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28 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  Baclofen [20] Aert, (r)-baclofen; Arbaclofen; Arbaclofen er tablets; Arbaclofen extended release tablets; Arbaclofen placarbil; Arbaclofen placarbil 15 mg bid; Arbaclofen placarbil 30 mg bid; Arbaclofen placarbil 45 mg bid; Baclofen; Baclofen 20 mg; Baclofen er capsules (grs) 10 mg; Baclofen er capsules (grs) 20 mg; Baclofen er capsules (grs) 30mg; Baclofen er capsules (grs) 40mg; Baclofen er capsules (grs) 50 mg; Baclofen ir; Baclofen tablets usp; Baclofen tablets usp 10 mg; Encapsulated baclofen 20 mg; Rs-baclofen;  [1] D00241 💬 [2] GABBR1, GABBR2 💬 [7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway  [5]  2 , 10, 13, 18, 149 💬
 2  Bupropion [4] Bupropion; Bupropion & citalopram; Bupropion hydrochloride; Wellbutrin (bupropion);  [3] D00817
D07591
D07938 💬		 [2] SLC6A2, SLC6A3 💬 [7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle  [5]  8 , 18, 21, 96, 171 💬
 3  Butylphthalide [2] Butylphthalide; Dl-3-n-butylphthalide (nbp);  -  -  -  [4]  2 ,  6 , 18, 22 💬
 4  Carbonate ion - -  -  -  [12]  2 , 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299 💬
 5  Citalopram [8] 20mg daily citalopram; Bupropion & citalopram; Citalopram; Citalopram 20mg; Escitalopram; Escitalopram oxalate; Escitalopram oxalate antidepressant; Oral escitalopram;  [2] D00822
D07704 💬		 [1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle  [6]  6 ,  8 , 13, 18, 46, 127 💬
 6  Deferiprone [11] Deferiprone; Deferiprone (ferriprox); Deferiprone 20mg; Deferiprone 30mg; Deferiprone 600 mg delayed release tablet; Deferiprone 80 mg/ml oral solution; Deferiprone 80 mg/ml oral solution (ferriprox); Deferiprone dr; Deferiprone oral solution; Deferiprone treated; Ferrprox (deferiprone);  [1] D07416 💬  -  -  [6]  2 ,  6 , 18, 120, 122, 233 💬
 7  Erythropoietin [4] Erythropoietin; Erythropoietin human recombinant (eporh); Recombinant human erythropoietin; Recombinant human erythropoietin(rhepo);  [1] D03231 💬 [1] EPOR 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer  [10]  2 ,  6 , 13, 18, 22, 46, 47, 70, 95, 96 💬
 8  Etravirine [2] Etravirine; Etravirine tablets;  [1] D04112 💬  -  -  [1] 18 💬
 9  Flumazenil [7] 11c-flumazenil; Diagnostic test: pet with [11c]flumazenil; Flumazenil; Pet with 11c-flumazenil; Transdermal flumazenil (added 4/2020); [11c]flumazenil; [18f]flumazenil;  [1] D00697 💬 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction  [5]  6 , 13, 17, 18, 206 💬
 10  Ginkgo biloba [3] Ginkgo biloba; Ginkgo biloba pills sig: 300mg/tid; Standardized ginkgo biloba extract (egb 761 (r);  -  -  -  [4]  6 , 13, 18, 90 💬
 11  Idebenone [2] Idebenone; Idebenone 150 mg film-coated tablets;  [1] D01750 💬  -  -  [5]  6 , 13, 18, 113, 302 💬
 12  Interferon Gamma [5] Fully human anti-interferon gamma monoclonal antibody; Interferon gamma; Interferon gamma 1b; Interferon gamma-1b; Interferon gamma-1b (actimmune);  -  -  -  [8] 18, 65, 85, 107, 228, 299, 301, 326 💬
 13  Interferon gamma-1b [2] Interferon gamma-1b; Interferon gamma-1b (actimmune);  [1] D00747 💬 [2] IFNGR1, IFNGR2 💬 [18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis  [7] 18, 65, 85, 228, 299, 301, 326 💬
 14  Iron [11] 3-hydroxy-2-methyl-4h-pyrane-4-one iron (iii) complex (3:1), ferric (3-hydroxy-2-methyl-4-pyrone), tris-maltol-iron (iii), tri=maltol-iron (iii); Injection of iron; Iron; Iron chelating agents; Iron chelating intervention; Iron sucrose; Iron sulphate; Iron sulphate 200mg coated tablets; Iron supplement 300-600 mg/day; Iron(iii)- hydroxide dextran complex; Oral iron;  -  -  -  [5] 18, 96, 97, 254, 284 💬
 15  Lenograstim [3] Granocyte - 34 million iu (lenograstim rhug-csf); Granocyte lenograstim; Lenograstim;  [1] D03247 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer  [7]  2 , 13, 16, 18, 19, 57, 65 💬
 16  Lithium carbonate [1] Lithium carbonate;  [1] D00801 💬  -  -  [6]  2 , 13, 17, 18, 19, 127 💬
 17  Methylprednisolone [35] Administration of rituximab and methylprednisolone; Corticosteroid treatment (methylprednisolone or prednisolone); Cyclophosphamide, azathioprine,prednisone,methylprednisolone; Infliximab, methylprednisolone, methotrexate; Interferon-beta-1a (avonex) plus methylprednisolone; Intravenous (i.v.) methylprednisolone 1000 mg, total 9; Intravenous methylprednisolone; Iv methylprednisolone; Iv methylprednisolone (steroids); Megadose oral methylprednisolone; Methotrexate + methylprednisolone; Methylprednisolone; Methylprednisolone (drug); Methylprednisolone (mp); Methylprednisolone (mp) or prednisone (pred); Methylprednisolone (or other glucocorticoid); Methylprednisolone (solu-medrol); Methylprednisolone 1250 mg/24h x3 days; Methylprednisolone acetate; Methylprednisolone bolus iv 15 mg/kg/d for 3 days.; Methylprednisolone hemisuccinate; Methylprednisolone iv; Methylprednisolone mylan générique; Methylprednisolone or budesonide; Methylprednisolone or prednisolone; Methylprednisolone po; Methylprednisolone pulse; Methylprednisolone sodium hemisuccinate; Methylprednisolone sodium succinate; Methylprednisolone(intravenously in the 1st-2nd-3rd month ); Methylprednisolone(intravenously in the 1st-3rd-5th month); Oral 5-asa+/-topical 5-asa+iv corticosteroids / po methylprednisolone; Oral methylprednisolone 625 mg/24h x3 days; Prednisone (and methylprednisolone); Prednisone, methylprednisolone,cyclophosphamides;  [6] D00407
D00751
D00979
D05000
D05001
D05002 💬		 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction  [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
 18  Nicotinamide [3] Eh301 (nicotinamide riboside/pterostilbene); Nicotinamide; Nicotinamide riboside;  [1] D00036 💬  -  -  [9]  2 ,  5 ,  6 , 13, 18, 49, 67, 162, 191 💬
 19  Nicotinamide riboside [2] Eh301 (nicotinamide riboside/pterostilbene); Nicotinamide riboside;  -  -  -  [4]  2 ,  6 , 18, 191 💬
 20  Omaveloxolone [10] Omaveloxolone; Omaveloxolone capsules, 10 mg; Omaveloxolone capsules, 150 mg; Omaveloxolone capsules, 160 mg; Omaveloxolone capsules, 2.5 mg; Omaveloxolone capsules, 20 mg; Omaveloxolone capsules, 300 mg; Omaveloxolone capsules, 40 mg; Omaveloxolone capsules, 5 mg; Omaveloxolone capsules, 80 mg;  [1] D10964 💬 [1] NFE2L2 💬 [5] Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum  [1] 18 💬
 21  Resveratrol [2] Liposomed polyphenols resveratrol and curcumin; Resveratrol;  -  -  -  [6]  2 ,  8 , 18, 89, 113, 299 💬
 22  Riluzole [8] Plasma from healthy young people treatment + riluzole; Riluzole; Riluzole (100 mg); Riluzole 50 mg; Riluzole 50 mg (part b); Riluzole oral soluble film; Riluzole oral soluble film (rosf) 50 mg; Riluzole pmcs;  [1] D00775 💬 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 [23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway  [8]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 206 💬
 23  Rosuvastatin [8] Calcium rosuvastatin; Crestor tablets (calcium rosuvastatin) film-coated tablets; Rosuvastatin; Rosuvastatin 10 mg; Rosuvastatin 20mg; Rosuvastatin calcium; Rosuvastatin calcium 40mg; Rosuvastatine eg;  [2] D01915
D08492 💬		 [1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
 24  TAK-831 [1] Tak-831;  -  -  -  [1] 18 💬
 25  Trehalose [1] Trehalose;  -  -  -  [2] 18, 113 💬
 26  Ubidecarenone - [1] D01065 💬  -  -  [13]  2 ,  5 ,  6 ,  8 , 10, 18, 46, 57, 86, 113, 193, 214, 215 💬
 27  Varenicline [2] Varenicline; Varenicline tartrate;  [1] D08669 💬 [2] CHRNA4, CHRNB2 💬 [3] Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction  [2]  6 , 18 💬
 28  Vatiquinone [1] Vatiquinone;  [1] D10407 💬  -  -  [2] 18, 21 💬