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27 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  Acetylcysteine [12] Acetylcysteine; Acetylcysteine effervescent tablets; Acetylcysteine sodium; Fluimucil (acetylcysteine); Glatiramer acetate, n-acetylcysteine; Jaktinib dihydrochloride monohydrate 50mg bid and mimic tablets of jakitinib hydrochloride 75mg bid and acetylcysteine effervescent tablets; Jaktinib dihydrochloride monohydrate 75mg bid and mimic tablets of jakitinib hydrochloride 50mg bid and acetylcysteine effervescent tablets; N acetylcysteine; N-acetylcysteine; N-acetylcysteine (nac); N-acetylcysteine capsule; N-acetylcysteine, (nac);  [1] D00221 💬  -  [17]  6 , 13, 19, 20, 34, 49, 51, 58, 85, 90, 94, 111, 164, 193, 233, 298, 299 💬
 2  Anastrozole [2] Anastrozole; Arimidex (anastrozole);  [1] D00960 💬 [1] CYP19A1 💬 [3] Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis  [3] 78, 86, 193 💬
 3  Beloranib [2] Beloranib; Subcutaneous beloranib in suspension;  -  -  [1] 193 💬
 4  Cannabidiol [11] Avcn583601 (3% cannabidiol cream); Cannabidiol; Cannabidiol (cbd); Cannabidiol , synthetic form; Cannabidiol / dronabinol capsule 5 mg+2,5 mg; Cannabidiol botanical drug substance (cbd bds); Cannabidiol capsule 5 mg; Cannabidiol oral solution; Cannabidiol tablet 10 mg; Cannabidiol vaginal suppository; Delta-9-tetrahydrocannabinol (thc) and cannabidiol (cbd);  [1] D10915 💬 [2] CNR1, CNR2 💬 [4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis  [19]  2 ,  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
 5  Cannabidivarin -  -  [1] 193 💬
 6  Carbetocin [3] Carbetocin; Intranasal carbetocin dose 1; Intranasal carbetocin dose 2;  [1] D07229 💬 [1] OXTR 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway  [1] 193 💬
 7  Chloride ion -  -  [25]  6 , 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 78, 96, 97, 127, 168, 171, 193, 227, 228, 271, 288, 296, 297, 299 💬
 8  Choline [11] Bis-choline tetrathiomolybdate; Choline; Choline chloride; Choline supplementation; Diazoxide choline; Diazoxide choline controlled-release tablet; Rhudex 100 mg (127 mg rhudex choline salt) granules; Rhudex 25 mg (31.75 mg rhudex choline salt) granules; Rhudex 50 mg (63.5 mg rhudex choline salt) granules; Rhudex choline salt; Vitamin: choline bitartrate (2-hydroxyethyl) trimethylammonium salt 1:1;  [1] D07690 💬  -  [4] 93, 171, 193, 299 💬
 9  Corticotropin [8] Adrenocorticotropin hormone; Corticotropin; Corticotropin-releasing hormone; H.p. acthar gel (repository corticotropin injection); Other: corticotropin releasing hormone (crh); Ovine corticotropin-releasing hormone (ocrh); Repository corticotropin injection; Repository corticotropin injection -treatment extension;  [1] D00146 💬 [1] MC2R 💬 [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [13]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
 10  Diazoxide [3] Diazoxide; Diazoxide choline; Diazoxide choline controlled-release tablet;  [1] D00294 💬 [2] ABCC8, KCNJ11 💬 [4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus  [2] 13, 193 💬
 11  Exenatide [5] Exenatide; Exenatide 10 micrograms; Exenatide 5 micrograms; Exenatide extended release 2mg (bydureon); Exenatide pen injector [bydureon];  [1] D04121 💬 [1] GLP1R 💬 [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [4]  6 , 17, 193, 233 💬
 12  Guanfacine [2] Guanfacine; Guanfacine extended release (gxr);  [2] D00606
D08031 💬
[1] ADRA2A 💬 [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [1] 193 💬
 13  Liraglutide [1] Liraglutide;  [1] D06404 💬 [1] GLP1R 💬 [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [3]  6 , 75, 193 💬
 14  Livoletide [1] Livoletide;  -  -  [1] 193 💬
 15  Medical air [5] Medical air; Medical air (sham o2); Medical air vs oxygen; Other: medical air; Sham o2 (medical air);  -  -  [8]  3 , 51, 58, 85, 86, 97, 193, 299 💬
 16  Metoprolol [8] Metoprolol; Metoprolol succinate; Metoprolol succinate + doxazosin; Metoprolol tartrate 50 mg; Metoprolol tartrate oral tablet; Metoprololsuccinat orion 25mg; Metoprololsuccinat ”orion” 25mg; Tesofensine/metoprolol;  [3] D00601
D02358
D05011 💬
[1] ADRB1 💬 [10] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway  [6] 17, 57, 58, 113, 193, 226 💬
 17  Metyrapone [2] Metyrapone; Other: overnight metyrapone test;  [2] D00410
D05019 💬
[1] CYP11B1 💬 [4] Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Steroid hormone biosynthesis  [2] 75, 193 💬
 18  Octreotide [6] Gallium-68-dota-n-octreotide; Octreotide; Octreotide acetate; Octreotide lar; Octreotide lar / sandostatin lar (lar=long acting release); Octreotide-lar;  [2] D00442
D06495 💬
[1] SSTR2 💬 [4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [7] 67, 75, 84, 85, 89, 193, 227 💬
 19  Oxygen [39] Behavioral: respiratory and exercise therapy with supplemental oxygen; Combination product: hyperbaric oxygen therapy-; Continuous oxygen; Device: auto-titrating oxygen system; Device: capacity of muscular oxygen extraction; Device: high flow nasal oxygen cannula; Device: hyperbaric oxygen; Device: intermittent exposure to oxygen via oro-nasal mask; Device: nocturnal oxygen , nocturnal bi-level positive pressure ventilation; Device: oxygen; Device: oxygen saturation; Device: standard oxygen therapy/ra; Diagnostic test: maximum oxygen uptake; Helium / oxygen mixed gas inhalation therapy; Medical air vs oxygen; Medical grade oxygen; Nitric oxide plus oxygen; Other: 60% oxygen; Other: air - oxygen; Other: hyperbaric oxygen; Other: hyperbaric oxygen therapy; Other: muscle oxygenation; Other: optional blood-oxygen-level dependent functionalmri; Other: oxygen; Other: oxygen (2liter/min); Other: oxygen (4liter/min); Other: oxygen - air; Other: oxygen supplementation; Oxygen; Oxygen 40 %; Oxygen supplementation; Oxygen, liquid; Perfluorinated gas/oxygen mixture; Procedure: hyperbaric oxygen; Procedure: hyperbaric oxygen therapy; Procedure: long term oxygen therapy; Procedure: oxygen flow at the optic nerve head measurement; Procedure: supplemental oxygen via a mask; Standard analgesia use [oxygen];  [1] D00003 💬  -  [18]  6 , 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 193, 226, 294, 299, 330 💬
 20  Oxytocin [8] Intranasal oxytocin; Intranasal oxytocin (in-oxt); Oxytocin; Oxytocin (oxt) continuous; Oxytocin 24iu; Oxytocin 48iu; Oxytocin synthetic; Synthetic oxytocin;  [1] D00089 💬 [1] OXTR 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway  [5]  6 , 127, 193, 206, 226 💬
 21  Pitolisant [3] Bf2.649 (pitolisant); Pitolisant; Pitolisant oral tablets;  [1] D10749 💬 [1] HRH3 💬 [1] Neuroactive ligand-receptor interaction  [2]  6 , 193 💬
 22  Rimonabant [1] Rimonabant;  [1] D05731 💬 [1] CNR1 💬 [4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis  [1] 193 💬
 23  Sodium chloride [24] 0.9% sodium chloride; 0.9% sodium chloride (normal saline); 0.9% sodium chloride injection; 0.9% w/v isotonic sodium chloride solution; 0.9% w/v sodium chloride solution; Isotonic sodium chloride solution; Other: 0.9% sodium chloride; Other: 0.9ml sodium chloride; Other: sodium chloride; Physiological serum (sodium chloride); Procedure: 9% sodium chloride (nacl) iv; Sodium chloride; Sodium chloride (7%); Sodium chloride 0,9%; Sodium chloride 0.9%; Sodium chloride 6%; Sodium chloride 7%; Sodium chloride ph. eur.; Sodium chloride solution; Sodium chloride solution 0.9%; Sodium chloride solvent; Sodium pyruvate in 0.9% sodium chloride solution; Solucion de cloruro de sodio sodium chloride solution; Solvente cloruro de sodio sodium chloride solvent;  [1] D02056 💬  -  [20]  6 , 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 78, 96, 168, 193, 227, 228, 271, 288, 299 💬
 24  Somatotropin [3] Recombinant human somatotropin; Somatotropin; Somatotropine;  [1] D02691 💬 [1] GHR 💬 [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway  [20]  2 ,  3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
 25  Tesofensine [3] 1. tesofensine (ns 2330); Tesofensine; Tesofensine/metoprolol;  -  -  [2]  6 , 193 💬
 26  Topiramate [2] Topiramate; Topiramate (drug);  [1] D00537 💬 [36] CA2, CA4, CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬 [52] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [5]  6 , 140, 144, 156, 193 💬
 27  Ubidecarenone [1] D01065 💬  -  [13]  2 ,  5 ,  6 ,  8 , 10, 18, 46, 57, 86, 113, 193, 214, 215 💬