abatacept active treatment  Abatacept  [1] D03203 💬  [2] CD80, CD86 💬  [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis  [1] 50 💬 
 2  Abatacept delayed-onset treatment  Abatacept  [1] D03203 💬  [2] CD80, CD86 💬  [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis  [1] 50 💬 
 3  Active investigational treatment ent-01  [1]  6  💬 
 4  Active treatment group 7% hypertonic saline  [1] 299 💬 
 5  Baseline treatment  [1] 13 💬 
 6  Bdmard treatment  [1] 271 💬 
 7  Behavioral: co-op treatment protocol  [1]  6  💬 
 8  Behavioral: conservative treatment  [1] 291 💬 
 9  Best medical treatment  [1]  6  💬 
 10  Best médical treatment  [1]  6  💬 
 11  Bisphosphonate treatment  [2] 113, 299 💬 
 12  Botulism toxin treatment  [1] 161 💬 
 13  Break in l-carnitine treatment  Levocarnitine  [3] D02030, D02176, D04713 💬  [1] 316 💬 
 14  Classic dmards treatment group  [1] 46 💬 
 15  Clobetasol propionate cream treatment  Clobetasol  [2] D01272, D07715 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 162 💬 
 16  Combination product: active treatment with dual therapy  [1]  2  💬 
 17  Corticosteroid treatment (methylprednisolone or prednisolone)  Methylprednisolone  [14] D00407, D00472, D00751, D00979, D00980, D00981, D00982, D01239, D01998, D02156, D03301, D05000, D05001, D05002 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 64 💬 
 18  Current lipid-lowering treatment  [1] 79 💬 
 19  Detoxifying agents for antineoplastic treatment  [1] 299 💬 
 20  Dopamine agonist treatment  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1] 74 💬 
 21  Drug treatment  [4] 46, 51, 74, 271 💬 
 22  Era as specific pah treatment  [1] 86 💬 
 23  Etanercept treatment  Etanercept  [1] D00742 💬  [2] LTA, TNF 💬  [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [1] 46 💬 
 24  Experimental (non immunosuppressive symptomatic treatment (nist) and rituximab)  Rituximab  [1] D02994 💬  [1] MS4A1 💬  [1] Hematopoietic cell lineage  [1] 222 💬 
 25  Fibrate treatment  [1] 160 💬 
 26  Foliglurax 10 mg (treatment a)  Foliglurax  [1]  6  💬 
 27  Foliglurax 30 mg (treatment b)  Foliglurax  [1]  6  💬 
 28  From august 2020 'no additional treatment'  [1] 51 💬 
 29  Genotropin (somatropin) is a growth hormone treatment. it is an exact copy of the natural growth hormone that our bodies make. the main difference is that genotropin is man-made.  Somatotropin  [1] D02691 💬  [1] GHR 💬  [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway  [1] 193 💬 
 30  Glucocorticoid treatment  [1] 41 💬 
 31  Golimumab treatment optimization.  Golimumab  [1] D04358 💬  [1] TNF 💬  [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [1] 97 💬 
 32  Hcq/cq and cab combined treatment  [1] 74 💬 
 33  Herbal treatment (sa100)  [1] 97 💬 
 34  Hyperpolarized 129 xenon gas comparing idiopathic pulmonary fibrosis (ipf) treatment  Xenon  [2] D01901, D06339 💬  [1] 85 💬 
 35  Immunosuppressive treatment  [1] 66 💬 
 36  Immunosuppressive treatment (eg, rituximab)  Rituximab  [1] D02994 💬  [1] MS4A1 💬  [1] Hematopoietic cell lineage  [1] 64 💬 
 37  In double-blind phase: treatment with tofacitinib  Tofacitinib  [1] D09970 💬  [4] JAK1, JAK2, JAK3, TYK2 💬  [35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis  [1] 107 💬 
 38  In open-label phase: treatment with tofacitinib  Tofacitinib  [1] D09970 💬  [4] JAK1, JAK2, JAK3, TYK2 💬  [35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis  [1] 107 💬 
 39  Interferon beta treatment to add-on atorvastatin treatment  Atorvastatin  [3] D00258, D00887, D07474 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 13 💬 
 40  Iv treatment with igsc, 10%  [1] 65 💬 
 41  Lapaquistat acetate and current lipid-lowering treatment  Acetate  [1] 79 💬 
 42  Lumacaftor-ivacaftor treatment  Ivacaftor  [2] D09916, D10134 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 43  Metformin treatment  Metformin  [2] D00944, D04966 💬  [2] PRKAA1, PRKAA2 💬  [19] AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway  [1] 46 💬 
 44  Methotrexate treatment  Methotrexate  [2] D00142, D02115 💬  [2] DHFR, DHFR2 💬  [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate  [2] 41, 46 💬 
 45  Mk0812 / duration of treatment: 12 weeks  [1] 46 💬 
 46  Msc treatment  [1] 49 💬 
 47  Msc treatment 01  [1] 96 💬 
 48  Msc treatment 02  [1] 96 💬 
 49  Natalizumab treatment  Natalizumab  [1] D06886 💬  [1] ITGA4 💬  [14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection  [1] 13 💬 
 50  Nifurtimox-eflronithine combination treatment (nect)  Nifurtimox  [1] D00833 💬  [1] 65 💬 
 51  Nusinersen treatments  Nusinersen  [1] D10881 💬  [1] SMN2 💬  [1] RNA transport  [1]  3  💬 
 52  Oc oral solution treatment a  [1]  6  💬 
 53  Oc oral solution treatment b  [1]  6  💬 
 54  Oc oral solution treatment c  [1]  6  💬 
 55  Oc oral solution treatment d  [1]  6  💬 
 56  Only 1 arm: treatment with msc-afp  [1] 96 💬 
 57  Optimized antiparkinsonian treatment  [1]  6  💬 
 58  Oral anticoagulant treatment  [1] 86 💬 
 59  Other parkinson's disease treatments  [1]  6  💬 
 60  Other: adalimumab treatment  Adalimumab  [1] D02597 💬  [1] TNF 💬  [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [1] 151 💬 
 61  Other: best medical treatment  [1]  6  💬 
 62  Other: control wound treatment  [1] 36 💬 
 63  Other: crohn's disease treatment-with-eating diet (cd-treat diet)  [1] 96 💬 
 64  Other: current treatment  [1] 46 💬 
 65  Other: dead sea solar and water treatment  Water  [1] D00001 💬  [1] 46 💬 
 66  Other: diet treatment  [1] 240 💬 
 67  Other: intensify treatment with the existing drug  [2] 96, 97 💬 
 68  Other: motor assessments before taking regular pd treatment  [1]  6  💬 
 69  Other: motor assessments on regular pd treatment  [1]  6  💬 
 70  Other: multidisciplinary intensive rehabilitation treatment  [1]  6  💬 
 71  Other: no active treatment  [1] 274 💬 
 72  Other: no anti-inflammatory treatment  [1] 271 💬 
 73  Other: no it treatment  [1] 19 💬 
 74  Other: no treatment  [2] 53, 256 💬 
 75  Other: no treatment arm  [1] 13 💬 
 76  Other: no treatment given  [1] 78 💬 
 77  Other: observation of ocrelizumab as treatment in rrms patients  Ocrelizumab  [1] D05218 💬  [1] MS4A1 💬  [1] Hematopoietic cell lineage  [1] 13 💬 
 78  Other: on-demand treatment  [1] 299 💬 
 79  Other: other: symptomatic treatment of als  [1]  2  💬 
 80  Other: sle treatment  [1] 49 💬 
 81  Other: standard steroid treatment  [1] 113 💬 
 82  Other: standard treatment  [1] 227 💬 
 83  Other: standard treatment according to the clinical protocols  [1] 49 💬 
 84  Other: usual drug treatment of parkinson's disease  [1]  6  💬 
 85  Plasma from healthy young people treatment + riluzole  Riluzole  [1] D00775 💬  [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway  [1]  2  💬 
 86  Ppi treatment  [1] 299 💬 
 87  Prednisone and ustekinumab treatment  Prednisone  [2] D00473, D09214 💬  [4] IL12A, IL12B, IL23A, NR3C1 💬  [27] African trypanosomiasis, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Malaria, Measles, Neuroactive ligand-receptor interaction, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus  [1] 41 💬 
 88  Prednisone treatment  Prednisone  [1] D00473 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 41 💬 
 89  Probiotic treatment  [1] 294 💬 
 90  Procedure: surgery treatment  [1] 291 💬 
 91  Procedure: transsphenoidal surgery treatment  [1] 74 💬 
 92  Procedure: treatment according to current standards without knowledge of serum infliximab and anti-infliximab ab status  Infliximab  [1] D02598 💬  [1] TNF 💬  [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [1] 96 💬 
 93  Propranolol treatment  Propranolol  [2] D00483, D08443 💬  [3] ADRB1, ADRB2, ADRB3 💬  [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 227 💬 
 94  Regular treatment  [1] 97 💬 
 95  Repository corticotropin injection -treatment extension  Corticotropin  [1] D00146 💬  [1] MC2R 💬  [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 84 💬 
 96  Routine treatment of cd  [1] 96 💬 
 97  Sc treatment with igsc, 10% with rhuph20 followed by iv/igsc, 10% only (safety)  [1] 65 💬 
 98  Sc treatment with igsc, 10% with rhuph20 followed by sc/igsc, 10% only (safety)  [1] 65 💬 
 99  Simvastatin treatment for 28 days  Simvastatin  [1] D00434 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 299 💬 
 100  Standard of care treatment  [2] 245, 246 💬 
 101  Standard steroid treatment  [1] 85 💬 
 102  Standard treatment with a conventional drug  [1] 13 💬 
 103  Standrd of care treatment  [1] 64 💬 
 104  Symptomatic treatment (converting enzyme inhibitor, angiotensin ii, anti-renin, aldosterone antagonist diuretic, beta blocker, calcium inhibitor, statin)  Aldosterone  [3] D00150, D02014, D10528 💬  [3] AGTR1, AGTR2, NR3C2 💬  [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [1] 222 💬 
 105  Symptomatic treatment, steroids, immunosuppressive agents( azathioprine, tacrolimus, mycophenolate mofetil)  Azathioprine  [8] D00107, D00238, D00752, D03033, D05094, D05095, D05096, D08556 💬  [7] IMPDH1, IMPDH2, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬  [35] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Drug metabolism - other enzymes, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Purine metabolism, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway  [1] 11 💬 
 106  Symptomatic treatment, steroids, immunosuppressive agents, plasma exchange(pe), intravenous immunoglobulin(ivig)  Human immunoglobulin G  [1] 11 💬 
 107  Systemic non-biological treatments  [2] 46, 271 💬 
 108  The comprehensive treatment regimen of traditional chinese medicine  [1] 222 💬 
 109  The standard steroid treatment, plasma exchange and rituximab  Rituximab  [1] D02994 💬  [1] MS4A1 💬  [1] Hematopoietic cell lineage  [1] 85 💬 
 110  Time delay treatment of botulinum toxin  [1] 149 💬 
 111  Tl011, anti cd20, for the treatment of rheumatoid arthritis  [1] 46 💬 
 112  Tocilizumab treatment  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 41 💬 
 113  Traditional treatment of cgd and tb  [1] 65 💬 
 114  Traditional treatments  [1] 97 💬 
 115  Treatment  [2] 41, 299 💬 
 116  Treatment a  [2] 34, 46 💬 
 117  Treatment algorithm a  [1] 97 💬 
 118  Treatment algorithm b  [1] 97 💬 
 119  Treatment algorithm c  [1] 97 💬 
 120  Treatment as usual (tau)  [1] 85 💬 
 121  Treatment b  [2] 34, 46 💬 
 122  Treatment bx1514m  [1] 58 💬 
 123  Treatment c  [2] 34, 46 💬 
 124  Treatment d  [1] 34 💬 
 125  Treatment defined only by active substance  [1] 50 💬 
 126  Treatment i  [1] 46 💬 
 127  Treatment ii  [1] 46 💬 
 128  Treatment iii  [1] 46 💬 
 129  Treatment of mtx  [1] 46 💬 
 130  Treatment of mtx and hcq  [1] 46 💬 
 131  Treatment of mtx and twhf  [1] 46 💬 
 132  Treatment of tcm  [1] 46 💬 
 133  Treatment of twhf  [1] 46 💬 
 134  Treatment phase group 4  [1] 113 💬 
 135  Treatment systemic therapy (prednisone)  Prednisone  [1] D00473 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 162 💬 
 136  Treatment with adalimumab  Adalimumab  [1] D02597 💬  [1] TNF 💬  [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [1] 96 💬 
 137  Treatment with azathioprin  [1] 95 💬 
 138  Treatment with mycophenolat mofetil  [1] 95 💬 
 139  Treatment with polyethylene glycol (macrogol 4000)  Polyethylene glycol  [1] D03370 💬  [1] 299 💬 
 140  Treatment with systemic therapy (doxycycline)  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  [1] 162 💬 
 141  Treatment with systemic therapy (methotrexate)  Methotrexate  [2] D00142, D02115 💬  [2] DHFR, DHFR2 💬  [5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate  [1] 162 💬 
 142  Treatment with systemic therapy (prednisone)  Prednisone  [1] D00473 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 162 💬 
 143  Treatment with topical superpotent corticosteroid therapy  [1] 162 💬 
 144  Untreated to atorvastatin treatment  Atorvastatin  [3] D00258, D00887, D07474 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 13 💬 
 145  Usual dopaminergic per os treatment  [1]  6  💬 
 146  Vancomycin pre-treatment  Vancomycin  [2] D00212, D00926 💬  [1] 97 💬 
 147  Viral load driven treatment interruption  [1] 265 💬 

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