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28 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  Bupropion [4] Bupropion; Bupropion & citalopram; Bupropion hydrochloride; Wellbutrin (bupropion);  [3] D00817
D07591
D07938 💬		 [2] SLC6A2, SLC6A3 💬 [7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle  [5]  8 , 18, 21, 96, 171 💬
 2  Caffeine [6] Caffeine; Caffeine 100 mg; Caffeine 100-200 mg bid; Caffeine alkaloid; Dextromethorphan and caffeine; Other: caffeine;  [2] D00528
D01453 💬		 [11] ADORA1, ADORA2A, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 [22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
 3  Cysteamine [13] Cystagon (cysteamine bitartrate) immediate-release capsules; Cystagon® (cysteamine bitartrate); Cysteamine; Cysteamine (mercaptamine) viscous solution; Cysteamine bitartrate; Cysteamine bitartrate (cystagon); Cysteamine bitartrate (inn: mercaptamine bitartrate; Cysteamine bitartrate (inn: mercaptamine bitartrate ); Cysteamine bitartrate (inn: mercaptamine bitartrate); Cysteamine bitartrate delayed-release capsules; Cysteamine bitartrate delayed-release capsules (rp103); Cysteamine hydrochloride; Other: cysteamine bitartrate;  [2] D03634
D03635 💬		  -  -  [4]  8 , 19, 21, 299 💬
 4  Dexmedetomidine [10] Dexmedetomidine; Dexmedetomidine 1; Dexmedetomidine 2; Dexmedetomidine 3; Dexmedetomidine group; Dexmedetomidine hydrochloride; Dexmedetomidine hydrochloride infusion; Dexmedetomidine with ropivacaine; Fentanyl (low dose) + dexmedetomidine; Scopolamine, atropine, edaravone and dexmedetomidine;  [2] D00514
D01205 💬		 [3] ADRA2A, ADRA2B, ADRA2C 💬 [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [12]  2 ,  4 ,  6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬
 5  Dextromethorphan [10] Dextromethorphan; Dextromethorphan 30 mg; Dextromethorphan and caffeine; Dextromethorphan hbr and quinidine sulfate; Dextromethorphan hydrobromide; Dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg; Dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg; Dextromethorphan/quinidine; Dextromethorphan/quinidine 20mg/10mg (dm/q 20mg/10mg); Dimebon + dextromethorphan;  [3] D00848
D03742
D03744 💬		 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
 6  Elamipretide [4] Elamipretide; Elamipretide (high dose); Elamipretide (intermediate dose); Elamipretide (low dose);  [1] D10925 💬  -  -  [2] 21, 324 💬
 7  Flurbiprofen [3] Bms drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin); Flurbiprofen; Montelukast, flurbiprofen, midazolam, digoxin, pravastatin and bms-986142;  [3] D00330
D01475
D02290 💬		 [2] PTGS1, PTGS2 💬 [23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [3] 13, 21, 46 💬
 8  Haemagglutinin-strain B - -  -  -  [4] 21, 46, 49, 50 💬
 9  Influenza A virus A/Brisbane/59/2007 (H1N1) antigen (formaldehyde inactivated) - -  -  -  [2] 21, 49 💬
 10  Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated) - -  -  -  [2] 21, 49 💬
 11  Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (formaldehyde inactivated) - -  -  -  [2] 21, 49 💬
 12  Influenza A virus A/Texas/50/2012 X-223A (H3N2) antigen (formaldehyde inactivated) - -  -  -  [2] 21, 49 💬
 13  Influenza A virus A/Uruguay/716/2007(H3N2) antigen (formaldehyde inactivated) - -  -  -  [2] 21, 49 💬
 14  Influenza A virus A/Victoria/210/2009 X-187 (H3N2) antigen (formaldehyde inactivated) - -  -  -  [2] 21, 49 💬
 15  Influenza A virus A/Victoria/361/2011 IVR-165 (H3N2) antigen (formaldehyde inactivated) - -  -  -  [2] 21, 49 💬
 16  Influenza B virus B/Brisbane/60/2008 antigen (formaldehyde inactivated) - -  -  -  [2] 21, 49 💬
 17  Influenza B virus B/Massachusetts/2/2012 antigen (formaldehyde inactivated) - -  -  -  [2] 21, 49 💬
 18  Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated) - -  -  -  [2] 21, 49 💬
 19  Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) - -  -  -  [2] 21, 49 💬
 20  Influenza B virus B/Texas/6/2011 antigen (formaldehyde inactivated) - -  -  -  [2] 21, 49 💬
 21  Midazolam [7] Bms drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin); Midazolam; Midazolam 2 mg; Midazolam 3 mg; Midazolam injection; Montelukast, flurbiprofen, midazolam, digoxin, pravastatin and bms-986142; S-ketamine & midazolam;  [3] D00550
D00696
D05028 💬		 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction  [11]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 298 💬
 22  Omeprazole [19] Bms drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin); Clartihromycin, amoxicillin, and omeprazole; Diclofenac + omeprazole; Dimebon + omeprazole; Esomeprazole; Esomeprazole 20 mg; Naproxen 500 mg tablets (pn 200 minus omeprazole); Nexium (esomeprazole magnesium); Omeprazole; Omeprazole (uk licensed generic product); Omeprazole 20 mg; Omeprazole 20mg; Omeprazole 20mg bid; Omeprazole 40 mg; Omeprazole 40mg capsule; Omeprazole magnesium; Omeprazole rectally 1mg/kg; Pn 200 tablets (500 mg naproxen and 20 mg omeprazole); Rifaximin+omeprazole+miralax;  [4] D00455
D01207
D05259
D05261 💬		 [2] ATP4A, ATP4B 💬 [4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation  [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
 23  Propofol [5] Device: propofol dosage; Intubated with propofol (ip); Procedure: sedation with iv propofol; Propofol; Propofol-lipuro;  [1] D00549 💬 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction  [9]  6 , 21, 22, 34, 46, 75, 84, 98, 296 💬
 24  Repaglinide [2] Repaglinide; Repaglinide and insulin;  [1] D00594 💬 [2] ABCC8, KCNJ11 💬 [4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus  [3]  6 , 21, 299 💬
 25  Sevoflurane [3] Intubated with sevoflurane (is); Sevoflurane; Sevoflurane anesthetics;  [1] D00547 💬  -  -  [6]  6 , 21, 22, 34, 98, 296 💬
 26  Sonlicromanol [1] Sonlicromanol;  -  -  -  [1] 21 💬
 27  Uridine triacetate - [1] D09985 💬  -  -  [1] 21 💬
 28  Vatiquinone [1] Vatiquinone;  [1] D10407 💬  -  -  [2] 18, 21 💬